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| | yeiN | Protein YeiN; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (304 aa) |
| | ispDF | Bifunctional enzyme IspD/ispF; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (392 aa) |
| | purB | Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (433 aa) |
| | EFL90161.1 | L-serine ammonia-lyase; Identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; Belongs to the iron-sulfur dependent L-serine dehydratase family. (471 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (424 aa) |
| | fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (155 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (161 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family. (267 aa) |
| | rlpA | Rare lipoprotein A protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (262 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family. (574 aa) |
| | EFL90317.1 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (491 aa) |
| | EFL90396.1 | Threo-3-hydroxyaspartate ammonia-lyase; Identified by match to protein family HMM PF00291. (325 aa) |
| | folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (124 aa) |
| | EFL90425.1 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (543 aa) |
| | EFL90451.1 | Citrate lyase subunit beta; Identified by match to protein family HMM PF03328; Belongs to the HpcH/HpaI aldolase family. (289 aa) |
| | EFL90479.1 | Deoxyribodipyrimidine photo-lyase family protein. (408 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. (348 aa) |
| | EFL90557.1 | O-acetylhomoserine (thiol)-lyase; Identified by match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01326. (426 aa) |
| | mltG | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (438 aa) |
| | psd | Putative phosphatidylserine decarboxylase-like protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (233 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa) |
| | EFL90674.1 | Threonine-phosphate decarboxylase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01140. (337 aa) |
| | itaE | Threonine aldolase; Identified by match to protein family HMM PF01212. (356 aa) |
| | EFL90859.1 | Deoxyribodipyrimidine photolyase. (324 aa) |
| | EFL88507.1 | Isocitrate lyase; Identified by match to protein family HMM PF00463. (530 aa) |
| | EFL88603.1 | Ureidoglycolate hydrolase. (160 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (165 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (364 aa) |
| | EFL88694.1 | Identified by match to protein family HMM PF04244. (505 aa) |
| | EFL88759.1 | Nitrile hydratase, beta subunit; NHase catalyzes the hydration of various nitrile compounds to the corresponding amides; Belongs to the nitrile hydratase subunit beta family. (226 aa) |
| | nthA | Nitrile hydratase, alpha subunit; Identified by match to protein family HMM PF02979; match to protein family HMM TIGR01323. (213 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (355 aa) |
| | ribB | Riboflavin biosynthesis protein ribBA, ic; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (382 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa) |
| | thrC | Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260. (466 aa) |
| | bchF | 2-vinyl bacteriochlorophyllide hydratase; Identified by match to protein family HMM PF07284; match to protein family HMM TIGR02020. (188 aa) |
| | EFL89132.1 | Lactoylglutathione lyase; Identified by match to protein family HMM PF00903. (146 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (375 aa) |
| | EFL88005.1 | Cation transport protein chac; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (193 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (423 aa) |
| | argH | Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838. (481 aa) |
| | EFL88248.1 | Carbonic anhydrase, ic; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (249 aa) |
| | EFL89523.1 | Dihydrodipicolinate synthetase; Identified by match to protein family HMM PF00701; Belongs to the DapA family. (311 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | EFL89560.1 | Putative pterin-4-alpha-carbinolamine dehydratase; Identified by match to protein family HMM PF01329. (104 aa) |
| | acnA | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (928 aa) |
| | EFL89684.1 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (233 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (342 aa) |
| | EFL89708.1 | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family. (604 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (213 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. (198 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (541 aa) |
| | ddc | aromatic-L-amino-acid decarboxylase; Identified by match to protein family HMM PF00282. (472 aa) |
| | fabA | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (169 aa) |
| | coaBC | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (408 aa) |
| | mutM | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (297 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (348 aa) |
| | EFL90999.1 | Anthranilate synthase; Identified by match to protein family HMM PF00117; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00566; match to protein family HMM TIGR01815. (718 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (232 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (405 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (274 aa) |
| | deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (252 aa) |
| | EFL88444.1 | Tagatose 1,6-diphosphate aldolase; Identified by match to protein family HMM PF01791. (342 aa) |
| | EFL88469.1 | Dihydrodipicolinate synthetase; Identified by match to protein family HMM PF00701; Belongs to the DapA family. (302 aa) |
| | EFL89257.1 | Conserved hypothetical protein; Identified by match to protein family HMM PF07286; Belongs to the D-glutamate cyclase family. (282 aa) |
| | metZ | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (392 aa) |
| | rlpA-2 | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (155 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (226 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (604 aa) |
| | EFL89245.1 | Cystathionine beta-lyase; Identified by match to protein family HMM PF01053. (375 aa) |
| | EFL87793.1 | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274; Belongs to the class I fructose-bisphosphate aldolase family. (341 aa) |
| | oxc | oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR03254; Belongs to the TPP enzyme family. (592 aa) |
