STRINGSTRING
AEE13800.1 AEE13800.1 AEE13863.1 AEE13863.1 AEE13871.1 AEE13871.1 AEE13887.1 AEE13887.1 AEE13888.1 AEE13888.1 glmU glmU murA murA lgt lgt mraZ mraZ rsmH rsmH AEE14293.1 AEE14293.1 AEE14294.1 AEE14294.1 murE murE AEE14296.1 AEE14296.1 mraY mraY murD murD AEE14299.1 AEE14299.1 murG murG murC murC murB murB ddl ddl AEE14304.1 AEE14304.1 AEE14305.1 AEE14305.1 AEE14306.1 AEE14306.1 AEE14307.1 AEE14307.1 ftsZ ftsZ AEE14309.1 AEE14309.1 AEE14310.1 AEE14310.1 AEE14312.1 AEE14312.1 mltG mltG AEE14314.1 AEE14314.1 AEE14315.1 AEE14315.1 AEE14316.1 AEE14316.1 AEE14317.1 AEE14317.1 AEE14318.1 AEE14318.1 minC minC AEE14320.1 AEE14320.1 minE minE AEE14322.1 AEE14322.1 AEE14323.1 AEE14323.1 AEE14325.1 AEE14325.1 AEE14326.1 AEE14326.1 AEE14329.1 AEE14329.1 AEE14330.1 AEE14330.1 AEE14331.1 AEE14331.1 AEE14336.1 AEE14336.1 AEE14337.1 AEE14337.1 AEE14341.1 AEE14341.1 AEE14849.1 AEE14849.1 AEE15214.1 AEE15214.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
AEE13800.1COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846:IPR005843; KEGG: oih:OB0232 phosphoglucomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; PRIAM: Phosphoglucosamine mutase; SPTR: Phosphoglucosamine mutase; IMG reference gene:2504783516; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/pho [...] (438 aa)
AEE13863.1COGs: COG0728 membrane protein putative virulence factor; InterPro IPR004268; KEGG: cst:CLOST_0370 integral membrane protein MviN; PFAM: Flagellin assembly, membrane protein MviN; SPTR: Integral membrane protein MviN; IMG reference gene:2504783580; PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN. (511 aa)
AEE13871.1COGs: COG1355 dioxygenase; InterPro IPR002737; KEGG: dth:DICTH_1399 hypothetical protein; PFAM: UPF0103/Mediator of ErbB2-driven cell motility (Memo), related; SPTR: Conserved protein; IMG reference gene:2504783589; PFAM: Memo-like protein; Belongs to the MEMO1 family. (264 aa)
AEE13887.1GTP-binding protein TypA; COGs: COG1217 membrane GTPase involved in stress response; InterProIPR005225:IPR006298:IPR000795:IPR004161:IPR 000640; KEGG: vpr:Vpar_1324 GTP-binding protein TypA; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; SPTR: GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; IMG reference gene:2504783607; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-bindin [...] (597 aa)
AEE13888.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (352 aa)
glmUBifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (461 aa)
murAUDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (405 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (249 aa)
mraZProtein mraZ; COGs: COG2001 conserved hypothetical protein; HAMAP: MraZ; InterPro IPR020603:IPR003444; KEGG: csc:Csac_0916 cell division protein MraZ; PFAM: MraZ domain; SPTR: Protein MraZ; TIGRFAM: MraZ; IMG reference gene:2504784037; PFAM: MraZ protein; TIGRFAM: mraZ protein; Belongs to the MraZ family. (138 aa)
rsmHRibosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (298 aa)
AEE14293.1Hypothetical protein; IMG reference gene:2504784039. (116 aa)
AEE14294.1Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. (539 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (487 aa)
AEE14296.1UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. (477 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (313 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (464 aa)
AEE14299.1Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: cbs:COXBURSA331_A0222 cell division protein FtsW; PFAM: Cell cycle protein; SPTR: Stage V sporulation protein E; IMG reference gene:2504784045; PFAM: Cell cycle protein; Belongs to the SEDS family. (367 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (360 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (478 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (295 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (308 aa)
AEE14304.1Hypothetical protein; IMG reference gene:2504784050. (223 aa)
AEE14305.1Protein of unknown function DUF881; COGs: COG3879 conserved hypothetical protein; InterPro IPR010273; KEGG: toc:Toce_0956 protein of unknown function DUF881; PFAM: Protein of unknown function DUF881, bacterial; SPTR: Putative uncharacterized protein; IMG reference gene:2504784051; PFAM: Bacterial protein of unknown function (DUF881). (254 aa)
AEE14306.1Protein of unknown function DUF1290; COGs: COG3856 conserved hypothetical protein (small basic protein); InterPro IPR009709; KEGG: mta:Moth_0848 hypothetical protein; PFAM: Protein of unknown function DUF1290; SPTR: Putative uncharacterized protein; IMG reference gene:2504784052; PFAM: Protein of unknown function (DUF1290). (115 aa)
AEE14307.1Cell division protein FtsA; COGs: COG0849 Actin-like ATPase involved in cell division; InterPro IPR003494:IPR020823; KEGG: aae:aq_523 cell division protein FtsA; PFAM: Cell division protein FtsA domain; SPTR: Cell division protein FtsA; TIGRFAM: Cell division protein family FtsA; IMG reference gene:2504784053; PFAM: Cell division protein FtsA; TIGRFAM: cell division protein FtsA. (383 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (361 aa)
AEE14309.1Hypothetical protein; IMG reference gene:2504784055. (329 aa)
