STRINGSTRING
W4JNQ0_9AGAM W4JNQ0_9AGAM W4JP70_9AGAM W4JP70_9AGAM W4JQC1_9AGAM W4JQC1_9AGAM W4JQG4_9AGAM W4JQG4_9AGAM W4JQI2_9AGAM W4JQI2_9AGAM W4JQN6_9AGAM W4JQN6_9AGAM W4JQT9_9AGAM W4JQT9_9AGAM W4JR22_9AGAM W4JR22_9AGAM W4JR75_9AGAM W4JR75_9AGAM W4JRP8_9AGAM W4JRP8_9AGAM W4JRQ8_9AGAM W4JRQ8_9AGAM W4JS31_9AGAM W4JS31_9AGAM W4JS76_9AGAM W4JS76_9AGAM W4JSB8_9AGAM W4JSB8_9AGAM W4JTI8_9AGAM W4JTI8_9AGAM W4JTL8_9AGAM W4JTL8_9AGAM W4JTU0_9AGAM W4JTU0_9AGAM W4JUF2_9AGAM W4JUF2_9AGAM W4JUH8_9AGAM W4JUH8_9AGAM W4JUT8_9AGAM W4JUT8_9AGAM W4JUZ2_9AGAM W4JUZ2_9AGAM W4JV61_9AGAM W4JV61_9AGAM W4JVE7_9AGAM W4JVE7_9AGAM W4JVI3_9AGAM W4JVI3_9AGAM W4JVL7_9AGAM W4JVL7_9AGAM W4JWU7_9AGAM W4JWU7_9AGAM W4JXN3_9AGAM W4JXN3_9AGAM W4JY11_9AGAM W4JY11_9AGAM W4JY21_9AGAM W4JY21_9AGAM W4JY75_9AGAM W4JY75_9AGAM W4JYK3_9AGAM W4JYK3_9AGAM W4JYV2_9AGAM W4JYV2_9AGAM W4JZ69_9AGAM W4JZ69_9AGAM W4JZN5_9AGAM W4JZN5_9AGAM W4JZT1_9AGAM W4JZT1_9AGAM W4JZV2_9AGAM W4JZV2_9AGAM ubc1 ubc1 W4K0D9_9AGAM W4K0D9_9AGAM W4K0E2_9AGAM W4K0E2_9AGAM W4K193_9AGAM W4K193_9AGAM W4K1F3_9AGAM W4K1F3_9AGAM W4K1V4_9AGAM W4K1V4_9AGAM W4K1W0_9AGAM W4K1W0_9AGAM W4K1X8_9AGAM W4K1X8_9AGAM W4K252_9AGAM W4K252_9AGAM W4K2W0_9AGAM W4K2W0_9AGAM W4K2X3_9AGAM W4K2X3_9AGAM W4K396_9AGAM W4K396_9AGAM W4K3A0_9AGAM W4K3A0_9AGAM W4K3N4_9AGAM W4K3N4_9AGAM W4K3Q1_9AGAM W4K3Q1_9AGAM W4K3T3_9AGAM W4K3T3_9AGAM W4K3W5_9AGAM W4K3W5_9AGAM W4K3Z6_9AGAM W4K3Z6_9AGAM W4K424_9AGAM W4K424_9AGAM W4K4D6_9AGAM W4K4D6_9AGAM W4K4L9_9AGAM W4K4L9_9AGAM W4K4P8_9AGAM W4K4P8_9AGAM W4K543_9AGAM W4K543_9AGAM W4K5B2_9AGAM W4K5B2_9AGAM W4K5D0_9AGAM W4K5D0_9AGAM W4K5D6_9AGAM W4K5D6_9AGAM W4K5Z8_9AGAM W4K5Z8_9AGAM W4K653_9AGAM W4K653_9AGAM TRX9 TRX9 W4K728_9AGAM W4K728_9AGAM W4K736_9AGAM W4K736_9AGAM W4K7D8_9AGAM W4K7D8_9AGAM W4K7I9_9AGAM W4K7I9_9AGAM W4K7L5_9AGAM W4K7L5_9AGAM W4K7Q8_9AGAM W4K7Q8_9AGAM W4K7S1_9AGAM W4K7S1_9AGAM W4K7T9_9AGAM W4K7T9_9AGAM W4K8V4_9AGAM W4K8V4_9AGAM W4K944_9AGAM W4K944_9AGAM W4K9A3_9AGAM W4K9A3_9AGAM W4K9D0_9AGAM W4K9D0_9AGAM W4KAA8_9AGAM W4KAA8_9AGAM W4KAD4_9AGAM W4KAD4_9AGAM W4KB23_9AGAM W4KB23_9AGAM W4KB99_9AGAM W4KB99_9AGAM W4KBE4_9AGAM W4KBE4_9AGAM W4KDJ9_9AGAM W4KDJ9_9AGAM W4KDL0_9AGAM W4KDL0_9AGAM W4KDL1_9AGAM W4KDL1_9AGAM W4KE05_9AGAM W4KE05_9AGAM W4KEG1_9AGAM W4KEG1_9AGAM W4KES7_9AGAM W4KES7_9AGAM W4KEU4_9AGAM W4KEU4_9AGAM W4KEW6_9AGAM W4KEW6_9AGAM W4KF06_9AGAM W4KF06_9AGAM W4KF62_9AGAM W4KF62_9AGAM W4KFA4_9AGAM W4KFA4_9AGAM W4KFF3_9AGAM W4KFF3_9AGAM W4KFM7_9AGAM W4KFM7_9AGAM W4KFN1_9AGAM W4KFN1_9AGAM W4KFS0_9AGAM W4KFS0_9AGAM W4KFS5_9AGAM W4KFS5_9AGAM W4KFX7_9AGAM W4KFX7_9AGAM W4KGX4_9AGAM W4KGX4_9AGAM W4KH32_9AGAM W4KH32_9AGAM W4KHG4_9AGAM W4KHG4_9AGAM W4KHQ0_9AGAM W4KHQ0_9AGAM W4KHS9_9AGAM W4KHS9_9AGAM W4KHY6_9AGAM