(33 nodes) ATPase, nucleotide binding domain network (Heterobasidion irregulare)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	arp3	Actin-related protein 3; Belongs to the actin family. (431 aa)
	W4JMQ7_9AGAM	Uncharacterized protein; Belongs to the heat shock protein 70 family. (666 aa)
	W4JPC8_9AGAM	BcrAD_BadFG domain-containing protein. (395 aa)
	W4JRE5_9AGAM	Uncharacterized protein. (94 aa)
	W4JTP2_9AGAM	Uncharacterized protein. (768 aa)
	W4JX14_9AGAM	Phosphotransferase. (496 aa)
	W4JZ01_9AGAM	Uncharacterized protein; Belongs to the FGGY kinase family. (536 aa)
	W4JZT6_9AGAM	Uncharacterized protein; Belongs to the actin family. (727 aa)
	W4K038_9AGAM	Uncharacterized protein; Belongs to the heat shock protein 70 family. (634 aa)
	W4K068_9AGAM	Uncharacterized protein. (544 aa)
	W4K0N4_9AGAM	Uncharacterized protein; Belongs to the actin family. (519 aa)
	W4K143_9AGAM	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (391 aa)
	W4K1J0_9AGAM	Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (638 aa)
	W4K1W3_9AGAM	Uncharacterized protein. (709 aa)
	W4K1Z5_9AGAM	Uncharacterized protein. (281 aa)
	W4K2B1_9AGAM	Uncharacterized protein; Belongs to the heat shock protein 70 family. (675 aa)
	W4K3D8_9AGAM	Uncharacterized protein. (1048 aa)
	W4K3Q6_9AGAM	tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. (391 aa)
	W4K4Z5_9AGAM	Uncharacterized protein. (595 aa)
	W4K5V6_9AGAM	Uncharacterized protein. (774 aa)
	W4K7Z0_9AGAM	Uncharacterized protein; Belongs to the actin family. (446 aa)
	W4KBS8_9AGAM	Uncharacterized protein. (606 aa)
	W4KEC2_9AGAM	Uncharacterized protein; Belongs to the actin family. (592 aa)
	arp4	Actin-related protein 4; Belongs to the actin family. (437 aa)
	W4KF04_9AGAM	Uncharacterized protein. (576 aa)
	act1.1	Actin 1.1. (375 aa)
	W4KGR5_9AGAM	Phosphotransferase. (540 aa)
	act1.2	Actin 1.2. (375 aa)
	W4KI26_9AGAM	Uncharacterized protein; Belongs to the heat shock protein 70 family. (612 aa)
	W4KJD9_9AGAM	Uncharacterized protein; Belongs to the heat shock protein 70 family. (654 aa)
	W4KMC9_9AGAM	Uncharacterized protein. (488 aa)
	W4KQ95_9AGAM	Uncharacterized protein; Belongs to the actin family. (378 aa)
	KAE1	tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (366 aa)

Your Current Organism:

Heterobasidion irregulare

NCBI taxonomy Id: 747525
Other names: H. irregulare TC 32-1, Heterobasidion irregulare TC 32-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KAE1	W4K3Q6_9AGAM	W4KQL2	W4K3Q6	tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...]	tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.	0.463
W4JMQ7_9AGAM	W4JRE5_9AGAM	W4JMQ7	W4JRE5	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.590
W4JMQ7_9AGAM	W4K038_9AGAM	W4JMQ7	W4K038	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.674
W4JMQ7_9AGAM	W4K1W3_9AGAM	W4JMQ7	W4K1W3	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.575
W4JMQ7_9AGAM	W4K1Z5_9AGAM	W4JMQ7	W4K1Z5	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.543
W4JMQ7_9AGAM	W4K2B1_9AGAM	W4JMQ7	W4K2B1	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.606
W4JMQ7_9AGAM	W4K4Z5_9AGAM	W4JMQ7	W4K4Z5	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.575
W4JMQ7_9AGAM	W4K5V6_9AGAM	W4JMQ7	W4K5V6	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.899
W4JMQ7_9AGAM	W4KBS8_9AGAM	W4JMQ7	W4KBS8	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.575
W4JMQ7_9AGAM	W4KI26_9AGAM	W4JMQ7	W4KI26	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.615
W4JMQ7_9AGAM	W4KJD9_9AGAM	W4JMQ7	W4KJD9	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.613
W4JRE5_9AGAM	W4JMQ7_9AGAM	W4JRE5	W4JMQ7	Uncharacterized protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.590
W4JRE5_9AGAM	W4K038_9AGAM	W4JRE5	W4K038	Uncharacterized protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.587
W4JRE5_9AGAM	W4K1W3_9AGAM	W4JRE5	W4K1W3	Uncharacterized protein.	Uncharacterized protein.	0.538
W4JRE5_9AGAM	W4K1Z5_9AGAM	W4JRE5	W4K1Z5	Uncharacterized protein.	Uncharacterized protein.	0.829
W4JRE5_9AGAM	W4K4Z5_9AGAM	W4JRE5	W4K4Z5	Uncharacterized protein.	Uncharacterized protein.	0.538
W4JRE5_9AGAM	W4K5V6_9AGAM	W4JRE5	W4K5V6	Uncharacterized protein.	Uncharacterized protein.	0.668
W4JRE5_9AGAM	W4KBS8_9AGAM	W4JRE5	W4KBS8	Uncharacterized protein.	Uncharacterized protein.	0.538
W4JRE5_9AGAM	W4KI26_9AGAM	W4JRE5	W4KI26	Uncharacterized protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.779
W4JRE5_9AGAM	W4KJD9_9AGAM	W4JRE5	W4KJD9	Uncharacterized protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.587