node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEE14294.1 | AEE14296.1 | Thena_0659 | Thena_0661 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | 0.933 |
AEE14294.1 | AEE14299.1 | Thena_0659 | Thena_0664 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: cbs:COXBURSA331_A0222 cell division protein FtsW; PFAM: Cell cycle protein; SPTR: Stage V sporulation protein E; IMG reference gene:2504784045; PFAM: Cell cycle protein; Belongs to the SEDS family. | 0.968 |
AEE14294.1 | AEE14307.1 | Thena_0659 | Thena_0672 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | Cell division protein FtsA; COGs: COG0849 Actin-like ATPase involved in cell division; InterPro IPR003494:IPR020823; KEGG: aae:aq_523 cell division protein FtsA; PFAM: Cell division protein FtsA domain; SPTR: Cell division protein FtsA; TIGRFAM: Cell division protein family FtsA; IMG reference gene:2504784053; PFAM: Cell division protein FtsA; TIGRFAM: cell division protein FtsA. | 0.713 |
AEE14294.1 | ddl | Thena_0659 | Thena_0668 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.821 |
AEE14294.1 | ftsZ | Thena_0659 | Thena_0673 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.727 |
AEE14294.1 | mraY | Thena_0659 | Thena_0662 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.977 |
AEE14294.1 | murB | Thena_0659 | Thena_0667 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.702 |
AEE14294.1 | murC | Thena_0659 | Thena_0666 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.883 |
AEE14294.1 | murD | Thena_0659 | Thena_0663 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.946 |
AEE14294.1 | murE | Thena_0659 | Thena_0660 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.958 |
AEE14294.1 | murG | Thena_0659 | Thena_0665 | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.872 |
AEE14296.1 | AEE14294.1 | Thena_0661 | Thena_0659 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504784040; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | 0.933 |
AEE14296.1 | AEE14299.1 | Thena_0661 | Thena_0664 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: cbs:COXBURSA331_A0222 cell division protein FtsW; PFAM: Cell cycle protein; SPTR: Stage V sporulation protein E; IMG reference gene:2504784045; PFAM: Cell cycle protein; Belongs to the SEDS family. | 0.948 |
AEE14296.1 | AEE14307.1 | Thena_0661 | Thena_0672 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | Cell division protein FtsA; COGs: COG0849 Actin-like ATPase involved in cell division; InterPro IPR003494:IPR020823; KEGG: aae:aq_523 cell division protein FtsA; PFAM: Cell division protein FtsA domain; SPTR: Cell division protein FtsA; TIGRFAM: Cell division protein family FtsA; IMG reference gene:2504784053; PFAM: Cell division protein FtsA; TIGRFAM: cell division protein FtsA. | 0.872 |
AEE14296.1 | ddl | Thena_0661 | Thena_0668 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.998 |
AEE14296.1 | ftsZ | Thena_0661 | Thena_0673 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.855 |
AEE14296.1 | mraY | Thena_0661 | Thena_0662 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.998 |
AEE14296.1 | murB | Thena_0661 | Thena_0667 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.964 |
AEE14296.1 | murC | Thena_0661 | Thena_0666 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.983 |
AEE14296.1 | murD | Thena_0661 | Thena_0663 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.993 |