STRINGSTRING
AEJ18237.1 AEJ18237.1 AEJ18289.1 AEJ18289.1 AEJ18310.1 AEJ18310.1 trpF trpF AEJ18351.1 AEJ18351.1 AEJ18365.1 AEJ18365.1 groL groL truA truA AEJ18673.1 AEJ18673.1 AEJ18688.1 AEJ18688.1 AEJ18691.1 AEJ18691.1 kduI kduI uxaC uxaC AEJ18905.1 AEJ18905.1 AEJ18908.1 AEJ18908.1 AEJ18962.1 AEJ18962.1 rbsD rbsD AEJ18987.1 AEJ18987.1 AEJ19016.1 AEJ19016.1 AEJ19073.1 AEJ19073.1 AEJ19132.1 AEJ19132.1 AEJ19164.1 AEJ19164.1 AEJ19178.1 AEJ19178.1 AEJ19188.1 AEJ19188.1 AEJ19197.1 AEJ19197.1 tig tig murI murI pgi pgi truA-2 truA-2 AEJ19420.1 AEJ19420.1 AEJ19472.1 AEJ19472.1 queA queA truB truB AEJ19513.1 AEJ19513.1 AEJ19523.1 AEJ19523.1 AEJ19545.1 AEJ19545.1 nnrD nnrD AEJ19651.1 AEJ19651.1 AEJ19716.1 AEJ19716.1 AEJ19725.1 AEJ19725.1 AEJ19726.1 AEJ19726.1 AEJ19766.1 AEJ19766.1 AEJ19767.1 AEJ19767.1 glmS glmS AEJ19800.1 AEJ19800.1 glmE glmE topA topA AEJ19845.1 AEJ19845.1 AEJ19848.1 AEJ19848.1 tpiA tpiA AEJ20198.1 AEJ20198.1 AEJ20214.1 AEJ20214.1 fucI fucI AEJ20360.1 AEJ20360.1 AEJ20411.1 AEJ20411.1 rpiA rpiA AEJ20545.1 AEJ20545.1 nagB nagB AEJ20604.1 AEJ20604.1 AEJ20765.1 AEJ20765.1 AEJ20840.1 AEJ20840.1 xylA xylA araA araA gyrA gyrA gyrB gyrB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEJ18237.1Hypothetical protein. (416 aa)
AEJ18289.1Protein of unknown function DUF1498. (252 aa)
AEJ18310.1Peptidylprolyl isomerase. (203 aa)
trpFIndole-3-glycerol-phosphate synthase., Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (645 aa)
AEJ18351.1Hypothetical protein. (457 aa)
AEJ18365.1Peptidylprolyl isomerase. (345 aa)
groL60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (546 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (266 aa)
AEJ18673.1UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing. (389 aa)
AEJ18688.1UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (375 aa)
AEJ18691.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa)
kduI4-deoxy-L-threo-5-hexosulose-uronateketol- isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (278 aa)
uxaCUronate isomerase. (478 aa)
AEJ18905.1UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (325 aa)
AEJ18908.1Lysine 2,3-aminomutase YodO family protein. (376 aa)
AEJ18962.1PpiC-type peptidyl-prolyl cis-trans isomerase. (512 aa)
rbsDD-ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (131 aa)
AEJ18987.1Peptidylprolyl isomerase. (231 aa)
AEJ19016.1Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (555 aa)
AEJ19073.1PpiC-type peptidyl-prolyl cis-trans isomerase. (348 aa)
AEJ19132.1Hypothetical protein. (313 aa)
AEJ19164.1Pseudouridine synthase. (284 aa)
AEJ19178.1Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I. (589 aa)
AEJ19188.1Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I. (647 aa)
AEJ19197.1Pseudouridine synthase. (224 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (469 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (286 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (527 aa)
truA-2tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (250 aa)
AEJ19420.1Pseudouridine synthase; Belongs to the pseudouridine synthase RluA family. (343 aa)
AEJ19472.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (339 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (306 aa)
AEJ19513.1Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (217 aa)
AEJ19523.1Pseudouridine synthase Rsu; Belongs to the pseudouridine synthase RsuA family. (250 aa)
AEJ19545.1Chorismate mutase. (129 aa)
nnrDYjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. (556 aa)
AEJ19651.1Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (343 aa)
AEJ19716.1Hypothetical protein. (310 aa)
AEJ19725.1Pseudouridine synthase. (253 aa)
AEJ19726.1Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (315 aa)
AEJ19766.1DNA topoisomerase (ATP-hydrolyzing). (640 aa)
AEJ19767.1DNA topoisomerase type IIA subunit B region 2 domain protein. (603 aa)
glmSMethylaspartate mutase S chain; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate). (151 aa)
AEJ19800.1Conserved hypothetical protein CHP01319, GlmL. (468 aa)
glmEMethylaspartate mutase, E subunit; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate). (482 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (712 aa)
AEJ19845.1Mannose-6-phosphate isomerase, class I. (410 aa)
AEJ19848.1PpiC-type peptidyl-prolyl cis-trans isomerase. (92 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
AEJ20198.1L-fucose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (438 aa)
AEJ20214.1Sugar-phosphate isomerase, RpiB/LacA/LacB family. (162 aa)
fucIL-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose. (606 aa)
AEJ20360.1RbsD or FucU transport; Belongs to the RbsD / FucU family. (145 aa)
AEJ20411.1Lycopene cyclase domain protein. (229 aa)
rpiARibose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (233 aa)
AEJ20545.1phosphoribosyl-ATP diphosphatase. (423 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (266 aa)
AEJ20604.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (372 aa)
AEJ20765.1Pseudouridine synthase. (235 aa)
AEJ20840.1Pseudouridine synthase Rsu; Belongs to the pseudouridine synthase RsuA family. (242 aa)
xylAXylose isomerase; Belongs to the xylose isomerase family. (447 aa)
araAL-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (499 aa)
gyrADNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (837 aa)
gyrBDNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (635 aa)
Your Current Organism:
Treponema caldarium
NCBI taxonomy Id: 744872
Other names: Spirochaeta caldaria DSM 7334, Spirochaeta caldaria H1, T. caldarium DSM 7334, Treponema caldaria DSM 7334, Treponema caldaria H1, Treponema caldaria str. DSM 7334, Treponema caldaria strain DSM 7334, Treponema caldarium DSM 7334
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