W4KHY6_9AGAM W4KIB4_9AGAM W4KIB4_9AGAM W4KID1_9AGAM W4KID1_9AGAM W4KIE5_9AGAM W4KIE5_9AGAM W4KJ03_9AGAM W4KJ03_9AGAM W4KJ47_9AGAM W4KJ47_9AGAM W4KJD4_9AGAM W4KJD4_9AGAM W4KJE6_9AGAM W4KJE6_9AGAM W4KJH2_9AGAM W4KJH2_9AGAM W4KJI8_9AGAM W4KJI8_9AGAM W4KJM3_9AGAM W4KJM3_9AGAM W4KJN1_9AGAM W4KJN1_9AGAM W4KJR2_9AGAM W4KJR2_9AGAM W4KJV4_9AGAM W4KJV4_9AGAM W4KJZ9_9AGAM W4KJZ9_9AGAM W4KK49_9AGAM W4KK49_9AGAM W4KKH6_9AGAM W4KKH6_9AGAM W4KKM7_9AGAM W4KKM7_9AGAM W4KKP8_9AGAM W4KKP8_9AGAM W4KKT4_9AGAM W4KKT4_9AGAM W4KKU2_9AGAM W4KKU2_9AGAM W4KKX6_9AGAM W4KKX6_9AGAM W4KLE1_9AGAM W4KLE1_9AGAM W4KLI6_9AGAM W4KLI6_9AGAM W4KLM5_9AGAM W4KLM5_9AGAM W4KLT3_9AGAM W4KLT3_9AGAM W4KLY1_9AGAM W4KLY1_9AGAM W4KLY2_9AGAM W4KLY2_9AGAM W4KM48_9AGAM W4KM48_9AGAM W4KM50_9AGAM W4KM50_9AGAM W4KM86_9AGAM W4KM86_9AGAM W4KMB4_9AGAM W4KMB4_9AGAM W4KMQ7_9AGAM W4KMQ7_9AGAM W4KMQ9_9AGAM W4KMQ9_9AGAM W4KMV4_9AGAM W4KMV4_9AGAM W4KMW3_9AGAM W4KMW3_9AGAM W4KN17_9AGAM W4KN17_9AGAM ubc3 ubc3 W4KNV1_9AGAM W4KNV1_9AGAM W4KNW8_9AGAM W4KNW8_9AGAM W4KNY8_9AGAM W4KNY8_9AGAM W4KP28_9AGAM W4KP28_9AGAM W4KP72_9AGAM W4KP72_9AGAM W4KPA2_9AGAM W4KPA2_9AGAM W4KPB2_9AGAM W4KPB2_9AGAM W4KPI7_9AGAM W4KPI7_9AGAM W4KPL1_9AGAM W4KPL1_9AGAM ubc2 ubc2 W4KPR7_9AGAM W4KPR7_9AGAM W4KPT7_9AGAM W4KPT7_9AGAM W4KPU6_9AGAM W4KPU6_9AGAM W4KPW5_9AGAM W4KPW5_9AGAM W4KQ66_9AGAM W4KQ66_9AGAM W4KQ83_9AGAM W4KQ83_9AGAM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W4JNQ0_9AGAMProteasome subunit beta. (208 aa)
W4JP70_9AGAMUncharacterized protein. (676 aa)
W4JQC1_9AGAMNEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (521 aa)
W4JQG4_9AGAMSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (93 aa)
W4JQI2_9AGAMPKS_PP domain-containing protein. (972 aa)
W4JQN6_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein. (146 aa)
W4JQT9_9AGAM26S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (946 aa)
W4JR22_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
W4JR75_9AGAMMetallo peptidase M67A. (360 aa)
W4JRP8_9AGAMRING-type domain-containing protein. (1770 aa)
W4JRQ8_9AGAMPutative 26S proteasome regulatory complex, ATPase RPT6; Belongs to the AAA ATPase family. (401 aa)
W4JS31_9AGAMWD_REPEATS_REGION domain-containing protein. (1225 aa)
W4JS76_9AGAMProteasome subunit beta; Belongs to the peptidase T1B family. (263 aa)
W4JSB8_9AGAMThreonine protease T1. (274 aa)
W4JTI8_9AGAME3 ubiquitin-protein ligase. (770 aa)
W4JTL8_9AGAMUncharacterized protein. (429 aa)
W4JTU0_9AGAMUncharacterized protein. (405 aa)
W4JUF2_9AGAMUSP domain-containing protein. (673 aa)
W4JUH8_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (157 aa)
W4JUT8_9AGAMRING-type domain-containing protein. (108 aa)
W4JUZ2_9AGAMRad60-SLD domain-containing protein. (100 aa)
