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AEE13680.1 AEE13680.1 AEE13739.1 AEE13739.1 AEE13814.1 AEE13814.1 AEE13833.1 AEE13833.1 AEE13876.1 AEE13876.1 thrB thrB AEE13878.1 AEE13878.1 AEE13881.1 AEE13881.1 prs prs coaX coaX AEE13921.1 AEE13921.1 ppk ppk AEE13993.1 AEE13993.1 AEE14066.1 AEE14066.1 pgk pgk thiL thiL AEE14180.1 AEE14180.1 AEE14249.1 AEE14249.1 AEE14376.1 AEE14376.1 tmk tmk cmk cmk gmk gmk AEE14464.1 AEE14464.1 AEE14528.1 AEE14528.1 AEE14584.1 AEE14584.1 nadK nadK argB argB AEE14838.1 AEE14838.1 AEE14884.1 AEE14884.1 eno eno coaE coaE AEE14911.1 AEE14911.1 AEE14912.1 AEE14912.1 pyrH pyrH proB proB lpxK lpxK AEE15017.1 AEE15017.1 AEE15078.1 AEE15078.1 AEE15102.1 AEE15102.1 AEE15103.1 AEE15103.1 AEE15113.1 AEE15113.1 ispE ispE selD selD AEE15175.1 AEE15175.1 AEE15197.1 AEE15197.1 adk adk pgk-2 pgk-2 AEE15239.1 AEE15239.1 gpmI gpmI aroK aroK AEE15282.1 AEE15282.1 AEE15314.1 AEE15314.1 AEE15377.1 AEE15377.1 AEE15381.1 AEE15381.1 thiM thiM ndk ndk
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AEE13680.1CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR010808:IPR004105:IPR003594:IPR 002545; KEGG: mta:Moth_0742 CheA signal transduction histidine kinases; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, P2 response regulator-binding; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, subgroup, homodimeric; CheW-like protein; SMART: Signal transduction histidine kinase, phosphotransfer (Hpt) region; ATP-binding region, ATPa [...] (682 aa)
AEE13739.1polyphosphate:AMP phosphotransferase; COGs: COG2326 conserved hypothetical protein; InterPro IPR005660; KEGG: csh:Closa_0956 protein of unknown function DUF344; PFAM: Polyphosphate kinase 2; SPTR: Putative uncharacterized protein; TIGRFAM: polyphosphate:AMP phosphotransferase; IMG reference gene:2504783451; PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate:AMP phosphotransferase. (491 aa)
AEE13814.1Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (182 aa)
AEE13833.1Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: dtu:Dtur_1236 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; SPTR: PAS/PAC sensor signal transduction histidine kinase; IMG reference gene:2504783550; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A [...] (301 aa)
AEE13876.1Phosphonopyruvate decarboxylase-related protein; COGs: COG3635 phosphoglycerate mutase AP superfamily; InterPro IPR004456:IPR019304:IPR006124; KEGG: gbm:Gbem_1879 cofactor-independent phosphoglycerate mutase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme; PRIAM: Phosphoglycerate mutase; SPTR: Proposed homoserine kinase; TIGRFAM: Cofactor-independent phosphoglycerate mutase, archaeal; IMG reference gene:2504783594; PFAM: Metalloenzyme superfamily; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: 2,3-bisphosphoglycerate-independent [...] (383 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (285 aa)
AEE13878.1COGs: COG0527 Aspartokinase; InterPro IPR005260:IPR001341:IPR001048:IPR002912; KEGG: adg:Adeg_0884 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; Aspartate kinase, monofunctional class; IMG reference gene:2504783596; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (410 aa)
AEE13881.11-phosphofructokinase; COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR017583:IPR011611; KEGG: mtp:Mthe_0686 1-phosphofructokinase; PFAM: Carbohydrate/purine kinase; PRIAM: 1-phosphofructokinase; SPTR: 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; IMG reference gene:2504783600; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family. (309 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (314 aa)
coaXPutative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (275 aa)
AEE13921.1Uncharacterized protein family UPF0079, ATPase; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: fno:Fnod_0408 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria; IMG reference gene:2504783643; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family. (148 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (721 aa)
AEE13993.1COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: ppd:Ppro_2915 glycerate kinase; PFAM: Glycerate kinase; PRIAM: Glycerate kinase; SPTR: Glycerate kinase; TIGRFAM: Glycerate kinase; IMG reference gene:2504783724; PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family. (390 aa)
AEE14066.1Phosphoribulokinase; COGs: COG0572 Uridine kinase; InterPro IPR006083; KEGG: adg:Adeg_1862 phosphoribulokinase/uridine kinase; PFAM: Phosphoribulokinase/uridine kinase; PRIAM: Phosphoribulokinase; SPTR: Phosphoribulokinase/uridine kinase; IMG reference gene:2504783802; PFAM: Phosphoribulokinase / Uridine kinase family. (298 aa)
pgkCOGs: COG0126 3-phosphoglycerate kinase; HAMAP: Phosphoglycerate kinase; InterPro IPR001576; KEGG: chy:CHY_0281 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; IMG reference gene:2504783806; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (401 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (327 aa)
AEE14180.1COGs: COG2187 conserved hypothetical protein; KEGG: tye:THEYE_A1962 Uma3; SPTR: Uma3; IMG reference gene:2504783919; PFAM: Zeta toxin. (517 aa)
AEE14249.1Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR002606:IPR015864:IPR015865; KEGG: mtt:Ftrac_0781 riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Cytidyltransferase-related; IMG reference gene:2504783992; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (307 aa)
AEE14376.1PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: PfkB domain protein; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein; IMG reference gene:2504784128; PFAM: pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (318 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (214 aa)
cmkCOGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR000623:IPR011994:IPR003136; KEGG: taf:THA_1828 cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; IMG reference gene:2504784156; PFAM: Cytidylate kinase; Shikimate kinase; TIGRFAM: cytidylate kinase. (224 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (215 aa)
AEE14464.1COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003852; KEGG: hya:HY04AAS1_0720 osmosensitive K channel His kinase sensor; PFAM: Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal; SPTR: Osmosensitive K channel His kinase sensor; IMG reference gene:2504784225; PFAM: Universal stress protein family; Osmosensitive K+ channel His kinase sensor domain. (644 aa)
