STRINGSTRING
AEE14801.1 AEE14801.1 AEE15090.1 AEE15090.1 ribBA ribBA trpE trpE AEE15445.1 AEE15445.1 AEE15447.1 AEE15447.1 panD panD AEE14112.1 AEE14112.1 pckA pckA tal tal mqnD mqnD lysA lysA AEE14065.1 AEE14065.1 thiC thiC speH speH AEE14372.1 AEE14372.1 AEE14378.1 AEE14378.1 AEE14421.1 AEE14421.1 AEE14586.1 AEE14586.1 moaA moaA AEE14721.1 AEE14721.1 AEE14799.1 AEE14799.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEE14801.1Ketose-bisphosphate aldolase class-II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: sul:SYO3AOP1_0025 aldolase; PFAM: Ketose-bisphosphate aldolase, class-II; SPTR: Aldolase; IMG reference gene:2504784590; PFAM: Fructose-bisphosphate aldolase class-II. (471 aa)
AEE15090.1Menaquinone biosynthesis decarboxylase, SCO4490 family; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: hor:Hore_14820 UbiD family decarboxylase; PFAM: Carboxylyase-related; SPTR: UbiD family decarboxylase; TIGRFAM: menaquinone biosynthesis decarboxylase, SCO4490 family; Carboxylyase-related; IMG reference gene:2504784889; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: menaquinone biosynthesis decarboxylase, SCO4490 family; UbiD family decarboxylases; Belongs to the UbiD family. (483 aa)
ribBAGTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (401 aa)
trpEAnthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (481 aa)
AEE15445.1Glutamine amidotransferase of anthranilate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR006221:IPR000991; KEGG: aae:aq_549 anthranilate synthase component II; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase component II; TIGRFAM: Glutamine amidotransferase of anthranilate synthase; IMG reference gene:2504785256; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (196 aa)
AEE15447.1COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: ttm:Tthe_1228 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase; IMG reference gene:2504785258; PFAM: Indole-3-glycerol phosphate synthase. (264 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (115 aa)
AEE14112.1Protein of unknown function DUF100; COGs: COG1980 fructose 1 6-bisphosphatase; InterPro IPR002803; KEGG: tte:TTE0285 hypothetical protein; PFAM: Fructose-1,6-bisphosphatase, class V; SPTR: Putative uncharacterized protein; IMG reference gene:2504783851; PFAM: Fructose-1,6-bisphosphatase. (282 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (511 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
mqnDHypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (274 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (427 aa)
AEE14065.1Ribulose bisphosphate carboxylase, type III; COGs: COG1850 Ribulose 1 5-bisphosphate carboxylase large subunit; InterPro IPR017712:IPR017444:IPR000685; KEGG: adg:Adeg_1863 ribulose bisphosphate carboxylase, type III; PFAM: Ribulose bisphosphate carboxylase, large subunit, C-terminal; Ribulose bisphosphate carboxylase, large subunit, N-terminal; PRIAM: Ribulose-bisphosphate carboxylase; SPTR: Ribulose bisphosphate carboxylase, type III; TIGRFAM: Ribulose bisphosphate carboxylase, large subunit, type III; IMG reference gene:2504783801; PFAM: Ribulose bisphosphate carboxylase large chain, [...] (429 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (432 aa)
speHS-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (134 aa)
AEE14372.1COGs: COG1945 conserved hypothetical protein; HAMAP: Pyruvoyl-dependent arginine decarboxylase; InterPro IPR002724; KEGG: mif:Metin_1355 arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase; PRIAM: Arginine decarboxylase; SPTR: Pyruvoyl-dependent arginine decarboxylase; TIGRFAM: Pyruvoyl-dependent arginine decarboxylase; IMG reference gene:2504784124; PFAM: Pyruvoyl-dependent arginine decarboxylase (PvlArgDC); TIGRFAM: arginine decarboxylase, pyruvoyl-dependent. (154 aa)
AEE14378.1Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006268; KEGG: thx:Thet_1477 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: Phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; IMG reference gene:2504784130; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. (336 aa)
AEE14421.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (392 aa)
AEE14586.1Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). (232 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (324 aa)
AEE14721.1Carboxyvinyl-carboxyphosphonatephosphorylmutase; COGs: COG2513 PEP phosphonomutase; InterPro IPR000918; KEGG: nth:Nther_2154 carboxyvinyl-carboxyphosphonate phosphorylmutase; PFAM: Isocitrate lyase/phosphorylmutase; PRIAM: Carboxyvinyl-carboxyphosphonate phosphorylmutase; SPTR: Methylisocitrate lyase; IMG reference gene:2504784498; PFAM: Isocitrate lyase family; TIGRFAM: carboxyvinyl-carboxyphosphonate phosphorylmutase. (292 aa)
AEE14799.1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.