35 items (Heterobasidion irregulare) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W4JSL0_9AGAM	CP-type G domain-containing protein. (400 aa)
	W4KNR3_9AGAM	NTF2 domain-containing protein. (155 aa)
	W4KNF9_9AGAM	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (665 aa)
	W4KNF7_9AGAM	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (670 aa)
	W4KM87_9AGAM	Sec3-PIP2_bind domain-containing protein. (1132 aa)
	W4KM45_9AGAM	CP-type G domain-containing protein. (684 aa)
	W4KLX1_9AGAM	Uncharacterized protein. (534 aa)
	W4KLW0_9AGAM	Uncharacterized protein. (287 aa)
	W4KJL9_9AGAM	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (212 aa)
	W4KIG3_9AGAM	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (750 aa)
	W4KHL9_9AGAM	Uncharacterized protein. (846 aa)
	W4KG86_9AGAM	Uncharacterized protein. (1408 aa)
	W4KFE6_9AGAM	Uncharacterized protein. (571 aa)
	W4KEK2_9AGAM	Uncharacterized protein. (665 aa)
	W4KEE4_9AGAM	Protein kinase domain-containing protein. (372 aa)
	W4KDI0_9AGAM	Uncharacterized protein. (361 aa)
	W4KD85_9AGAM	Putative ABC transporter. (637 aa)
	W4KD04_9AGAM	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (309 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (245 aa)
	W4KBA0_9AGAM	AAA ATPase. (763 aa)
	W4KB38_9AGAM	Uncharacterized protein. (555 aa)
	W4KAZ5_9AGAM	Uncharacterized protein. (590 aa)
	W4KAI9_9AGAM	WD_REPEATS_REGION domain-containing protein. (353 aa)
	W4KA92_9AGAM	Nuclear AAA ATPase. (259 aa)
	W4K7W5_9AGAM	SGF29 C-terminal domain-containing protein. (327 aa)
	W4K5Q5_9AGAM	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (666 aa)
	W4K222_9AGAM	C2H2-type domain-containing protein. (129 aa)
	cep2	Cep2 cellulose medium expressed protein 2. (85 aa)
	W4K153_9AGAM	Uncharacterized protein. (79 aa)
	W4K0A2_9AGAM	Uncharacterized protein. (750 aa)
	W4JXD5_9AGAM	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (453 aa)
	W4JWW1_9AGAM	ABC transporter. (305 aa)
	W4JW64_9AGAM	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (569 aa)
	W4JW49_9AGAM	Serine/threonine-protein kinase. (826 aa)
	W4JUH3_9AGAM	J domain-containing protein. (320 aa)

Your Current Organism:

Heterobasidion irregulare

NCBI taxonomy Id: 747525
Other names: H. irregulare TC 32-1, Heterobasidion irregulare TC 32-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TIF6	W4JSL0_9AGAM	W4KC40	W4JSL0	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	CP-type G domain-containing protein.	0.879
TIF6	W4JW64_9AGAM	W4KC40	W4JW64	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.	0.985
TIF6	W4JWW1_9AGAM	W4KC40	W4JWW1	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	ABC transporter.	0.656
TIF6	W4JXD5_9AGAM	W4KC40	W4JXD5	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.	0.647
TIF6	W4K222_9AGAM	W4KC40	W4K222	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	C2H2-type domain-containing protein.	0.982
TIF6	W4K5Q5_9AGAM	W4KC40	W4K5Q5	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.996
TIF6	W4KB38_9AGAM	W4KC40	W4KB38	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Uncharacterized protein.	0.505
TIF6	W4KD04_9AGAM	W4KC40	W4KD04	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.499
TIF6	W4KD85_9AGAM	W4KC40	W4KD85	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Putative ABC transporter.	0.637
TIF6	W4KEK2_9AGAM	W4KC40	W4KEK2	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Uncharacterized protein.	0.879
TIF6	W4KIG3_9AGAM	W4KC40	W4KIG3	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.	0.850
TIF6	W4KM45_9AGAM	W4KC40	W4KM45	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	CP-type G domain-containing protein.	0.981
TIF6	W4KNF7_9AGAM	W4KC40	W4KNF7	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	0.770
TIF6	W4KNF9_9AGAM	W4KC40	W4KNF9	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.983
W4JSL0_9AGAM	TIF6	W4JSL0	W4KC40	CP-type G domain-containing protein.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	0.879
W4JSL0_9AGAM	W4JW64_9AGAM	W4JSL0	W4JW64	CP-type G domain-containing protein.	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.	0.871
W4JSL0_9AGAM	W4JWW1_9AGAM	W4JSL0	W4JWW1	CP-type G domain-containing protein.	ABC transporter.	0.426
W4JSL0_9AGAM	W4JXD5_9AGAM	W4JSL0	W4JXD5	CP-type G domain-containing protein.	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.	0.827
W4JSL0_9AGAM	W4K222_9AGAM	W4JSL0	W4K222	CP-type G domain-containing protein.	C2H2-type domain-containing protein.	0.892
W4JSL0_9AGAM	W4K5Q5_9AGAM	W4JSL0	W4K5Q5	CP-type G domain-containing protein.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.976