AEE14528.1Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: cni:Calni_1776 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504784292; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (297 aa)
AEE14584.1COGs: COG3920 Signal transduction histidine kinase; InterPro IPR011495:IPR003594; KEGG: str:Sterm_1052 signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; ATP-binding region, ATPase-like; SPTR: Signal transduction histidine kinase; IMG reference gene:2504784352; PFAM: Histidine kinase. (416 aa)
nadKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (265 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (288 aa)
AEE14838.1COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015794:IPR008279; KEGG: tjr:TherJR_2325 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region; PRIAM: Pyruvate kinase., Pyruvate, water dikinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; IMG reference gene:2504784627; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase. (583 aa)
AEE14884.1Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: nis:NIS_0636 hypothetical protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase (GGDEF domain); TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504784675; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (337 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa)
AEE14911.1Cytidyltransferase-related domain protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (155 aa)
AEE14912.1rfaE bifunctional protein; COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR011913:IPR011611; KEGG: ddf:DEFDS_0511 ADP-heptose synthase; PFAM: Carbohydrate/purine kinase; SPTR: ADP-heptose synthase; TIGRFAM: RfaE bifunctional protein, domain I; IMG reference gene:2504784704; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I. (340 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (234 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (360 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (356 aa)
AEE15017.1Glucokinase; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: dth:DICTH_0734 glucokinase; PFAM: ROK; PRIAM: Glucokinase; SPTR: Glucokinase; IMG reference gene:2504784813; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase). (336 aa)
AEE15078.1COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR003660; KEGG: cni:Calni_0141 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504784877; PFAM: HAMP domain; Histidine kinase-, DNA g [...] (441 aa)
AEE15102.1Pyruvate, phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR010121:IPR002192:IPR008279:IPR000121; KEGG: chy:CHY_0443 pyruvate phosphate dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; PEP-utilising enzyme; PRIAM: Pyruvate, phosphate dikinase; SPTR: Pyruvate, phosphate dikinase; TIGRFAM: Pyruvate, phosphate dikinase; IMG reference gene:2504784901; PFAM: PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; Pyruvate phosphate dikinase, PEP/pyruvate binding [...] (883 aa)
AEE15103.1Phosphotransferase ydiA; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (270 aa)
AEE15113.1COGs: COG0818 Diacylglycerol kinase; InterPro IPR000829; KEGG: cow:Calow_1066 diacylglycerol kinase; PFAM: Diacylglycerol kinase, prokaryotic; SPTR: Diacylglycerol kinase; IMG reference gene:2504784912; PFAM: Prokaryotic diacylglycerol kinase. (134 aa)
ispE4-diphosphocytidyl-2-C-methyl-D- erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (276 aa)
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (353 aa)
AEE15175.1COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003660:IPR011712:IPR003594; KEGG: nth:Nther_0649 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region; HAMP linker domain; ATP-binding region, ATPase-like; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504784976; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (465 aa)
AEE15197.1Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: sat:SYN_00248 cyclic nucleotide-binding domain-containing protein; PFAM: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp; SMART: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp; SPTR: Putative uncharacterized protein; IMG reference gene:2504785002; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. (221 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa)
pgk-2COGs: COG0126 3-phosphoglycerate kinase; HAMAP: Phosphoglycerate kinase; InterPro IPR001576; KEGG: tnp:Tnap_0485 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; IMG reference gene:2504785044; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (396 aa)
AEE15239.1COGs: COG0149 Triosephosphate isomerase; InterPro IPR000652; KEGG: aae:aq_360 triosephosphate isomerase; PFAM: Triosephosphate isomerase; PRIAM: Triose-phosphate isomerase; SPTR: Triosephosphate isomerase; TIGRFAM: Triosephosphate isomerase; IMG reference gene:2504785045; PFAM: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase. (232 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (501 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (174 aa)
AEE15282.1COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003660:IPR003594; KEGG: ATPase ATP-binding domain-containing protein; PFAM: ATP-binding region, ATPase-like; HAMP linker domain; SMART: HAMP linker domain; ATP-binding region, ATPase-like; SPTR: Histidine kinase; IMG reference gene:2504785088; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (468 aa)
AEE15314.1COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: tte:TTE1017 sensory transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SPTR: Sensory transduction histidine kinases; IMG reference gene:2504785121; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPas [...] (458 aa)
AEE15377.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: bld:BLi00095 hypothetical protein; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine); TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; IMG reference gene:2504785187; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyroph [...] (168 aa)
AEE15381.1ABC-1 domain-containing protein; COGs: COG0661 unusual protein kinase; InterPro IPR004147; KEGG: gur:Gura_1388 hypothetical protein; PFAM: ABC-1; SPTR: 2-octaprenylphenol hydroxylase; IMG reference gene:2504785191; PFAM: ABC1 family. (561 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (269 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (152 aa)
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
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