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AEE13702.1 AEE13702.1 AEE13993.1 AEE13993.1 AEE14227.1 AEE14227.1 AEE14487.1 AEE14487.1 AEE14558.1 AEE14558.1 AEE14576.1 AEE14576.1 AEE14577.1 AEE14577.1 AEE14658.1 AEE14658.1 AEE14687.1 AEE14687.1 AEE14699.1 AEE14699.1 AEE14700.1 AEE14700.1 AEE14706.1 AEE14706.1 AEE14707.1 AEE14707.1 AEE14708.1 AEE14708.1 AEE15042.1 AEE15042.1 AEE15043.1 AEE15043.1 AEE15044.1 AEE15044.1 AEE15185.1 AEE15185.1 AEE15186.1 AEE15186.1 AEE15242.1 AEE15242.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
AEE13702.1D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: dps:DP0059 glycolate oxidase subunit (GlcD); PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Glycolate oxidase subunit glcD; IMG reference gene:2504783413; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. (764 aa)
AEE13993.1COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: ppd:Ppro_2915 glycerate kinase; PFAM: Glycerate kinase; PRIAM: Glycerate kinase; SPTR: Glycerate kinase; TIGRFAM: Glycerate kinase; IMG reference gene:2504783724; PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family. (390 aa)
AEE14227.1Protein of unknown function DUF1121; InterPro IPR009501; KEGG: cno:NT01CX_1623 hypothetical protein; PFAM: Protein of unknown function DUF1121; SPTR: Putative uncharacterized protein; IMG reference gene:2504783970; PFAM: Uncharacterised ACR, YkgG family COG1556. (213 aa)
AEE14487.1D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: dhd:Dhaf_4518 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Putative uncharacterized protein; IMG reference gene:2504784250; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. (467 aa)
AEE14558.1Glyoxylate reductase; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: bmd:BMD_3518 glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; PRIAM: Glyoxylate reductase; SPTR: Glyoxylate reductase; IMG reference gene:2504784324; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (322 aa)
AEE14576.1Lactate utilization protein B/C; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: dba:Dbac_1728 protein of unknown function DUF162; PFAM: Protein of unknown function DUF162; SPTR: Putative uncharacterized protein; IMG reference gene:2504784344; PFAM: Uncharacterised ACR, YkgG family COG1556. (139 aa)
AEE14577.1Lactate utilization protein B/C; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR003741:IPR004017; KEGG: tye:THEYE_A0665 iron-sulfur cluster-binding protein; PFAM: Protein of unknown function DUF162; Cysteine-rich region, CCG; SPTR: Iron-sulfur cluster-binding protein; IMG reference gene:2504784345; PFAM: Cysteine-rich domain; Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein. (674 aa)
AEE14658.1HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG0546 phosphatase; InterPro IPR006439:IPR005834; KEGG: dal:Dalk_1233 HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase-like hydrolase; PRIAM: Phosphoglycolate phosphatase; SPTR: Similar to phosphoglycolate phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; IMG reference gene:2504784426; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. (222 aa)
AEE14687.12-hydroxy-3-oxopropionate reductase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: rcu:RCOM_1211530 3-hydroxyisobutyrate dehydrogenase, putative; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: Putative uncharacterized protein; IMG reference gene:2504784463; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. (285 aa)
AEE14699.1Lactate utilization protein B/C; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR003741:IPR001450:IPR004017; KEGG: hmo:HM1_0363 4fe-4S ferredoxin, iron-sulfur binding protein, putative; PFAM: Protein of unknown function DUF162; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Cysteine-rich region, CCG; SPTR: Putative uncharacterized protein; IMG reference gene:2504784476; PFAM: Cysteine-rich domain; Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein. (722 aa)
AEE14700.1Lactate utilization protein B/C; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: drm:Dred_0689 hypothetical protein; PFAM: Protein of unknown function DUF162; SPTR: Putative uncharacterized protein; IMG reference gene:2504784477; PFAM: Uncharacterised ACR, YkgG family COG1556. (193 aa)
AEE14706.1Anaerobic ribonucleoside-triphosphate reductase activating protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR012840:IPR007197; KEGG: hor:Hore_11040 anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM; SPTR: Anaerobic ribonucleoside-triphosphate reductase activating protein; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic-like; IMG reference gene:2504784483; PFAM: Radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein. (229 aa)
AEE14707.1COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR012833:IPR005144; KEGG: hya:HY04AAS1_1401 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone; PRIAM: Ribonucleoside-triphosphate reductase; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; IMG reference gene:2504784484; PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. (758 aa)
AEE14708.1Putative transcriptional regulator, GntR family; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: aminotransferase; PFAM: Aminotransferase, class I/II; SPTR: Putative transcriptional regulator, GntR family; IMG reference gene:2504784485; PFAM: Aminotransferase class I and II. (389 aa)
AEE15042.1D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: chy:CHY_0432 putative glycolate oxidase, GlcD subunit; PFAM: FAD linked oxidase, N-terminal; FAD-linked oxidase, C-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Putative glycolate oxidase, GlcD subunit; IMG reference gene:2504784838; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain. (413 aa)
AEE15043.14Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR001450:IPR004017; KEGG: aar:Acear_1800 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Cysteine-rich region, CCG; SPTR: Putative uncharacterized protein; IMG reference gene:2504784839; PFAM: Cysteine-rich domain. (435 aa)
AEE15044.1D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: dhd:Dhaf_4518 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Putative uncharacterized protein; IMG reference gene:2504784840; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. (468 aa)
AEE15185.1L-lactate permease, putative; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (533 aa)
AEE15186.1L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (564 aa)
AEE15242.1(S)-2-hydroxy-acid oxidase; COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262; KEGG: drm:Dred_1257 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase; PRIAM: (S)-2-hydroxy-acid oxidase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; IMG reference gene:2504785048; PFAM: FMN-dependent dehydrogenase. (339 aa)
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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