node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEE13836.1 | AEE14858.1 | Thena_0187 | Thena_1239 | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: aco:Amico_1280 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504783553; PFAM: Sir2 family. | CinA domain protein; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008136:IPR001453; KEGG: tme:Tmel_0783 competence/damage-inducible protein CinA; PFAM: Molybdopterin binding; CinA, C-terminal; SPTR: CinA-like protein; TIGRFAM: CinA, C-terminal; IMG reference gene:2504784648; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain. | 0.510 |
AEE13836.1 | nadD | Thena_0187 | Thena_1358 | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: aco:Amico_1280 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504783553; PFAM: Sir2 family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.924 |
AEE13836.1 | nadE | Thena_0187 | Thena_1000 | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: aco:Amico_1280 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504783553; PFAM: Sir2 family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.962 |
AEE13836.1 | nadK | Thena_0187 | Thena_0996 | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: aco:Amico_1280 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504783553; PFAM: Sir2 family. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.915 |
AEE14813.1 | AEE14858.1 | Thena_1194 | Thena_1239 | HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402:IPR005834; KEGG: tye:THEYE_A1877 HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504784602; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | CinA domain protein; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008136:IPR001453; KEGG: tme:Tmel_0783 competence/damage-inducible protein CinA; PFAM: Molybdopterin binding; CinA, C-terminal; SPTR: CinA-like protein; TIGRFAM: CinA, C-terminal; IMG reference gene:2504784648; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain. | 0.940 |
AEE14813.1 | AEE15137.1 | Thena_1194 | Thena_1525 | HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402:IPR005834; KEGG: tye:THEYE_A1877 HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504784602; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR002638; KEGG: tba:TERMP_01329 nicotinate phosphoribosyltransferase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate phosphoribosyltransferase; SPTR: Quinolinate phosphoribosyl transferase, C-terminal domain protein; IMG reference gene:2504784938; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: putative nicotinate phosphoribosyltransferase. | 0.910 |
AEE14813.1 | nadD | Thena_1194 | Thena_1358 | HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402:IPR005834; KEGG: tye:THEYE_A1877 HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504784602; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.923 |
AEE14813.1 | nadE | Thena_1194 | Thena_1000 | HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402:IPR005834; KEGG: tye:THEYE_A1877 HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504784602; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.650 |
AEE14858.1 | AEE13836.1 | Thena_1239 | Thena_0187 | CinA domain protein; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008136:IPR001453; KEGG: tme:Tmel_0783 competence/damage-inducible protein CinA; PFAM: Molybdopterin binding; CinA, C-terminal; SPTR: CinA-like protein; TIGRFAM: CinA, C-terminal; IMG reference gene:2504784648; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain. | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: aco:Amico_1280 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504783553; PFAM: Sir2 family. | 0.510 |
AEE14858.1 | AEE14813.1 | Thena_1239 | Thena_1194 | CinA domain protein; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008136:IPR001453; KEGG: tme:Tmel_0783 competence/damage-inducible protein CinA; PFAM: Molybdopterin binding; CinA, C-terminal; SPTR: CinA-like protein; TIGRFAM: CinA, C-terminal; IMG reference gene:2504784648; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain. | HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402:IPR005834; KEGG: tye:THEYE_A1877 HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504784602; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | 0.940 |
AEE14858.1 | AEE15137.1 | Thena_1239 | Thena_1525 | CinA domain protein; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008136:IPR001453; KEGG: tme:Tmel_0783 competence/damage-inducible protein CinA; PFAM: Molybdopterin binding; CinA, C-terminal; SPTR: CinA-like protein; TIGRFAM: CinA, C-terminal; IMG reference gene:2504784648; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain. | COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR002638; KEGG: tba:TERMP_01329 nicotinate phosphoribosyltransferase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate phosphoribosyltransferase; SPTR: Quinolinate phosphoribosyl transferase, C-terminal domain protein; IMG reference gene:2504784938; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: putative nicotinate phosphoribosyltransferase. | 0.973 |
AEE14858.1 | nadD | Thena_1239 | Thena_1358 | CinA domain protein; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008136:IPR001453; KEGG: tme:Tmel_0783 competence/damage-inducible protein CinA; PFAM: Molybdopterin binding; CinA, C-terminal; SPTR: CinA-like protein; TIGRFAM: CinA, C-terminal; IMG reference gene:2504784648; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.978 |
AEE14858.1 | nadE | Thena_1239 | Thena_1000 | CinA domain protein; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008136:IPR001453; KEGG: tme:Tmel_0783 competence/damage-inducible protein CinA; PFAM: Molybdopterin binding; CinA, C-terminal; SPTR: CinA-like protein; TIGRFAM: CinA, C-terminal; IMG reference gene:2504784648; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.773 |
AEE14858.1 | nadK | Thena_1239 | Thena_0996 | CinA domain protein; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008136:IPR001453; KEGG: tme:Tmel_0783 competence/damage-inducible protein CinA; PFAM: Molybdopterin binding; CinA, C-terminal; SPTR: CinA-like protein; TIGRFAM: CinA, C-terminal; IMG reference gene:2504784648; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.459 |
AEE15137.1 | AEE14813.1 | Thena_1525 | Thena_1194 | COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR002638; KEGG: tba:TERMP_01329 nicotinate phosphoribosyltransferase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate phosphoribosyltransferase; SPTR: Quinolinate phosphoribosyl transferase, C-terminal domain protein; IMG reference gene:2504784938; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: putative nicotinate phosphoribosyltransferase. | HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402:IPR005834; KEGG: tye:THEYE_A1877 HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504784602; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | 0.910 |
AEE15137.1 | AEE14858.1 | Thena_1525 | Thena_1239 | COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR002638; KEGG: tba:TERMP_01329 nicotinate phosphoribosyltransferase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate phosphoribosyltransferase; SPTR: Quinolinate phosphoribosyl transferase, C-terminal domain protein; IMG reference gene:2504784938; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: putative nicotinate phosphoribosyltransferase. | CinA domain protein; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008136:IPR001453; KEGG: tme:Tmel_0783 competence/damage-inducible protein CinA; PFAM: Molybdopterin binding; CinA, C-terminal; SPTR: CinA-like protein; TIGRFAM: CinA, C-terminal; IMG reference gene:2504784648; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain. | 0.973 |
AEE15137.1 | nadD | Thena_1525 | Thena_1358 | COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR002638; KEGG: tba:TERMP_01329 nicotinate phosphoribosyltransferase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate phosphoribosyltransferase; SPTR: Quinolinate phosphoribosyl transferase, C-terminal domain protein; IMG reference gene:2504784938; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: putative nicotinate phosphoribosyltransferase. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.959 |
AEE15137.1 | nadE | Thena_1525 | Thena_1000 | COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR002638; KEGG: tba:TERMP_01329 nicotinate phosphoribosyltransferase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate phosphoribosyltransferase; SPTR: Quinolinate phosphoribosyl transferase, C-terminal domain protein; IMG reference gene:2504784938; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: putative nicotinate phosphoribosyltransferase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.768 |
nadD | AEE13836.1 | Thena_1358 | Thena_0187 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: aco:Amico_1280 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504783553; PFAM: Sir2 family. | 0.924 |
nadD | AEE14813.1 | Thena_1358 | Thena_1194 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402:IPR005834; KEGG: tye:THEYE_A1877 HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504784602; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | 0.923 |