STRINGSTRING
tusD tusD tusC tusC AEX50283.1 AEX50283.1 iscS iscS AEX51337.1 AEX51337.1 AEX51497.1 AEX51497.1 AEX52276.1 AEX52276.1 mnmA mnmA AEX52929.1 AEX52929.1 AEX52930.1 AEX52930.1 moaC moaC AEX52932.1 AEX52932.1 moaA moaA thiI thiI AEX53294.1 AEX53294.1 AEX53670.1 AEX53670.1 AEX53999.1 AEX53999.1 AEX54000.1 AEX54000.1 tusA tusA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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tusDSulfur relay protein TusD/DsrE; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. (130 aa)
tusCSulfur relay protein TusC/DsrF; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (119 aa)
AEX50283.1Sulfur relay protein TusB/DsrH; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (95 aa)
iscSCysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (389 aa)
AEX51337.1PFAM: MoeZ/MoeB domain; ThiF family; TIGRFAM: molybdopterin synthase sulfurylase MoeB. (253 aa)
AEX51497.1Sulfur relay protein, TusE/DsrC/DsvC family; Part of a sulfur-relay system. (109 aa)
AEX52276.1Rhodanese-related sulfurtransferase; PFAM: Rhodanese-like domain. (284 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family. (369 aa)
AEX52929.1Molybdopterin converting factor, large subunit; PFAM: MoaE protein. (150 aa)
AEX52930.1PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal. (81 aa)
moaCMolybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (163 aa)
AEX52932.1Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (170 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (328 aa)
thiIThiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (482 aa)
AEX53294.1Rhodanese-related sulfurtransferase; PFAM: Rhodanese-like domain. (281 aa)
AEX53670.1PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (195 aa)
AEX53999.1Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: MoeZ/MoeB domain; ThiF family. (249 aa)
AEX54000.1PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. (66 aa)
tusAPutative redox protein, regulator of disulfide bond formation; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the [...] (86 aa)
Your Current Organism:
Rahnella aquatilis
NCBI taxonomy Id: 745277
Other names: R. aquatilis CIP 78.65 = ATCC 33071, Rahnella aquatilis ATCC 33071, Rahnella aquatilis ATCC 33071 = CIP 78.65, Rahnella aquatilis CIP 78.65, Rahnella aquatilis CIP 78.65 = ATCC 33071, Rahnella aquatilis CUETM 77-115, Rahnella aquatilis CUETM 77-155, Rahnella aquatilis DSM 4594
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