10 items (Heterobasidion irregulare) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W4JP70_9AGAM	Uncharacterized protein. (676 aa)
	W4JUZ2_9AGAM	Rad60-SLD domain-containing protein. (100 aa)
	W4JV61_9AGAM	Ubiquitin-like domain-containing protein. (102 aa)
	W4JZT1_9AGAM	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1527 aa)
	W4K4L9_9AGAM	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (788 aa)
	W4K7Q8_9AGAM	ThiF domain-containing protein. (341 aa)
	W4K8V4_9AGAM	Cysteine peptidase C48. (658 aa)
	W4KJV4_9AGAM	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	W4KM48_9AGAM	Uncharacterized protein. (685 aa)
	W4KMV4_9AGAM	Uncharacterized protein. (494 aa)

Your Current Organism:

Heterobasidion irregulare

NCBI taxonomy Id: 747525
Other names: H. irregulare TC 32-1, Heterobasidion irregulare TC 32-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
W4JP70_9AGAM	W4JUZ2_9AGAM	W4JP70	W4JUZ2	Uncharacterized protein.	Rad60-SLD domain-containing protein.	0.932
W4JP70_9AGAM	W4JV61_9AGAM	W4JP70	W4JV61	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.932
W4JP70_9AGAM	W4K7Q8_9AGAM	W4JP70	W4K7Q8	Uncharacterized protein.	ThiF domain-containing protein.	0.999
W4JP70_9AGAM	W4K8V4_9AGAM	W4JP70	W4K8V4	Uncharacterized protein.	Cysteine peptidase C48.	0.662
W4JP70_9AGAM	W4KJV4_9AGAM	W4JP70	W4KJV4	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.998
W4JP70_9AGAM	W4KM48_9AGAM	W4JP70	W4KM48	Uncharacterized protein.	Uncharacterized protein.	0.611
W4JP70_9AGAM	W4KMV4_9AGAM	W4JP70	W4KMV4	Uncharacterized protein.	Uncharacterized protein.	0.905
W4JUZ2_9AGAM	W4JP70_9AGAM	W4JUZ2	W4JP70	Rad60-SLD domain-containing protein.	Uncharacterized protein.	0.932
W4JUZ2_9AGAM	W4JV61_9AGAM	W4JUZ2	W4JV61	Rad60-SLD domain-containing protein.	Ubiquitin-like domain-containing protein.	0.900
W4JUZ2_9AGAM	W4JZT1_9AGAM	W4JUZ2	W4JZT1	Rad60-SLD domain-containing protein.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.747
W4JUZ2_9AGAM	W4K4L9_9AGAM	W4JUZ2	W4K4L9	Rad60-SLD domain-containing protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.691
W4JUZ2_9AGAM	W4K7Q8_9AGAM	W4JUZ2	W4K7Q8	Rad60-SLD domain-containing protein.	ThiF domain-containing protein.	0.938
W4JUZ2_9AGAM	W4K8V4_9AGAM	W4JUZ2	W4K8V4	Rad60-SLD domain-containing protein.	Cysteine peptidase C48.	0.925
W4JUZ2_9AGAM	W4KJV4_9AGAM	W4JUZ2	W4KJV4	Rad60-SLD domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.995
W4JUZ2_9AGAM	W4KM48_9AGAM	W4JUZ2	W4KM48	Rad60-SLD domain-containing protein.	Uncharacterized protein.	0.935
W4JV61_9AGAM	W4JP70_9AGAM	W4JV61	W4JP70	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.932
W4JV61_9AGAM	W4JUZ2_9AGAM	W4JV61	W4JUZ2	Ubiquitin-like domain-containing protein.	Rad60-SLD domain-containing protein.	0.900
W4JV61_9AGAM	W4JZT1_9AGAM	W4JV61	W4JZT1	Ubiquitin-like domain-containing protein.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.747
W4JV61_9AGAM	W4K4L9_9AGAM	W4JV61	W4K4L9	Ubiquitin-like domain-containing protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.691
W4JV61_9AGAM	W4K7Q8_9AGAM	W4JV61	W4K7Q8	Ubiquitin-like domain-containing protein.	ThiF domain-containing protein.	0.938