76 items (Heterobasidion irregulare) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W4KLI4_9AGAM	Uncharacterized protein. (765 aa)
	W4JNG0_9AGAM	TPR_MLP1_2 domain-containing protein. (307 aa)
	W4JNF4_9AGAM	Uncharacterized protein. (127 aa)
	W4JN17_9AGAM	Uncharacterized protein. (276 aa)
	W4KK05_9AGAM	Uncharacterized protein. (547 aa)
	W4KJL9_9AGAM	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (212 aa)
	W4KHL9_9AGAM	Uncharacterized protein. (846 aa)
	W4KGI1_9AGAM	Uncharacterized protein. (874 aa)
	W4KG96_9AGAM	PCI domain-containing protein. (398 aa)
	W4KF53_9AGAM	Uncharacterized protein. (206 aa)
	W4KF45_9AGAM	Uncharacterized protein. (2256 aa)
	W4KES5_9AGAM	Uncharacterized protein. (345 aa)
	W4KEM9_9AGAM	Nucleoporin, serine protease S59. (131 aa)
	W4KEK2_9AGAM	Uncharacterized protein. (665 aa)
	W4KDK1_9AGAM	TFIIS N-terminal domain-containing protein. (915 aa)
	W4KDB4_9AGAM	Uncharacterized protein; Belongs to the DEAD box helicase family. (482 aa)
	W4KDB3_9AGAM	RanBD1 domain-containing protein. (207 aa)
	W4KD85_9AGAM	Putative ABC transporter. (637 aa)
	W4KD71_9AGAM	Uncharacterized protein. (1986 aa)
	W4KD19_9AGAM	Uncharacterized protein. (366 aa)
	W4KD04_9AGAM	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (309 aa)
	W4KCQ4_9AGAM	Uncharacterized protein. (1099 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (245 aa)
	W4KBU5_9AGAM	Uncharacterized protein. (101 aa)
	W4KIG3_9AGAM	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (750 aa)
	cep2	Cep2 cellulose medium expressed protein 2. (85 aa)
	W4K219_9AGAM	TPR_MLP1_2 domain-containing protein. (145 aa)
	W4K222_9AGAM	C2H2-type domain-containing protein. (129 aa)
	W4K2L2_9AGAM	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (714 aa)
	W4K2V6_9AGAM	Uncharacterized protein. (119 aa)
	W4K3M5_9AGAM	Protein kinase domain-containing protein. (710 aa)
	W4K3P2_9AGAM	ABC transporter. (1077 aa)
	W4K4D4_9AGAM	Importin N-terminal domain-containing protein. (977 aa)
	W4K5Q5_9AGAM	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (666 aa)
	W4K804_9AGAM	FHA domain-containing protein. (313 aa)
	W4K8E3_9AGAM	TPR_MLP1_2 domain-containing protein. (1856 aa)
	W4K9M4_9AGAM	Uncharacterized protein. (886 aa)
	W4K9P9_9AGAM	Uncharacterized protein. (146 aa)
	W4KA92_9AGAM	Nuclear AAA ATPase. (259 aa)
	W4KAI9_9AGAM	WD_REPEATS_REGION domain-containing protein. (353 aa)
	W4KAZ5_9AGAM	Uncharacterized protein. (590 aa)
	W4KB38_9AGAM	Uncharacterized protein. (555 aa)
	W4KB57_9AGAM	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (1070 aa)
	W4KBA0_9AGAM	AAA ATPase. (763 aa)
	W4KBA3_9AGAM	Uncharacterized protein. (582 aa)
	W4K1H3_9AGAM	RPOL4c domain-containing protein. (134 aa)
	W4JZ59_9AGAM	Nuclear pore protein. (864 aa)
	W4JY87_9AGAM	Uncharacterized protein. (550 aa)
	W4JY71_9AGAM	Uncharacterized protein. (119 aa)
	W4JY35_9AGAM	TPR_MLP1_2 domain-containing protein. (145 aa)
	W4JY24_9AGAM	Uncharacterized protein. (160 aa)
	W4JXS3_9AGAM	Uncharacterized protein. (192 aa)
	W4JXD5_9AGAM	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (453 aa)
	W4JXA2_9AGAM	RRM domain-containing protein. (226 aa)
	W4JWW1_9AGAM	ABC transporter. (305 aa)
	W4JWV6_9AGAM	Nup96 domain-containing protein. (893 aa)
	W4JWQ2_9AGAM	RRM domain-containing protein. (93 aa)
	W4JW64_9AGAM	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (569 aa)
	W4JW14_9AGAM	Uncharacterized protein. (177 aa)
	W4JV79_9AGAM	Uncharacterized protein. (112 aa)
	W4JUH3_9AGAM	J domain-containing protein. (320 aa)
	W4JTW8_9AGAM	Uncharacterized protein. (1465 aa)
	W4JTI3_9AGAM	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (797 aa)
	W4JSL0_9AGAM	CP-type G domain-containing protein. (400 aa)
	SUS1	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...] (99 aa)
	W4JQN5_9AGAM	Uncharacterized protein. (488 aa)
	nrap1	U3 small nucleolar RNA-associated protein 22. (1272 aa)
	W4JNY1_9AGAM	Uncharacterized protein. (920 aa)
	W4KPX8_9AGAM	Uncharacterized protein. (1370 aa)
	W4KPP8_9AGAM	Uncharacterized protein. (438 aa)
	W4KNR3_9AGAM	NTF2 domain-containing protein. (155 aa)
	W4KNF9_9AGAM	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (665 aa)
	W4KNF7_9AGAM	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (670 aa)
	W4KM45_9AGAM	CP-type G domain-containing protein. (684 aa)
	W4KLX1_9AGAM	Uncharacterized protein. (534 aa)
	W4KLW0_9AGAM	Uncharacterized protein. (287 aa)

