55 items (Heterobasidion irregulare) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	W4KKG5_9AGAM	Uncharacterized protein. (282 aa)
	W4KKX6_9AGAM	26S proteasome regulatory complex, ATPase RPT3; Belongs to the AAA ATPase family. (413 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
	W4KLF0_9AGAM	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (617 aa)
	W4KLG3_9AGAM	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1566 aa)
	W4KLP0_9AGAM	Uncharacterized protein. (343 aa)
	W4KM57_9AGAM	Uncharacterized protein. (163 aa)
	W4KMS5_9AGAM	Uncharacterized protein. (483 aa)
	W4KMT5_9AGAM	Uncharacterized protein. (1163 aa)
	W4KMZ6_9AGAM	DNA ligase. (830 aa)
	W4KN22_9AGAM	Uncharacterized protein. (1477 aa)
	W4KN86_9AGAM	Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. (153 aa)
	W4KND0_9AGAM	EXOSC1 domain-containing protein. (185 aa)
	W4KNQ9_9AGAM	Uncharacterized protein. (65 aa)
	W4KP65_9AGAM	DNA helicase; Belongs to the MCM family. (839 aa)
	W4KPF2_9AGAM	AA_TRNA_LIGASE_II domain-containing protein. (545 aa)
	W4KR68_9AGAM	DNA helicase; Belongs to the MCM family. (747 aa)
	W4JMR7_9AGAM	AA_TRNA_LIGASE_II domain-containing protein. (573 aa)
	W4JRQ8_9AGAM	Putative 26S proteasome regulatory complex, ATPase RPT6; Belongs to the AAA ATPase family. (401 aa)
	W4JUK3_9AGAM	Uncharacterized protein. (124 aa)
	W4JUY3_9AGAM	DNA helicase; Belongs to the MCM family. (913 aa)
	W4JWK1_9AGAM	Uncharacterized protein. (108 aa)
	W4JXE4_9AGAM	S1 motif domain-containing protein. (334 aa)
	W4JY70_9AGAM	TRAM domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (563 aa)
	W4JYB9_9AGAM	Stn1 domain-containing protein. (487 aa)
	W4JYE7_9AGAM	Uncharacterized protein. (170 aa)
	W4K070_9AGAM	Uncharacterized protein. (220 aa)
	W4K0A8_9AGAM	S1 domain-containing protein. (284 aa)
	W4K0E2_9AGAM	Putative 26S proteasome regulatory complex, ATPase RPT4; Belongs to the AAA ATPase family. (399 aa)
	W4K0V0_9AGAM	DNA ligase. (1414 aa)
	W4K3G6_9AGAM	Eukaryotic translation initiation factor 5A. (161 aa)
	W4K3N3_9AGAM	DNA helicase; Belongs to the MCM family. (864 aa)
	W4K427_9AGAM	Zf-primase domain-containing protein. (816 aa)
	W4K4S7_9AGAM	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (145 aa)
	W4K5V1_9AGAM	Lysine--tRNA ligase. (584 aa)
	W4K6V1_9AGAM	Uncharacterized protein. (399 aa)
	W4K716_9AGAM	DNA ligase. (656 aa)
	W4K718_9AGAM	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (178 aa)
	W4K7B6_9AGAM	Uncharacterized protein. (230 aa)
	W4K9D0_9AGAM	26S proteasome regulatory complex, ATPase RPT5; Belongs to the AAA ATPase family. (459 aa)
	W4KBA8_9AGAM	Exoribonuclease. (959 aa)
	W4KBE4_9AGAM	26S proteasome regulatory complex, ATPase RPT2; Belongs to the AAA ATPase family. (449 aa)
	W4KBQ9_9AGAM	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (139 aa)
	W4KDD6_9AGAM	Ribosomal_L2_C domain-containing protein. (388 aa)
	W4KDT7_9AGAM	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. (1084 aa)
	W4KEA3_9AGAM	DNA helicase; Belongs to the MCM family. (963 aa)
	W4KET8_9AGAM	AA_TRNA_LIGASE_II domain-containing protein. (658 aa)
	W4KF50_9AGAM	Uncharacterized protein. (133 aa)
	W4KFC6_9AGAM	Ribosomal_L2_C domain-containing protein. (254 aa)
	W4KHU2_9AGAM	AA_TRNA_LIGASE_II domain-containing protein. (461 aa)
	W4KIE3_9AGAM	Uncharacterized protein. (73 aa)
	W4KIE5_9AGAM	AAA ATPase; Belongs to the AAA ATPase family. (453 aa)
	W4KJG5_9AGAM	OB domain-containing protein. (302 aa)
	W4KJN5_9AGAM	Putative exoribonuclease; Belongs to the RNR ribonuclease family. (998 aa)
	W4KJS4_9AGAM	Uncharacterized protein. (1090 aa)

Your Current Organism:

Heterobasidion irregulare

NCBI taxonomy Id: 747525
Other names: H. irregulare TC 32-1, Heterobasidion irregulare TC 32-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	W4JUY3_9AGAM	W4KL74	W4JUY3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	W4JYB9_9AGAM	W4KL74	W4JYB9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Stn1 domain-containing protein.	0.614
MCM7	W4K0V0_9AGAM	W4KL74	W4K0V0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.462
MCM7	W4K3N3_9AGAM	W4KL74	W4K3N3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	W4K427_9AGAM	W4KL74	W4K427	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Zf-primase domain-containing protein.	0.991
MCM7	W4K716_9AGAM	W4KL74	W4K716	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.635
MCM7	W4KEA3_9AGAM	W4KL74	W4KEA3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	W4KJG5_9AGAM	W4KL74	W4KJG5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	OB domain-containing protein.	0.739
MCM7	W4KKG5_9AGAM	W4KL74	W4KKG5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.739
MCM7	W4KLF0_9AGAM	W4KL74	W4KLF0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.612
MCM7	W4KMZ6_9AGAM	W4KL74	W4KMZ6	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.635
MCM7	W4KP65_9AGAM	W4KL74	W4KP65	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	W4KR68_9AGAM	W4KL74	W4KR68	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
W4JMR7_9AGAM	W4K5V1_9AGAM	W4JMR7	W4K5V1	AA_TRNA_LIGASE_II domain-containing protein.	Lysine--tRNA ligase.	0.792
W4JMR7_9AGAM	W4K6V1_9AGAM	W4JMR7	W4K6V1	AA_TRNA_LIGASE_II domain-containing protein.	Uncharacterized protein.	0.741
W4JMR7_9AGAM	W4KET8_9AGAM	W4JMR7	W4KET8	AA_TRNA_LIGASE_II domain-containing protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.461
W4JMR7_9AGAM	W4KHU2_9AGAM	W4JMR7	W4KHU2	AA_TRNA_LIGASE_II domain-containing protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.907
W4JMR7_9AGAM	W4KMS5_9AGAM	W4JMR7	W4KMS5	AA_TRNA_LIGASE_II domain-containing protein.	Uncharacterized protein.	0.679
W4JMR7_9AGAM	W4KPF2_9AGAM	W4JMR7	W4KPF2	AA_TRNA_LIGASE_II domain-containing protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.445
W4JRQ8_9AGAM	W4K0E2_9AGAM	W4JRQ8	W4K0E2	Putative 26S proteasome regulatory complex, ATPase RPT6; Belongs to the AAA ATPase family.	Putative 26S proteasome regulatory complex, ATPase RPT4; Belongs to the AAA ATPase family.	0.999