STRINGSTRING
miaB miaB ADZ77642.1 ADZ77642.1 ADZ77686.1 ADZ77686.1 ADZ77687.1 ADZ77687.1 dxs dxs rlmN rlmN ADZ77927.1 ADZ77927.1 ADZ77928.1 ADZ77928.1 ispF ispF ispG ispG dxr dxr ispE ispE ADZ79598.1 ADZ79598.1 ADZ79599.1 ADZ79599.1 ADZ79635.1 ADZ79635.1 ADZ80175.1 ADZ80175.1 ADZ80176.1 ADZ80176.1 ispD ispD ADZ81673.1 ADZ81673.1 rimO rimO ADZ81677.1 ADZ81677.1 ADZ81691.1 ADZ81691.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
miaB(Dimethylallyl)adenosine tRNA methylthiotransferase miaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (477 aa)
ADZ77642.1Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (282 aa)
ADZ77686.1KEGG: phe:Phep_0545 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (323 aa)
ADZ77687.1KEGG: fba:FIC_01446 membrane protein, TerC family; TIGRFAM: Integral membrane protein TerC, riboswitch-linked; PFAM: Integral membrane protein TerC. (349 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (642 aa)
rlmNRibosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (379 aa)
ADZ77927.1PFAM: NIF system FeS cluster assembly, NifU, C-terminal; KEGG: phe:Phep_0047 nitrogen-fixing NifU domain protein. (92 aa)
ADZ77928.1ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (362 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (670 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (392 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (274 aa)
ADZ79598.1TIGRFAM: MiaB-like tRNA modifying enzyme; Methylthiotransferase; PFAM: Methylthiotransferase, N-terminal; Radical SAM; KEGG: phe:Phep_2937 MiaB-like tRNA modifying enzyme; SMART: Elongator protein 3/MiaB/NifB. (439 aa)
ADZ79599.1PFAM: NLP/P60; KEGG: phe:Phep_1884 NLP/P60 protein. (200 aa)
ADZ79635.1Geranyltranstransferase; KEGG: phe:Phep_1628 polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (324 aa)
ADZ80175.1PFAM: NUDIX hydrolase domain; TIGRFAM: Isopentenyl-diphosphate delta-isomerase, type 1; HAMAP: Isopentenyl-diphosphate delta-isomerase, type 1; KEGG: cpi:Cpin_4731 isopentenyl-diphosphate delta-isomerase, type 1. (172 aa)
ADZ80176.1Methyltransferase small; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). (241 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (233 aa)
ADZ81673.1KEGG: phe:Phep_3523 hypothetical protein. (60 aa)
rimORibosomal protein S12 methylthiotransferase rimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (442 aa)
ADZ81677.1KEGG: phe:Phep_1307 protein of unknown function DUF419. (117 aa)
ADZ81691.1Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (246 aa)
Your Current Organism:
Sphingobacterium sp. 21
NCBI taxonomy Id: 743722
Other names: S. sp. 21
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.