STRINGSTRING
AEJ20046.1 AEJ20046.1 AEJ18226.1 AEJ18226.1 AEJ18349.1 AEJ18349.1 pfkA pfkA glpK glpK AEJ18450.1 AEJ18450.1 AEJ18471.1 AEJ18471.1 AEJ18515.1 AEJ18515.1 AEJ18618.1 AEJ18618.1 eno eno AEJ18760.1 AEJ18760.1 kduI kduI pfp pfp AEJ18930.1 AEJ18930.1 rbsD rbsD AEJ18977.1 AEJ18977.1 AEJ19016.1 AEJ19016.1 deoC deoC AEJ19131.1 AEJ19131.1 AEJ19142.1 AEJ19142.1 AEJ19159.1 AEJ19159.1 pgi pgi AEJ19513.1 AEJ19513.1 AEJ19838.1 AEJ19838.1 tpiA tpiA pgk pgk AEJ20923.1 AEJ20923.1 araA araA AEJ20739.1 AEJ20739.1 AEJ20673.1 AEJ20673.1 AEJ20552.1 AEJ20552.1 fucI fucI AEJ20198.1 AEJ20198.1 pfkA-2 pfkA-2 AEJ19965.1 AEJ19965.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEJ20046.1Glycoside hydrolase family 2 TIM barrel. (1210 aa)
AEJ18226.1Pectate lyase/Amb allergen. (475 aa)
AEJ18349.1SlyX family protein. (67 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (455 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (498 aa)
AEJ18450.1Hypothetical protein. (346 aa)
AEJ18471.1Hypothetical protein. (158 aa)
AEJ18515.1Beta-mannosidase. (902 aa)
AEJ18618.1Galactose-1-phosphate uridylyltransferase. (352 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
AEJ18760.1Alpha-glucuronidase; Belongs to the glycosyl hydrolase 67 family. (684 aa)
kduI4-deoxy-L-threo-5-hexosulose-uronateketol- isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (278 aa)
pfpDiphosphate/fructose-6-phosphate1-phosphotransfe rase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (551 aa)
AEJ18930.1Pyruvate kinase; Belongs to the pyruvate kinase family. (599 aa)
rbsDD-ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (131 aa)
AEJ18977.1Endo-1,4-beta-xylanase. (361 aa)
AEJ19016.1Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (555 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (223 aa)
AEJ19131.1Hypothetical protein. (348 aa)
AEJ19142.1Hexokinase. (452 aa)
AEJ19159.1Cephalosporin-C deacetylase. (340 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (527 aa)
AEJ19513.1Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (217 aa)
AEJ19838.1Fructose-1,6-bisphosphate aldolase, class II. (332 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (419 aa)
AEJ20923.1Hypothetical protein. (349 aa)
araAL-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (499 aa)
AEJ20739.1Zn-dependent hydrolase. (314 aa)
AEJ20673.1Glycoside hydrolase family 5; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (629 aa)
AEJ20552.1Cellulase; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (342 aa)
fucIL-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose. (606 aa)
AEJ20198.1L-fucose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (438 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (368 aa)
AEJ19965.1Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (356 aa)
Your Current Organism:
Treponema caldarium
NCBI taxonomy Id: 744872
Other names: Spirochaeta caldaria DSM 7334, Spirochaeta caldaria H1, T. caldarium DSM 7334, Treponema caldaria DSM 7334, Treponema caldaria H1, Treponema caldaria str. DSM 7334, Treponema caldaria strain DSM 7334, Treponema caldarium DSM 7334
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