W4JV61_9AGAMUbiquitin-like domain-containing protein. (102 aa)
W4JVE7_9AGAMF-box domain-containing protein. (453 aa)
W4JVI3_9AGAMPCI domain-containing protein. (508 aa)
W4JVL7_9AGAMDSPc domain-containing protein. (166 aa)
W4JWU7_9AGAMUbiquitin-like domain-containing protein. (282 aa)
W4JXN3_9AGAMUncharacterized protein. (214 aa)
W4JY11_9AGAMUbiquitin carboxyl-terminal hydrolase. (820 aa)
W4JY21_9AGAMUncharacterized protein. (149 aa)
W4JY75_9AGAMCULLIN_2 domain-containing protein; Belongs to the cullin family. (810 aa)
W4JYK3_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
W4JYV2_9AGAMHelicase ATP-binding domain-containing protein. (2015 aa)
W4JZ69_9AGAMUbiquitin carboxyl-terminal hydrolase. (242 aa)
W4JZN5_9AGAMUncharacterized protein. (996 aa)
W4JZT1_9AGAMDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1527 aa)
W4JZV2_9AGAMHECT domain-containing protein. (2537 aa)
ubc1Ubiquitin-conjugating enzyme1. (129 aa)
W4K0D9_9AGAMUncharacterized protein. (689 aa)
W4K0E2_9AGAMPutative 26S proteasome regulatory complex, ATPase RPT4; Belongs to the AAA ATPase family. (399 aa)
W4K193_9AGAMUncharacterized protein; Belongs to the peptidase C19 family. (1277 aa)
W4K1F3_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein. (174 aa)
W4K1V4_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (178 aa)
W4K1W0_9AGAMUbiquitin carboxyl-terminal hydrolase. (537 aa)
W4K1X8_9AGAMUncharacterized protein. (823 aa)
W4K252_9AGAMTPR_REGION domain-containing protein. (1054 aa)
W4K2W0_9AGAMUncharacterized protein. (589 aa)
W4K2X3_9AGAMUbiquitin-like domain-containing protein. (423 aa)
W4K396_9AGAMUncharacterized protein. (276 aa)
W4K3A0_9AGAMUbiquitin carboxyl-terminal hydrolase. (323 aa)
W4K3N4_9AGAMUncharacterized protein. (394 aa)
W4K3Q1_9AGAMPCI domain-containing protein. (387 aa)
W4K3T3_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (173 aa)
W4K3W5_9AGAMOTU domain-containing protein. (266 aa)
W4K3Z6_9AGAMUncharacterized protein. (466 aa)
W4K424_9AGAME3 ubiquitin protein ligase. (545 aa)
W4K4D6_9AGAMF-box domain-containing protein. (568 aa)
W4K4L9_9AGAMDNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (788 aa)
W4K4P8_9AGAMDefective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (286 aa)
W4K543_9AGAMUncharacterized protein. (158 aa)
W4K5B2_9AGAMProteasome subunit alpha type. (261 aa)
W4K5D0_9AGAMUncharacterized protein. (300 aa)
W4K5D6_9AGAMPCI domain-containing protein. (503 aa)
W4K5Z8_9AGAMRBR-type E3 ubiquitin transferase. (543 aa)
W4K653_9AGAMHECT domain-containing protein. (955 aa)
TRX9TRX family. (634 aa)
W4K728_9AGAMProteasome assembly chaperone 2; Involved in 20S proteasome assembly. Belongs to the PSMG2 family. (259 aa)
W4K736_9AGAMUncharacterized protein. (302 aa)
