60 items (Heterobasidion irregulare) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W4KP55_9AGAM	Uncharacterized protein. (1017 aa)
	W4JQ66_9AGAM	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (146 aa)
	W4JQG5_9AGAM	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (977 aa)
	W4JR22_9AGAM	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
	W4JRG4_9AGAM	Uncharacterized protein. (402 aa)
	W4JT85_9AGAM	Mitochondrial outer membrane translocase receptor, subunit TOM70. (575 aa)
	W4JTE0_9AGAM	Non-specific serine/threonine protein kinase. (1253 aa)
	W4JUJ5_9AGAM	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (328 aa)
	W4JUW2_9AGAM	Uncharacterized protein. (193 aa)
	W4JVJ9_9AGAM	DUF3543 domain-containing protein. (424 aa)
	W4JVU5_9AGAM	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (339 aa)
	W4JW41_9AGAM	Uncharacterized protein. (1604 aa)
	W4JW96_9AGAM	Uncharacterized protein. (446 aa)
	W4JY72_9AGAM	Uncharacterized protein. (129 aa)
	W4JYT1_9AGAM	Ubiquitin-like domain-containing protein. (159 aa)
	W4JYV8_9AGAM	ATG11 domain-containing protein. (1096 aa)
	W4JZZ2_9AGAM	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (982 aa)
	ubc1	Ubiquitin-conjugating enzyme1. (129 aa)
	W4K0B5_9AGAM	Phosphatidylinositol 3-kinase VPS34. (830 aa)
	W4K1G8_9AGAM	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (3066 aa)
	W4KBC7_9AGAM	DJ-1_PfpI domain-containing protein. (217 aa)
	W4K9Y9_9AGAM	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (290 aa)
	W4K9V8_9AGAM	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (861 aa)
	W4K8E5_9AGAM	Uncharacterized protein. (193 aa)
	W4K8E4_9AGAM	Cysteine peptidase C56. (226 aa)
	W4K869_9AGAM	AMPKBI domain-containing protein. (248 aa)
	W4K830_9AGAM	AMPKBI domain-containing protein. (321 aa)
	W4K7U5_9AGAM	Uncharacterized protein. (155 aa)
	W4K7P2_9AGAM	Autophagy-related protein 3. (369 aa)
	W4K733_9AGAM	Peroxisome targeting signal receptor Pex5. (379 aa)
	W4K6M4_9AGAM	Uncharacterized protein. (326 aa)
	W4K6A6_9AGAM	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (673 aa)
	W4K624_9AGAM	Uncharacterized protein. (338 aa)
	W4K462_9AGAM	Peroxisome targeting sequence binding protein Pex5. (287 aa)
	W4KD74_9AGAM	Translocase of outer mitochondrial membrane complex, subunit TOM7. (51 aa)
	W4KD09_9AGAM	Uncharacterized protein. (561 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (742 aa)
	W4KDK9_9AGAM	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (412 aa)
	W4KEW0_9AGAM	Autophagy_act_C domain-containing protein. (230 aa)
	W4KF85_9AGAM	Uncharacterized protein. (216 aa)
	W4KFG5_9AGAM	WD_REPEATS_REGION domain-containing protein. (466 aa)
	W4KFL9_9AGAM	Uncharacterized protein. (219 aa)
	W4KG20_9AGAM	Translocase of outer mitochondrial membrane complex, subunit TOM20. (563 aa)
	W4KGN1_9AGAM	Uncharacterized protein; Belongs to the peptidase C19 family. (707 aa)
	W4KHA7_9AGAM	Uncharacterized protein. (982 aa)
	W4KIJ6_9AGAM	Autophagy-related protein. (127 aa)
	W4KJ78_9AGAM	Uncharacterized protein. (156 aa)
	W4KJR4_9AGAM	Uncharacterized protein. (465 aa)
	W4KJU0_9AGAM	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (843 aa)
	W4KJU7_9AGAM	Uncharacterized protein. (249 aa)
	W4KKG8_9AGAM	Myotubularin phosphatase domain-containing protein. (901 aa)
	W4KKQ8_9AGAM	Uncharacterized protein. (182 aa)
	W4KL83_9AGAM	Uncharacterized protein. (165 aa)
	W4KLI5_9AGAM	Translocase of outer mitochondrial membrane complex, subunit TOM40. (355 aa)
	W4KLT3_9AGAM	Uncharacterized protein. (1591 aa)
	W4KMA5_9AGAM	Fungal_trans domain-containing protein. (691 aa)
	W4KNT3_9AGAM	Non-specific serine/threonine protein kinase. (641 aa)
	W4KNU1_9AGAM	ATG16 domain-containing protein. (281 aa)
	W4KP11_9AGAM	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (343 aa)
	W4KQP6_9AGAM	Uncharacterized protein. (207 aa)

Your Current Organism:

Heterobasidion irregulare

NCBI taxonomy Id: 747525
Other names: H. irregulare TC 32-1, Heterobasidion irregulare TC 32-1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MDM34	W4K9V8_9AGAM	W4KCY9	W4K9V8	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.535
MDM34	W4K9Y9_9AGAM	W4KCY9	W4K9Y9	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.865
MDM34	W4KD74_9AGAM	W4KCY9	W4KD74	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Translocase of outer mitochondrial membrane complex, subunit TOM7.	0.560
MDM34	W4KDK9_9AGAM	W4KCY9	W4KDK9	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.865
MDM34	W4KG20_9AGAM	W4KCY9	W4KG20	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Translocase of outer mitochondrial membrane complex, subunit TOM20.	0.447
MDM34	W4KJ78_9AGAM	W4KCY9	W4KJ78	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Uncharacterized protein.	0.604
W4JQ66_9AGAM	W4JQG5_9AGAM	W4JQ66	W4JQG5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily.	0.503
W4JQ66_9AGAM	W4JRG4_9AGAM	W4JQ66	W4JRG4	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Uncharacterized protein.	0.931
W4JQ66_9AGAM	W4JUJ5_9AGAM	W4JQ66	W4JUJ5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	0.999
W4JQ66_9AGAM	W4JVJ9_9AGAM	W4JQ66	W4JVJ9	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	DUF3543 domain-containing protein.	0.883
W4JQ66_9AGAM	W4JVU5_9AGAM	W4JQ66	W4JVU5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.883
W4JQ66_9AGAM	W4JW41_9AGAM	W4JQ66	W4JW41	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Uncharacterized protein.	0.839
W4JQ66_9AGAM	W4JY72_9AGAM	W4JQ66	W4JY72	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Uncharacterized protein.	0.470
W4JQ66_9AGAM	W4JYV8_9AGAM	W4JQ66	W4JYV8	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	ATG11 domain-containing protein.	0.470
W4JQ66_9AGAM	W4JZZ2_9AGAM	W4JQ66	W4JZZ2	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.	0.631
W4JQ66_9AGAM	W4K0B5_9AGAM	W4JQ66	W4K0B5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Phosphatidylinositol 3-kinase VPS34.	0.842
W4JQ66_9AGAM	W4K624_9AGAM	W4JQ66	W4K624	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Uncharacterized protein.	0.864
W4JQ66_9AGAM	W4K6A6_9AGAM	W4JQ66	W4K6A6	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.999
W4JQ66_9AGAM	W4K6M4_9AGAM	W4JQ66	W4K6M4	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Uncharacterized protein.	0.953
W4JQ66_9AGAM	W4K7P2_9AGAM	W4JQ66	W4K7P2	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Autophagy-related protein 3.	0.995