(25 nodes) Mixed, incl. Metallo-beta-lactamase superfamily, and Rhodanese Homology Domain network (Ahrensia sp. R2A130)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EFL90027.1	Metallo-beta-lactamase superfamily protein; Identified by match to protein family HMM PF00753; match to protein family HMM TIGR01409. (314 aa)
	EFL90300.1	Camp protein. (57 aa)
	EFL90301.1	Rhodanese domain-containing protein. (265 aa)
	EFL90302.1	Chromate transporter; Identified by match to protein family HMM PF02417; match to protein family HMM TIGR00937. (422 aa)
	mraW	S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (394 aa)
	EFL88620.1	Identified by match to protein family HMM PF01965. (224 aa)
	EFL89132.1	Lactoylglutathione lyase; Identified by match to protein family HMM PF00903. (146 aa)
	gloB	Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (258 aa)
	truA	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (251 aa)
	EFL89793.1	Ornithine-acyl[acyl carrier protein] N-acyltransferase. (300 aa)
	EFL89905.1	Rhodanese domain-containing protein. (146 aa)
	EFL91025.1	Beta-lactamase domain-containing protein; Identified by match to protein family HMM PF00753. (213 aa)
	EFL87586.1	Glyoxylase B2; Identified by match to protein family HMM PF00753. (302 aa)
	EFL87617.1	Rhodanese domain protein. (130 aa)
	EFL87619.1	Sulfatase; Identified by match to protein family HMM PF00884. (582 aa)
	EFL87620.1	Hypothetical protein; Identified by glimmer; putative. (37 aa)
	EFL87707.1	Beta-lactamase domain-containing protein; Identified by match to protein family HMM PF00753. (260 aa)
	EFL88369.1	Hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF03471. (399 aa)
	ybeY	Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (172 aa)
	phoH	Phosphate starvation inducible protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02562. (365 aa)
	miaB	tRNA-I(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (477 aa)
	EFL88373.1	1-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by match to protein family HMM PF01553. (263 aa)
	fur-2	Ferric uptake regulation protein; Identified by match to protein family HMM PF01475; Belongs to the Fur family. (139 aa)
	glnD	protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (967 aa)
	mviN	Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (542 aa)

Your Current Organism:

Ahrensia sp. R2A130

NCBI taxonomy Id: 744979
Other names: A. sp. R2A130

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFL87586.1	EFL87617.1	R2A130_2737	R2A130_2767	Glyoxylase B2; Identified by match to protein family HMM PF00753.	Rhodanese domain protein.	0.431
EFL87586.1	EFL89132.1	R2A130_2737	R2A130_1622	Glyoxylase B2; Identified by match to protein family HMM PF00753.	Lactoylglutathione lyase; Identified by match to protein family HMM PF00903.	0.523
EFL87586.1	EFL90301.1	R2A130_2737	R2A130_0372	Glyoxylase B2; Identified by match to protein family HMM PF00753.	Rhodanese domain-containing protein.	0.590
EFL87586.1	truA	R2A130_2737	R2A130_2378	Glyoxylase B2; Identified by match to protein family HMM PF00753.	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.404
EFL87586.1	ybeY	R2A130_2737	R2A130_2890	Glyoxylase B2; Identified by match to protein family HMM PF00753.	Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.405
EFL87617.1	EFL87586.1	R2A130_2767	R2A130_2737	Rhodanese domain protein.	Glyoxylase B2; Identified by match to protein family HMM PF00753.	0.431
EFL87617.1	EFL87619.1	R2A130_2767	R2A130_2769	Rhodanese domain protein.	Sulfatase; Identified by match to protein family HMM PF00884.	0.548
EFL87617.1	EFL87620.1	R2A130_2767	R2A130_2770	Rhodanese domain protein.	Hypothetical protein; Identified by glimmer; putative.	0.548
EFL87617.1	gloB	R2A130_2767	R2A130_1817	Rhodanese domain protein.	Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.	0.428
EFL87617.1	mraW	R2A130_2767	R2A130_0938	Rhodanese domain protein.	S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.	0.515
EFL87617.1	truA	R2A130_2767	R2A130_2378	Rhodanese domain protein.	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.523
EFL87617.1	ybeY	R2A130_2767	R2A130_2890	Rhodanese domain protein.	Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.924
EFL87619.1	EFL87617.1	R2A130_2769	R2A130_2767	Sulfatase; Identified by match to protein family HMM PF00884.	Rhodanese domain protein.	0.548
EFL87619.1	EFL87620.1	R2A130_2769	R2A130_2770	Sulfatase; Identified by match to protein family HMM PF00884.	Hypothetical protein; Identified by glimmer; putative.	0.773
EFL87620.1	EFL87617.1	R2A130_2770	R2A130_2767	Hypothetical protein; Identified by glimmer; putative.	Rhodanese domain protein.	0.548
EFL87620.1	EFL87619.1	R2A130_2770	R2A130_2769	Hypothetical protein; Identified by glimmer; putative.	Sulfatase; Identified by match to protein family HMM PF00884.	0.773
EFL87707.1	EFL89905.1	R2A130_2857	R2A130_2517	Beta-lactamase domain-containing protein; Identified by match to protein family HMM PF00753.	Rhodanese domain-containing protein.	0.472
EFL87707.1	EFL90301.1	R2A130_2857	R2A130_0372	Beta-lactamase domain-containing protein; Identified by match to protein family HMM PF00753.	Rhodanese domain-containing protein.	0.590
EFL87707.1	ybeY	R2A130_2857	R2A130_2890	Beta-lactamase domain-containing protein; Identified by match to protein family HMM PF00753.	Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.405
EFL88369.1	EFL88373.1	R2A130_2889	R2A130_2893	Hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF03471.	1-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by match to protein family HMM PF01553.	0.545