AEE14310.1COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: aco:Amico_0841 cell envelope-related transcriptional attenuator; PFAM: Cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related transcriptional attenuator; TIGRFAM: Cell envelope-related transcriptional attenuator; IMG reference gene:2504784056; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. (394 aa)
AEE14312.1KEGG: hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504784058; PFAM: Protein of unknown function (DUF1292). (108 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (329 aa)
AEE14314.1Sporulation domain-containing protein; InterPro IPR007730; PFAM: Sporulation/cell division region, bacteria; IMG reference gene:2504784060; PFAM: Sporulation related domain. (179 aa)
AEE14315.1Cell shape determining protein, MreB/Mrl family; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: rod shape-determining protein MreB; PFAM: Cell shape determining protein MreB/Mrl; SPTR: Rod shape-determining protein MreB; TIGRFAM: Cell shape determining protein MreB/Mrl; IMG reference gene:2504784061; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family. (337 aa)
AEE14316.1COGs: COG1792 Cell shape-determining protein; InterPro IPR007221; KEGG: pmx:PERMA_0056 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein MreC; IMG reference gene:2504784062; PFAM: rod shape-determining protein MreC. (266 aa)
AEE14317.1Hypothetical protein; IMG reference gene:2504784063. (164 aa)
AEE14318.1Penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR017790; KEGG: dtu:Dtur_1401 penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2; IMG reference gene:2504784064; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2. (567 aa)
minCSeptum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (225 aa)
AEE14320.1Septum site-determining protein MinD; COGs: COG2894 Septum formation inhibitor-activating ATPase; InterPro IPR002586:IPR010223; KEGG: ctc:CTC02069 septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Septum site-determining protein MinD; TIGRFAM: Septum site-determining protein MinD; IMG reference gene:2504784066; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: septum site-determining protein MinD. (269 aa)
minECell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (84 aa)
AEE14322.1Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: dap:Dacet_1268 rod shape-determining protein RodA; PFAM: Cell cycle protein; SPTR: Rod shape-determining protein RodA; IMG reference gene:2504784068; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. (412 aa)
AEE14323.1Protein of unknown function DUF6 transmembrane; InterPro IPR000620; KEGG: tsi:TSIB_1760 permease, drug/metabolite transporter (DMT) superfamily; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Permease, drug/metabolite transporter (DMT) superfamily; IMG reference gene:2504784069; PFAM: EamA-like transporter family. (297 aa)
AEE14325.1AMMECR1 domain protein; COGs: COG2078 conserved hypothetical protein; InterPro IPR002733; KEGG: pmo:Pmob_1459 AMMECR1 domain-containing protein; PFAM: AMMECR1; SPTR: AMMECR1 domain protein; IMG reference gene:2504784071; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family. (168 aa)
AEE14326.1Hypothetical protein; IMG reference gene:2504784072; PFAM: NTF2-like N-terminal transpeptidase domain. (159 aa)
AEE14329.1InterPro IPR003825; PFAM: Colicin V production protein; IMG reference gene:2504784075. (164 aa)
AEE14330.1PHP domain protein; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013:IPR003141; KEGG: hor:Hore_05670 DNA polymerase X family protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase X family protein; IMG reference gene:2504784076; PFAM: PHP domain. (573 aa)
AEE14331.1Hypothetical protein; IMG reference gene:2504784077. (151 aa)
AEE14336.1Nucleoside diphosphate pyrophosphatase; InterPro IPR000086:IPR004385; KEGG: amt:Amet_2521 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase; TIGRFAM: Nucleoside diphosphate pyrophosphatase; IMG reference gene:2504784082; PFAM: NUDIX domain; TIGRFAM: nudix-type nucleoside diphosphatase, YffH/AdpP family; Belongs to the Nudix hydrolase family. (176 aa)
AEE14337.1Tyrosine recombinase xerC; COGs: COG4974 Site-specific recombinase XerD; HAMAP: Tyrosine recombinase xerC; InterPro IPR004107:IPR002104; KEGG: dtu:Dtur_1473 tyrosine recombinase XerD; PFAM: Integrase, catalytic core, phage; Integrase, N-terminal SAM-like, phage; SPTR: Tyrosine recombinase XerD; IMG reference gene:2504784083; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; Belongs to the 'phage' integrase family. (306 aa)
AEE14341.1Hypothetical protein; IMG reference gene:2504784089. (62 aa)
AEE14849.1Radical SAM domain protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197; KEGG: mfv:Mfer_0959 radical sam domain protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; IMG reference gene:2504784638; PFAM: Radical SAM superfamily. (338 aa)
AEE15214.1COGs: COG1164 Oligoendopeptidase F; InterPro IPR004438:IPR013647:IPR001567; KEGG: tte:TTE1010 oligoendopeptidase F; PFAM: Peptidase M3A/M3B, thimet/oligopeptidase F; Peptidase M3B, oligopeptidase F, N-terminal; SPTR: Oligoendopeptidase F; TIGRFAM: Peptidase M3B, oligoendopeptidase F; IMG reference gene:2504785020; PFAM: Oligopeptidase F; Peptidase family M3; TIGRFAM: oligoendopeptidase F. (593 aa)
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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