STRINGSTRING
ADZ76639.1 ADZ76639.1 ADZ76948.1 ADZ76948.1 lipB lipB glyA glyA ADZ77709.1 ADZ77709.1 pdhA pdhA ADZ77719.1 ADZ77719.1 gcvT gcvT ADZ77872.1 ADZ77872.1 ADZ77899.1 ADZ77899.1 ADZ77966.1 ADZ77966.1 ADZ77967.1 ADZ77967.1 ADZ77968.1 ADZ77968.1 fumC fumC purU purU ADZ78246.1 ADZ78246.1 ADZ78247.1 ADZ78247.1 ADZ78252.1 ADZ78252.1 ADZ78272.1 ADZ78272.1 gcvP gcvP ADZ78645.1 ADZ78645.1 gcvH gcvH ADZ78760.1 ADZ78760.1 ADZ78791.1 ADZ78791.1 mqo mqo sucD sucD ADZ79090.1 ADZ79090.1 ADZ79120.1 ADZ79120.1 pckA pckA ADZ79689.1 ADZ79689.1 ADZ79708.1 ADZ79708.1 ADZ79761.1 ADZ79761.1 sucC sucC ADZ79977.1 ADZ79977.1 ADZ80163.1 ADZ80163.1 mdh mdh prpB prpB ADZ80677.1 ADZ80677.1 ADZ80678.1 ADZ80678.1 ADZ81381.1 ADZ81381.1 ADZ81668.1 ADZ81668.1 lipA lipA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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ADZ76639.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (907 aa)
ADZ76948.1TIGRFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type; KEGG: zpr:ZPR_3604 NADP-dependent monomeric type isocitrate dehydrogenase; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family. (744 aa)
lipBOctanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (238 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa)
ADZ77709.1Acylphosphatase; KEGG: phe:Phep_3843 acylphosphatase; HAMAP: Acylphosphatase; PFAM: Acylphosphatase-like. (90 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (331 aa)
ADZ77719.1Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (548 aa)
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (359 aa)
ADZ77872.1Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
ADZ77899.1KEGG: cpi:Cpin_3681 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family. (502 aa)
ADZ77966.1KEGG: phe:Phep_0212 succinate dehydrogenase/fumarate reductase iron-sulfur subunit. (259 aa)
ADZ77967.1TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; KEGG: chu:CHU_2473 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal. (645 aa)
ADZ77968.1TIGRFAM: Succinate dehydrogenase, cytochrome b558 subunit; KEGG: lby:Lbys_2049 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (257 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (279 aa)
ADZ78246.12-oxoglutarate dehydrogenase, E1 subunit; SMART: Transketolase-like, pyrimidine-binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component; KEGG: phe:Phep_3716 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component. (937 aa)
ADZ78247.12-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (519 aa)
ADZ78252.1TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: phe:Phep_3710 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. (467 aa)
ADZ78272.1TIGRFAM: Succinate CoA transferase; KEGG: lby:Lbys_1257 succinate CoA transferase; PFAM: Acetyl-CoA hydrolase/transferase. (498 aa)
gcvPGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (960 aa)
ADZ78645.1Malic protein NAD-binding protein; KEGG: phe:Phep_3833 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), phosphate acetyltransferase; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SMART: Malic enzyme, NAD-binding. (765 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
ADZ78760.1KEGG: pdi:BDI_0987 pyruvate dehydrogenase; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Belongs to the TPP enzyme family. (578 aa)
ADZ78791.1KEGG: dfe:Dfer_1208 aconitate hydratase; TIGRFAM: Aconitase, mitochondrial-like; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel. (757 aa)
mqoPFAM: Malate:quinone-oxidoreductase; TIGRFAM: Malate:quinone-oxidoreductase; KEGG: cpi:Cpin_2378 malate:quinone oxidoreductase; HAMAP: Malate:quinone-oxidoreductase. (504 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
ADZ79090.1Dihydrolipoyllysine-residue acetyltransferase; KEGG: phe:Phep_1872 catalytic domain of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding. (447 aa)
ADZ79120.1Dihydrolipoyl dehydrogenase; KEGG: dfe:Dfer_1248 mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. (463 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (536 aa)
ADZ79689.1TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic; KEGG: cpi:Cpin_6591 isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase. (422 aa)
ADZ79708.1Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (861 aa)
ADZ79761.1KEGG: phe:Phep_1509 transketolase domain protein; PFAM: Transketolase, C-terminal; Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component; SMART: Transketolase-like, pyrimidine-binding domain. (805 aa)
sucCSuccinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)
ADZ79977.1TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: phe:Phep_3001 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. (462 aa)
ADZ80163.1TIGRFAM: Citrate synthase, type II; KEGG: phe:Phep_2053 citrate synthase I; PFAM: Citrate synthase-like; Belongs to the citrate synthase family. (428 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (293 aa)
ADZ80677.1TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; KEGG: bvi:Bcep1808_3679 methylcitrate synthase; PFAM: Citrate synthase-like; Belongs to the citrate synthase family. (383 aa)
ADZ80678.1TIGRFAM: 2-methylcitrate dehydratase PrpD; KEGG: bgf:BC1003_4612 2-methylcitrate dehydratase; PFAM: MmgE/PrpD. (481 aa)
ADZ81381.1TIGRFAM: Succinate dehydrogenase, cytochrome b558 subunit; KEGG: dfe:Dfer_3969 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (255 aa)
ADZ81668.1acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (639 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (293 aa)
Your Current Organism:
Sphingobacterium sp. 21
NCBI taxonomy Id: 743722
Other names: S. sp. 21
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