W4K7D8_9AGAMUncharacterized protein. (208 aa)
W4K7I9_9AGAMRPN13_C domain-containing protein. (307 aa)
W4K7L5_9AGAMCULLIN_2 domain-containing protein; Belongs to the cullin family. (763 aa)
W4K7Q8_9AGAMThiF domain-containing protein. (341 aa)
W4K7S1_9AGAMCPSF_A domain-containing protein. (1254 aa)
W4K7T9_9AGAMWD_REPEATS_REGION domain-containing protein. (811 aa)
W4K8V4_9AGAMCysteine peptidase C48. (658 aa)
W4K944_9AGAMUncharacterized protein. (363 aa)
W4K9A3_9AGAMUncharacterized protein. (948 aa)
W4K9D0_9AGAM26S proteasome regulatory complex, ATPase RPT5; Belongs to the AAA ATPase family. (459 aa)
W4KAA8_9AGAMANK_REP_REGION domain-containing protein. (218 aa)
W4KAD4_9AGAMProteasome subunit beta. (253 aa)
W4KB23_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (221 aa)
W4KB99_9AGAMCULLIN_2 domain-containing protein; Belongs to the cullin family. (733 aa)
W4KBE4_9AGAM26S proteasome regulatory complex, ATPase RPT2; Belongs to the AAA ATPase family. (449 aa)
W4KDJ9_9AGAMMetallo peptidase M67A. (310 aa)
W4KDL0_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
W4KDL1_9AGAMF-box domain-containing protein. (557 aa)
W4KE05_9AGAMUncharacterized protein. (504 aa)
W4KEG1_9AGAMUbiquitin-like domain-containing protein. (78 aa)
W4KES7_9AGAMProteasome subunit beta. (194 aa)
W4KEU4_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein. (884 aa)
W4KEW6_9AGAMProteasome subunit alpha type. (255 aa)
W4KF06_9AGAMWD_REPEATS_REGION domain-containing protein. (466 aa)
W4KF62_9AGAMProteasome subunit alpha type. (278 aa)
W4KFA4_9AGAMUncharacterized protein. (229 aa)
W4KFF3_9AGAMProteasome subunit beta. (233 aa)
W4KFM7_9AGAMUBA_e1_C domain-containing protein. (1010 aa)
W4KFN1_9AGAMVWFA domain-containing protein. (259 aa)
W4KFS0_9AGAMPCI domain-containing protein. (265 aa)
W4KFS5_9AGAMUncharacterized protein. (340 aa)
W4KFX7_9AGAMPCI domain-containing protein. (453 aa)
W4KGX4_9AGAMProteasome subunit alpha type. (247 aa)
W4KH32_9AGAMUncharacterized protein. (553 aa)
W4KHG4_9AGAMUbiquitin-like domain-containing protein. (797 aa)
W4KHQ0_9AGAMProteasome subunit alpha type. (263 aa)
W4KHS9_9AGAMDefective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (220 aa)
W4KHY6_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein. (417 aa)
W4KIB4_9AGAMUncharacterized protein. (119 aa)
W4KID1_9AGAMUncharacterized protein. (1631 aa)
W4KIE5_9AGAMAAA ATPase; Belongs to the AAA ATPase family. (453 aa)
W4KJ03_9AGAMUncharacterized protein. (496 aa)
W4KJ47_9AGAMDNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (454 aa)
W4KJD4_9AGAMCysteine protease; Belongs to the peptidase C19 family. (1104 aa)
W4KJE6_9AGAMProteasome subunit beta. (313 aa)
