STRINGSTRING
AEX50248.1 AEX50248.1 AEX50441.1 AEX50441.1 AEX50564.1 AEX50564.1 queE queE AEX50611.1 AEX50611.1 queF queF AEX51185.1 AEX51185.1 AEX51338.1 AEX51338.1 folE folE AEX51663.1 AEX51663.1 ribA ribA AEX51950.1 AEX51950.1 AEX52743.1 AEX52743.1 AEX52785.1 AEX52785.1 AEX52800.1 AEX52800.1 AEX52929.1 AEX52929.1 moaC moaC AEX52932.1 AEX52932.1 moaA moaA queC queC AEX53539.1 AEX53539.1 AEX53645.1 AEX53645.1 AEX53670.1 AEX53670.1 mobA mobA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEX50248.1PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (191 aa)
AEX50441.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (279 aa)
AEX50564.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (118 aa)
queEOrganic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (223 aa)
AEX50611.1Queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. (119 aa)
queF7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). (281 aa)
AEX51185.1Folylpolyglutamate synthase/dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. (428 aa)
AEX51338.1Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (413 aa)
folEPFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. (221 aa)
AEX51663.1NTP pyrophosphohydrolase; PFAM: NUDIX domain. (148 aa)
ribAGTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. (196 aa)
AEX51950.1PFAM: Alkaline phosphatase; Belongs to the alkaline phosphatase family. (476 aa)
AEX52743.1PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. (458 aa)
AEX52785.1Putative MobA-like protein. (204 aa)
AEX52800.1Aminodeoxychorismate lyase; PFAM: Aminotransferase class IV; TIGRFAM: aminodeoxychorismate lyase. (265 aa)
AEX52929.1Molybdopterin converting factor, large subunit; PFAM: MoaE protein. (150 aa)
moaCMolybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (163 aa)
AEX52932.1Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (170 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (328 aa)
queCQueuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (232 aa)
AEX53539.1PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. (159 aa)
AEX53645.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (161 aa)
AEX53670.1PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (195 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A, proteobacterial; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (195 aa)
Your Current Organism:
Rahnella aquatilis
NCBI taxonomy Id: 745277
Other names: R. aquatilis CIP 78.65 = ATCC 33071, Rahnella aquatilis ATCC 33071, Rahnella aquatilis ATCC 33071 = CIP 78.65, Rahnella aquatilis CIP 78.65, Rahnella aquatilis CIP 78.65 = ATCC 33071, Rahnella aquatilis CUETM 77-115, Rahnella aquatilis CUETM 77-155, Rahnella aquatilis DSM 4594
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