Your Current Organism:

Heterobasidion irregulare

NCBI taxonomy Id: 747525
Other names: H. irregulare TC 32-1, Heterobasidion irregulare TC 32-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SUS1	W4JTW8_9AGAM	W4JSE2	W4JTW8	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	Uncharacterized protein.	0.996
SUS1	W4JXA2_9AGAM	W4JSE2	W4JXA2	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	RRM domain-containing protein.	0.525
SUS1	W4KAI9_9AGAM	W4JSE2	W4KAI9	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	WD_REPEATS_REGION domain-containing protein.	0.519
SUS1	W4KAZ5_9AGAM	W4JSE2	W4KAZ5	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	Uncharacterized protein.	0.714
SUS1	W4KBU5_9AGAM	W4JSE2	W4KBU5	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	Uncharacterized protein.	0.706
SUS1	W4KES5_9AGAM	W4JSE2	W4KES5	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	Uncharacterized protein.	0.754
SUS1	W4KG96_9AGAM	W4JSE2	W4KG96	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	PCI domain-containing protein.	0.877
SUS1	W4KLI4_9AGAM	W4JSE2	W4KLI4	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	Uncharacterized protein.	0.435
SUS1	W4KPP8_9AGAM	W4JSE2	W4KPP8	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	Uncharacterized protein.	0.626
TIF6	W4JSL0_9AGAM	W4KC40	W4JSL0	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	CP-type G domain-containing protein.	0.879
TIF6	W4JW64_9AGAM	W4KC40	W4JW64	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.	0.985
TIF6	W4JWW1_9AGAM	W4KC40	W4JWW1	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	ABC transporter.	0.656
TIF6	W4JXD5_9AGAM	W4KC40	W4JXD5	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.	0.647
TIF6	W4K222_9AGAM	W4KC40	W4K222	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	C2H2-type domain-containing protein.	0.982
TIF6	W4K5Q5_9AGAM	W4KC40	W4K5Q5	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.996
TIF6	W4KB38_9AGAM	W4KC40	W4KB38	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Uncharacterized protein.	0.505
TIF6	W4KD04_9AGAM	W4KC40	W4KD04	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.499
TIF6	W4KD85_9AGAM	W4KC40	W4KD85	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Putative ABC transporter.	0.637
TIF6	W4KEK2_9AGAM	W4KC40	W4KEK2	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Uncharacterized protein.	0.879
TIF6	W4KIG3_9AGAM	W4KC40	W4KIG3	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.	0.850