W4KJH2_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
W4KJI8_9AGAMUncharacterized protein. (344 aa)
W4KJM3_9AGAMUncharacterized protein. (291 aa)
W4KJN1_9AGAMUncharacterized protein. (942 aa)
W4KJR2_9AGAMWD_REPEATS_REGION domain-containing protein. (582 aa)
W4KJV4_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
W4KJZ9_9AGAMOTU domain-containing protein. (293 aa)
W4KK49_9AGAMProteasome subunit alpha type. (260 aa)
W4KKH6_9AGAMUncharacterized protein. (889 aa)
W4KKM7_9AGAMUncharacterized protein. (650 aa)
W4KKP8_9AGAMUncharacterized protein. (355 aa)
W4KKT4_9AGAMProteasome subunit alpha type. (241 aa)
W4KKU2_9AGAMUncharacterized protein; Belongs to the SKP1 family. (160 aa)
W4KKX6_9AGAM26S proteasome regulatory complex, ATPase RPT3; Belongs to the AAA ATPase family. (413 aa)
W4KLE1_9AGAMUncharacterized protein. (337 aa)
W4KLI6_9AGAMUSP domain-containing protein. (1430 aa)
W4KLM5_9AGAMUncharacterized protein. (266 aa)
W4KLT3_9AGAMUncharacterized protein. (1591 aa)
W4KLY1_9AGAME2_bind domain-containing protein. (434 aa)
W4KLY2_9AGAMPCI domain-containing protein. (428 aa)
W4KM48_9AGAMUncharacterized protein. (685 aa)
W4KM50_9AGAMUncharacterized protein. (308 aa)
W4KM86_9AGAMCSN8_PSD8_EIF3K domain-containing protein. (172 aa)
W4KMB4_9AGAMCysteine peptidase C19. (201 aa)
W4KMQ7_9AGAMPCI domain-containing protein. (474 aa)
W4KMQ9_9AGAMMPN domain-containing protein. (338 aa)
W4KMV4_9AGAMUncharacterized protein. (494 aa)
W4KMW3_9AGAMPCI domain-containing protein. (385 aa)
W4KN17_9AGAMUncharacterized protein. (755 aa)
ubc3Ubiquitin-conjugating enzyme3 like-protein. (944 aa)
W4KNV1_9AGAMWD_REPEATS_REGION domain-containing protein. (496 aa)
W4KNW8_9AGAMUbiquitin-like domain-containing protein. (128 aa)
W4KNY8_9AGAMUncharacterized protein. (562 aa)
W4KP28_9AGAMMPN domain-containing protein. (322 aa)
W4KP72_9AGAMPCI domain-containing protein. (469 aa)
W4KPA2_9AGAMUncharacterized protein. (140 aa)
W4KPB2_9AGAMUncharacterized protein. (306 aa)
W4KPI7_9AGAME3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1814 aa)
W4KPL1_9AGAMUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (178 aa)
ubc2Ubiquitin-conjugating enzyme2. (153 aa)
W4KPR7_9AGAM26S proteasome regulatory subunit RPN2; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (1010 aa)
W4KPT7_9AGAMPCI domain-containing protein. (173 aa)
W4KPU6_9AGAMUncharacterized protein. (257 aa)
W4KPW5_9AGAMTIP120 domain-containing protein. (1219 aa)
W4KQ66_9AGAMUncharacterized protein. (2016 aa)
W4KQ83_9AGAMUncharacterized protein. (1933 aa)
Your Current Organism:
Heterobasidion irregulare
NCBI taxonomy Id: 747525
Other names: H. irregulare TC 32-1, Heterobasidion irregulare TC 32-1
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