(6 nodes) Synthesis of diphthamide-EEF2 network (Heterobasidion irregulare)

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query proteins and first shell of interactors

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second shell of interactors

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Your Input:
	W4JPM2_9AGAM	TP_methylase domain-containing protein. (291 aa)
	W4JSY3_9AGAM	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily. (525 aa)
	W4JTL3_9AGAM	DPH-type MB domain-containing protein. (67 aa)
	W4K822_9AGAM	Uncharacterized protein. (394 aa)
	W4KDC0_9AGAM	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (463 aa)
	W4KDP0_9AGAM	Diphthami_syn_2 domain-containing protein. (679 aa)

Your Current Organism:

Heterobasidion irregulare

NCBI taxonomy Id: 747525
Other names: H. irregulare TC 32-1, Heterobasidion irregulare TC 32-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
W4JPM2_9AGAM	W4JSY3_9AGAM	W4JPM2	W4JSY3	TP_methylase domain-containing protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily.	0.832
W4JPM2_9AGAM	W4JTL3_9AGAM	W4JPM2	W4JTL3	TP_methylase domain-containing protein.	DPH-type MB domain-containing protein.	0.583
W4JPM2_9AGAM	W4K822_9AGAM	W4JPM2	W4K822	TP_methylase domain-containing protein.	Uncharacterized protein.	0.822
W4JPM2_9AGAM	W4KDC0_9AGAM	W4JPM2	W4KDC0	TP_methylase domain-containing protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.838
W4JPM2_9AGAM	W4KDP0_9AGAM	W4JPM2	W4KDP0	TP_methylase domain-containing protein.	Diphthami_syn_2 domain-containing protein.	0.881
W4JSY3_9AGAM	W4JPM2_9AGAM	W4JSY3	W4JPM2	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily.	TP_methylase domain-containing protein.	0.832
W4JSY3_9AGAM	W4JTL3_9AGAM	W4JSY3	W4JTL3	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily.	DPH-type MB domain-containing protein.	0.988
W4JSY3_9AGAM	W4K822_9AGAM	W4JSY3	W4K822	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily.	Uncharacterized protein.	0.731
W4JSY3_9AGAM	W4KDC0_9AGAM	W4JSY3	W4KDC0	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.998
W4JSY3_9AGAM	W4KDP0_9AGAM	W4JSY3	W4KDP0	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily.	Diphthami_syn_2 domain-containing protein.	0.613
W4JTL3_9AGAM	W4JPM2_9AGAM	W4JTL3	W4JPM2	DPH-type MB domain-containing protein.	TP_methylase domain-containing protein.	0.583
W4JTL3_9AGAM	W4JSY3_9AGAM	W4JTL3	W4JSY3	DPH-type MB domain-containing protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily.	0.988
W4JTL3_9AGAM	W4K822_9AGAM	W4JTL3	W4K822	DPH-type MB domain-containing protein.	Uncharacterized protein.	0.647
W4JTL3_9AGAM	W4KDC0_9AGAM	W4JTL3	W4KDC0	DPH-type MB domain-containing protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.987
W4JTL3_9AGAM	W4KDP0_9AGAM	W4JTL3	W4KDP0	DPH-type MB domain-containing protein.	Diphthami_syn_2 domain-containing protein.	0.613
W4K822_9AGAM	W4JPM2_9AGAM	W4K822	W4JPM2	Uncharacterized protein.	TP_methylase domain-containing protein.	0.822
W4K822_9AGAM	W4JSY3_9AGAM	W4K822	W4JSY3	Uncharacterized protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily.	0.731
W4K822_9AGAM	W4JTL3_9AGAM	W4K822	W4JTL3	Uncharacterized protein.	DPH-type MB domain-containing protein.	0.647
W4K822_9AGAM	W4KDC0_9AGAM	W4K822	W4KDC0	Uncharacterized protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.731
W4K822_9AGAM	W4KDP0_9AGAM	W4K822	W4KDP0	Uncharacterized protein.	Diphthami_syn_2 domain-containing protein.	0.980