(59 nodes) Preribosome, large subunit precursor, and Ribosomal large subunit biogenesis network (Melampsora laricipopulina)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F4R3S4_MELLP	ATP-dependent RNA helicase DBP10. (966 aa)
	F4R5E6_MELLP	Protein MAK16; Belongs to the MAK16 family. (271 aa)
	F4R5R8_MELLP	RNA helicase. (631 aa)
	F4R5S3_MELLP	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (549 aa)
	F4R704_MELLP	RRM domain-containing protein. (960 aa)
	F4RAD9_MELLP	Uncharacterized protein. (319 aa)
	F4RBU4_MELLP	C2H2-type domain-containing protein. (154 aa)
	F4RBZ0_MELLP	Brix domain-containing protein. (306 aa)
	F4RC18_MELLP	Uncharacterized protein. (60 aa)
	F4RCN4_MELLP	Uncharacterized protein. (640 aa)
	F4RCV3_MELLP	Uncharacterized protein; Belongs to the DEAD box helicase family. (525 aa)
	F4REV1_MELLP	WD_REPEATS_REGION domain-containing protein. (513 aa)
	F4RFA2_MELLP	CP-type G domain-containing protein. (669 aa)
	F4RG82_MELLP	Uncharacterized protein. (260 aa)
	F4RGW4_MELLP	Uncharacterized protein. (775 aa)
	F4RHC2_MELLP	Uncharacterized protein. (867 aa)
	F4RIE1_MELLP	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (375 aa)
	F4RII6_MELLP	Uncharacterized protein. (267 aa)
	F4RJC4_MELLP	Uncharacterized protein. (280 aa)
	F4RKP3_MELLP	Brix domain-containing protein. (343 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (662 aa)
	F4RL43_MELLP	RNA helicase. (530 aa)
	F4RM18_MELLP	WD_REPEATS_REGION domain-containing protein. (511 aa)
	F4RMJ8_MELLP	Peptidase_M24 domain-containing protein. (403 aa)
	F4RNF0_MELLP	Uncharacterized protein. (447 aa)
	F4RNV4_MELLP	Uncharacterized protein; Belongs to the DEAD box helicase family. (573 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (463 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (884 aa)
	F4RPJ5_MELLP	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	F4RRE4_MELLP	Uncharacterized protein. (668 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (267 aa)
	F4RRX0_MELLP	Uncharacterized protein. (200 aa)
	F4RT85_MELLP	Uncharacterized protein; Belongs to the DEAD box helicase family. (521 aa)
	F4RTD6_MELLP	Uncharacterized protein. (397 aa)
	F4RUP5_MELLP	Uncharacterized protein. (167 aa)
	F4RUP6_MELLP	CP-type G domain-containing protein. (477 aa)
	F4RVB0_MELLP	Uncharacterized protein. (239 aa)
	F4RVJ3_MELLP	Uncharacterized protein. (774 aa)
	F4RXR3_MELLP	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (425 aa)
	F4RYV0_MELLP	Brix domain-containing protein. (518 aa)
	F4RZC0_MELLP	Uncharacterized protein. (920 aa)
	F4RZX8_MELLP	TRASH domain-containing protein. (238 aa)
	F4S0H5_MELLP	rRNA-processing protein; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit. Belongs to the CGR1 family. (101 aa)
	F4S0X0_MELLP	Uncharacterized protein. (510 aa)
	F4S1F4_MELLP	Uncharacterized protein. (478 aa)
	F4S393_MELLP	Brix domain-containing protein. (392 aa)
	F4S409_MELLP	Uncharacterized protein. (124 aa)
	F4S472_MELLP	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (701 aa)
	F4S544_MELLP	Uncharacterized protein. (456 aa)
	F4S5K1_MELLP	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (468 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (642 aa)
	F4S7Y6_MELLP	Uncharacterized protein. (834 aa)
	F4S903_MELLP	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (234 aa)
	F4S9M0_MELLP	RRM domain-containing protein. (403 aa)
	F4SA09_MELLP	Uncharacterized protein; Belongs to the DEAD box helicase family. (503 aa)
	F4SAX2_MELLP	Uncharacterized protein. (718 aa)
	F4SB67_MELLP	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (768 aa)
	F4SBJ3_MELLP	G domain-containing protein. (320 aa)
	F4SBX0_MELLP	RNA helicase. (659 aa)

Your Current Organism:

Melampsora laricipopulina

NCBI taxonomy Id: 747676
Other names: M. larici-populina 98AG31, Melampsora larici-populina 98AG31, Melampsora laricis-populina 98AG31

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERB1	F4R3S4_MELLP	F4RL26	F4R3S4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	ATP-dependent RNA helicase DBP10.	0.986
ERB1	F4R5E6_MELLP	F4RL26	F4R5E6	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein MAK16; Belongs to the MAK16 family.	0.981
ERB1	F4R5R8_MELLP	F4RL26	F4R5R8	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA helicase.	0.899
ERB1	F4R5S3_MELLP	F4RL26	F4R5S3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.	0.871
ERB1	F4R704_MELLP	F4RL26	F4R704	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RRM domain-containing protein.	0.912
ERB1	F4RAD9_MELLP	F4RL26	F4RAD9	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.824
ERB1	F4RBU4_MELLP	F4RL26	F4RBU4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	C2H2-type domain-containing protein.	0.605
ERB1	F4RBZ0_MELLP	F4RL26	F4RBZ0	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Brix domain-containing protein.	0.997
ERB1	F4RC18_MELLP	F4RL26	F4RC18	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.720
ERB1	F4RCN4_MELLP	F4RL26	F4RCN4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.976
ERB1	F4RCV3_MELLP	F4RL26	F4RCV3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.927
ERB1	F4REV1_MELLP	F4RL26	F4REV1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.917
ERB1	F4RFA2_MELLP	F4RL26	F4RFA2	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	CP-type G domain-containing protein.	0.901
ERB1	F4RG82_MELLP	F4RL26	F4RG82	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.897
ERB1	F4RGW4_MELLP	F4RL26	F4RGW4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.939
ERB1	F4RHC2_MELLP	F4RL26	F4RHC2	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.994
ERB1	F4RIE1_MELLP	F4RL26	F4RIE1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.797
ERB1	F4RII6_MELLP	F4RL26	F4RII6	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.994
ERB1	F4RJC4_MELLP	F4RL26	F4RJC4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.993
ERB1	F4RKP3_MELLP	F4RL26	F4RKP3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Brix domain-containing protein.	0.990