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carA | TIGRFAM: Carbamoyl-phosphate synthase, small subunit; KEGG: phe:Phep_0705 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; Belongs to the CarA family. (366 aa) | ||||
ADZ76931.1 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (272 aa) | ||||
ADZ77299.1 | PFAM: Phosphoribosyltransferase; KEGG: phe:Phep_4038 uracil phosphoribosyltransferase. (214 aa) | ||||
ADZ77413.1 | PFAM: Inosine/uridine-preferring nucleoside hydrolase domain; KEGG: dfe:Dfer_4323 inosine/uridine-preferring nucleoside hydrolase. (331 aa) | ||||
pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (235 aa) | ||||
ADZ77691.1 | TIGRFAM: Carbamoyl-phosphate synthase, large subunit; KEGG: phe:Phep_0124 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation. (938 aa) | ||||
ADZ77716.1 | PFAM: Phosphoribosyltransferase; KEGG: phe:Phep_3621 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase. (171 aa) | ||||
ADZ77816.1 | TIGRFAM: Deoxyguanosinetriphosphate triphosphohydrolase; KEGG: phe:Phep_2365 deoxyguanosinetriphosphate triphosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain. (448 aa) | ||||
ADZ77930.1 | TIGRFAM: Hypoxanthine phosphoribosyl transferase; KEGG: phe:Phep_0044 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (177 aa) | ||||
ADZ78028.1 | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (191 aa) | ||||
purD | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: phe:Phep_0267 phosphoribosylamine--glycine ligase; Belongs to the GARS family. (426 aa) | ||||
gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (188 aa) | ||||
ADZ78769.1 | KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II. (636 aa) | ||||
ADZ78771.1 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: phe:Phep_0992 CMP/dCMP deaminase zinc-binding. (149 aa) | ||||
pyrB | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; HAMAP: Aspartate carbamoyltransferase, eukaryotic; KEGG: phe:Phep_1173 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (312 aa) | ||||
ADZ78786.1 | KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase. (183 aa) | ||||
guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (516 aa) | ||||
apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (175 aa) | ||||
tdk | HAMAP: Thymidine kinase, subgroup; KEGG: phe:Phep_0802 thymidine kinase; PFAM: Thymidine kinase. (193 aa) | ||||
purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain; Methylglyoxal synthase-like domain; TIGRFAM: AICARFT/IMPCHase bienzyme; KEGG: phe:Phep_0809 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; Methylglyoxal synthase-like domain. (508 aa) | ||||
purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (197 aa) | ||||
purC | HAMAP: SAICAR synthetase; KEGG: phe:Phep_1864 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (318 aa) | ||||
ADZ79473.1 | KEGG: phe:Phep_3079 AMP nucleosidase; TIGRFAM: AMP nucleosidase, putative; PFAM: Nucleoside phosphorylase domain. (272 aa) | ||||
purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (425 aa) | ||||
pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (216 aa) | ||||
purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa) | ||||
purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa) | ||||
ADZ79780.1 | Guanine deaminase; KEGG: sli:Slin_2805 CMP/dCMP deaminase zinc-binding protein; PFAM: CMP/dCMP deaminase, zinc-binding. (160 aa) | ||||
surE | Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (250 aa) | ||||
ADZ79948.1 | KEGG: phe:Phep_3862 5 nucleotidase deoxy cytosolic type C. (188 aa) | ||||
folD | Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa) | ||||
pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (345 aa) | ||||
ADZ80084.1 | MazG family protein; KEGG: phe:Phep_1231 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. (267 aa) | ||||
ADZ80158.1 | TIGRFAM: Adenylosuccinate lyase; KEGG: phe:Phep_2933 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (445 aa) | ||||
guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (491 aa) | ||||
purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1219 aa) | ||||
ADZ80420.1 | Allantoinase; KEGG: phe:Phep_3229 dihydroorotase; PFAM: Amidohydrolase 1. (445 aa) | ||||
ADZ80518.1 | KEGG: cpi:Cpin_6522 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase-related protein, C-terminal. (391 aa) | ||||
pyrF | KEGG: lby:Lbys_3332 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase domain; TIGRFAM: Orotidine 5'-phosphate decarboxylase, type 2; HAMAP: Orotidine 5'-phosphate decarboxylase, type 2; SMART: Orotidine 5'-phosphate decarboxylase domain; Belongs to the OMP decarboxylase family. Type 2 subfamily. (278 aa) | ||||
ADZ81175.1 | KEGG: phe:Phep_2916 uridine kinase; PFAM: Phosphoribulokinase/uridine kinase. (210 aa) | ||||
purA-2 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa) | ||||
ADZ81625.1 | KEGG: phe:Phep_3185 dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase; PFAM: Amidohydrolase 1. (423 aa) | ||||
surE-2 | Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (256 aa) |