STRINGSTRING
ADV25916.1 ADV25916.1 ADV25917.1 ADV25917.1 dut dut pyrE pyrE ADV26129.1 ADV26129.1 ADV26282.1 ADV26282.1 thyA thyA ADV26582.1 ADV26582.1 surE surE ADV26698.1 ADV26698.1 pyrG pyrG pyrH pyrH upp upp ADV27065.1 ADV27065.1 pyrD pyrD cmk cmk ndk ndk ADV27306.1 ADV27306.1 carB carB carA carA dcd dcd tmk tmk pyrB pyrB ADV28445.1 ADV28445.1 tdk tdk pyrF pyrF
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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ADV25916.1Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (814 aa)
ADV25917.1Ribonucleotide reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (354 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (154 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (219 aa)
ADV26129.1Cytosine deaminase; KEGG: xcb:XC_0670 catalytic motif; other site; PFAM: CMP/dCMP deaminase zinc-binding. (158 aa)
ADV26282.1PFAM: nitroreductase; KEGG: sml:Smlt0482 hypothetical protein. (195 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
ADV26582.1MazG family protein; KEGG: sml:Smlt3663 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. (274 aa)
surEStationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (264 aa)
ADV26698.1PFAM: Conserved hypothetical protein CHP00730; KEGG: sml:Smlt1620 putative lysine decarboxylase protein. (460 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (554 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (210 aa)
ADV27065.1PFAM: amidohydrolase; KEGG: smt:Smal_2736 dihydroorotase. (450 aa)
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (352 aa)
cmkTIGRFAM: cytidylate kinase; KEGG: smt:Smal_1645 cytidylate kinase; PFAM: cytidylate kinase region. (225 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
ADV27306.15'-nucleotidase; KEGG: sml:Smlt3165 putative 5-nucleotidase; PFAM: 5-nucleotidase. (310 aa)
carBKEGG: xal:XALc_1339 probable carbamoyl-phosphate synthetase large chain protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family. (1080 aa)
carAKEGG: xcv:XCV1907 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. (398 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (190 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (223 aa)
pyrBKEGG: xca:xccb100_1415 aspartate carbamoyltransferase catalytic subunit; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (314 aa)
ADV28445.1Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (718 aa)
tdkKEGG: smt:Smal_0047 thymidine kinase; PFAM: thymidine kinase. (206 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (240 aa)
Your Current Organism:
Pseudoxanthomonas suwonensis 111
NCBI taxonomy Id: 743721
Other names: P. suwonensis 11-1, Pseudoxanthomonas suwonensis 11-1, Pseudoxanthomonas suwonensis str. 11-1, Pseudoxanthomonas suwonensis strain 11-1
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