STRINGSTRING
dapA dapA EFL88790.1 EFL88790.1 EFL88791.1 EFL88791.1 aroC aroC frc_1 frc_1 EFL87948.1 EFL87948.1 aroB aroB aroK_2 aroK_2 lysA lysA EFL88113.1 EFL88113.1 aroA aroA EFL89523.1 EFL89523.1 aroQ aroQ EFL89564.1 EFL89564.1 dapF dapF asd asd aroE aroE dapE dapE dapD dapD EFL87599.1 EFL87599.1 dapB dapB folC folC EFL87736.1 EFL87736.1 putA putA frc_2 frc_2 EFL87540.1 EFL87540.1 folB folB folK folK EFL90197.1 EFL90197.1 EFL90100.1 EFL90100.1 folP folP EFL90490.1 EFL90490.1 nadA nadA kynU kynU
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa)
EFL88790.1Glutamate synthase small chain; Identified by match to protein family HMM PF07992; match to protein family HMM TIGR01317. (477 aa)
EFL88791.1Ferredoxin-dependent glutamate synthase 1; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. (1570 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa)
frc_1formyl-CoA transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily. (442 aa)
EFL87948.1Aspartate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. (539 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (375 aa)
aroK_2Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (205 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (423 aa)
EFL88113.1Glutamate dehydrogenase; Identified by match to protein family HMM PF05088. (1582 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (453 aa)
EFL89523.1Dihydrodipicolinate synthetase; Identified by match to protein family HMM PF00701; Belongs to the DapA family. (311 aa)
aroQ3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa)
EFL89564.1Chorismate mutase; Identified by match to protein family HMM PF01817; match to protein family HMM TIGR01795. (97 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (288 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (278 aa)
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (404 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Identified by match to protein family HMM PF00132; match to protein family HMM TIGR00965; Belongs to the transferase hexapeptide repeat family. (280 aa)
EFL87599.1Pyridine nucleotide-disulfide oxidoreductase family protein; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992. (443 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (274 aa)
folCIdentified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; chain A, Mycobacterium Tuberculosis Folylpolyglutamate Synthase Complexed With Adp. (438 aa)
EFL87736.1L-carnitine dehydratase/bile acid-inducible protein F; Identified by match to protein family HMM PF02515; Belongs to the CoA-transferase III family. (375 aa)
putAProline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1155 aa)
frc_2formyl-CoA transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily. (421 aa)
EFL87540.1L-carnitine dehydratase/bile acid-inducible protein F; Identified by match to protein family HMM PF02515; Belongs to the CoA-transferase III family. (397 aa)
folBDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (124 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. (167 aa)
EFL90197.1Identified by match to protein family HMM PF03937. (93 aa)
EFL90100.1Acyl carrier protein acpXL; Identified by match to protein family HMM PF00550. (91 aa)
folPDihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (281 aa)
EFL90490.1NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. (775 aa)
nadAQuinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (358 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (395 aa)
Your Current Organism:
Ahrensia sp. R2A130
NCBI taxonomy Id: 744979
Other names: A. sp. R2A130
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