(7 nodes) CNNM, transmembrane domain, and OmpR/PhoB-type DNA-binding domain network (Isoptericola variabilis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AEG45044.1	KEGG: xce:Xcel_2483 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core. (352 aa)
	AEG45045.1	KEGG: xce:Xcel_2484 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; SMART: Cystathionine beta-synthase, core. (454 aa)
	AEG45046.1	Two component transcriptional regulator, winged helix family; Manually curated; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; KEGG: xce:Xcel_2485 winged helix family two component transcriptional regulator; SMART: Signal transduction response regulator, receiver region. (254 aa)
	AEG45573.1	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: xce:Xcel_2793 hypothetical protein. (453 aa)
	AEG45574.1	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; KEGG: xce:Xcel_2794 hypothetical protein. (348 aa)
	AEG45575.1	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: jde:Jden_0148 protein of unknown function DUF21. (427 aa)
	AEG45576.1	Hypothetical protein. (151 aa)

Your Current Organism:

Isoptericola variabilis

NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEG45044.1	AEG45045.1	Isova_2325	Isova_2326	KEGG: xce:Xcel_2483 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.	KEGG: xce:Xcel_2484 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; SMART: Cystathionine beta-synthase, core.	0.898
AEG45044.1	AEG45046.1	Isova_2325	Isova_2327	KEGG: xce:Xcel_2483 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.	Two component transcriptional regulator, winged helix family; Manually curated; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; KEGG: xce:Xcel_2485 winged helix family two component transcriptional regulator; SMART: Signal transduction response regulator, receiver region.	0.533
AEG45044.1	AEG45573.1	Isova_2325	Isova_2888	KEGG: xce:Xcel_2483 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: xce:Xcel_2793 hypothetical protein.	0.570
AEG45044.1	AEG45575.1	Isova_2325	Isova_2890	KEGG: xce:Xcel_2483 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: jde:Jden_0148 protein of unknown function DUF21.	0.571
AEG45045.1	AEG45044.1	Isova_2326	Isova_2325	KEGG: xce:Xcel_2484 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; SMART: Cystathionine beta-synthase, core.	KEGG: xce:Xcel_2483 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.	0.898
AEG45045.1	AEG45046.1	Isova_2326	Isova_2327	KEGG: xce:Xcel_2484 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; SMART: Cystathionine beta-synthase, core.	Two component transcriptional regulator, winged helix family; Manually curated; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; KEGG: xce:Xcel_2485 winged helix family two component transcriptional regulator; SMART: Signal transduction response regulator, receiver region.	0.533
AEG45045.1	AEG45574.1	Isova_2326	Isova_2889	KEGG: xce:Xcel_2484 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; SMART: Cystathionine beta-synthase, core.	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; KEGG: xce:Xcel_2794 hypothetical protein.	0.571
AEG45046.1	AEG45044.1	Isova_2327	Isova_2325	Two component transcriptional regulator, winged helix family; Manually curated; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; KEGG: xce:Xcel_2485 winged helix family two component transcriptional regulator; SMART: Signal transduction response regulator, receiver region.	KEGG: xce:Xcel_2483 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.	0.533
AEG45046.1	AEG45045.1	Isova_2327	Isova_2326	Two component transcriptional regulator, winged helix family; Manually curated; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; KEGG: xce:Xcel_2485 winged helix family two component transcriptional regulator; SMART: Signal transduction response regulator, receiver region.	KEGG: xce:Xcel_2484 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; SMART: Cystathionine beta-synthase, core.	0.533
AEG45573.1	AEG45044.1	Isova_2888	Isova_2325	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: xce:Xcel_2793 hypothetical protein.	KEGG: xce:Xcel_2483 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.	0.570
AEG45573.1	AEG45574.1	Isova_2888	Isova_2889	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: xce:Xcel_2793 hypothetical protein.	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; KEGG: xce:Xcel_2794 hypothetical protein.	0.903
AEG45573.1	AEG45575.1	Isova_2888	Isova_2890	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: xce:Xcel_2793 hypothetical protein.	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: jde:Jden_0148 protein of unknown function DUF21.	0.825
AEG45573.1	AEG45576.1	Isova_2888	Isova_2891	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: xce:Xcel_2793 hypothetical protein.	Hypothetical protein.	0.584
AEG45574.1	AEG45045.1	Isova_2889	Isova_2326	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; KEGG: xce:Xcel_2794 hypothetical protein.	KEGG: xce:Xcel_2484 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; SMART: Cystathionine beta-synthase, core.	0.571
AEG45574.1	AEG45573.1	Isova_2889	Isova_2888	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; KEGG: xce:Xcel_2794 hypothetical protein.	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: xce:Xcel_2793 hypothetical protein.	0.903
AEG45574.1	AEG45575.1	Isova_2889	Isova_2890	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; KEGG: xce:Xcel_2794 hypothetical protein.	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: jde:Jden_0148 protein of unknown function DUF21.	0.899
AEG45574.1	AEG45576.1	Isova_2889	Isova_2891	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; KEGG: xce:Xcel_2794 hypothetical protein.	Hypothetical protein.	0.584
AEG45575.1	AEG45044.1	Isova_2890	Isova_2325	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: jde:Jden_0148 protein of unknown function DUF21.	KEGG: xce:Xcel_2483 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.	0.571
AEG45575.1	AEG45573.1	Isova_2890	Isova_2888	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: jde:Jden_0148 protein of unknown function DUF21.	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: xce:Xcel_2793 hypothetical protein.	0.825
AEG45575.1	AEG45574.1	Isova_2890	Isova_2889	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; KEGG: jde:Jden_0148 protein of unknown function DUF21.	PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; KEGG: xce:Xcel_2794 hypothetical protein.	0.899