73 items (Melampsora laricipopulina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F4RQS4_MELLP	Uncharacterized protein. (804 aa)
	F4RST5_MELLP	DUF4211 domain-containing protein. (460 aa)
	F4RSU9_MELLP	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (700 aa)
	F4RTH6_MELLP	RPOL4c domain-containing protein. (130 aa)
	F4RU01_MELLP	TAFII28 domain-containing protein. (227 aa)
	F4RUC3_MELLP	Acyl_transf_3 domain-containing protein. (492 aa)
	F4RVA9_MELLP	Uncharacterized protein. (838 aa)
	F4RW68_MELLP	Acyl_transf_3 domain-containing protein. (473 aa)
	F4RWC7_MELLP	TFIID_20kDa domain-containing protein. (124 aa)
	F4RY07_MELLP	Uncharacterized protein. (63 aa)
	F4RY48_MELLP	RPOLD domain-containing protein. (359 aa)
	F4RY69_MELLP	Nuclear cap-binding protein subunit 2. (209 aa)
	F4RYV1_MELLP	Peptidase_M24 domain-containing protein. (674 aa)
	F4RYV2_MELLP	FACT-Spt16_Nlob domain-containing protein. (166 aa)
	F4RYV5_MELLP	FACT-Spt16_Nlob domain-containing protein. (586 aa)
	F4RZ31_MELLP	RNA_pol_Rpb5_C domain-containing protein. (67 aa)
	F4RZL2_MELLP	Uncharacterized protein. (50 aa)
	F4RZV5_MELLP	CYCLIN domain-containing protein; Belongs to the cyclin family. (203 aa)
	F4S137_MELLP	Uncharacterized protein. (316 aa)
	F4S1K7_MELLP	CDC73_C domain-containing protein. (407 aa)
	F4S221_MELLP	Acyl_transf_3 domain-containing protein. (431 aa)
	F4S238_MELLP	Uncharacterized protein. (70 aa)
	F4S2F9_MELLP	S1 motif domain-containing protein. (172 aa)
	F4S360_MELLP	TFIIS N-terminal domain-containing protein. (400 aa)
	F4S3T6_MELLP	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (107 aa)
	F4R4S3_MELLP	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (454 aa)
	F4R467_MELLP	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (529 aa)
	F4R4R7_MELLP	Uncharacterized protein. (72 aa)
	F4R508_MELLP	Plus3 domain-containing protein. (554 aa)
	F4R509_MELLP	Transcription initiation factor TFIID subunit 9. (216 aa)
	F4R5C8_MELLP	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (362 aa)
	F4R7M3_MELLP	Uncharacterized protein. (142 aa)
	F4R8Q1_MELLP	Uncharacterized protein. (67 aa)
	F4SA93_MELLP	DUF3591 domain-containing protein. (1119 aa)
	F4S9X8_MELLP	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1786 aa)
	F4S8G9_MELLP	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (122 aa)
	F4S824_MELLP	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (247 aa)
	F4S6W4_MELLP	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1598 aa)
	F4S6R3_MELLP	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (128 aa)
	F4S620_MELLP	RING-type domain-containing protein. (171 aa)
	F4R997_MELLP	PHD-type domain-containing protein. (1472 aa)
	F4RB28_MELLP	Uncharacterized protein. (290 aa)
	F4RB56_MELLP	Uncharacterized protein. (169 aa)
	F4RBH3_MELLP	Uncharacterized protein. (454 aa)
	F4RBN5_MELLP	Uncharacterized protein. (437 aa)
	F4RBP8_MELLP	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1212 aa)
	F4RCL4_MELLP	Uncharacterized protein. (378 aa)
	F4RCY1_MELLP	TAFII55_N domain-containing protein. (329 aa)
	F4RCY2_MELLP	Uncharacterized protein. (482 aa)
	F4RD40_MELLP	TAF domain-containing protein. (562 aa)
	F4RDR3_MELLP	Acyl_transf_3 domain-containing protein. (488 aa)
	F4RF39_MELLP	Uncharacterized protein. (736 aa)
	F4RF42_MELLP	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1257 aa)
	F4RFK1_MELLP	BTB domain-containing protein. (878 aa)
	F4RFN0_MELLP	Uncharacterized protein; Belongs to the cyclin family. (493 aa)
	F4RFN8_MELLP	Uncharacterized protein. (1078 aa)
	F4RFP0_MELLP	RNA_pol_L_2 domain-containing protein. (159 aa)
	F4RHZ9_MELLP	Uncharacterized protein. (83 aa)
	F4RI66_MELLP	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (455 aa)
	F4RIW9_MELLP	Uncharacterized protein. (881 aa)
	F4RJK6_MELLP	Uncharacterized protein. (187 aa)
	F4RJV1_MELLP	CYCLIN domain-containing protein; Belongs to the cyclin family. (314 aa)
	F4RKB9_MELLP	Uncharacterized protein. (180 aa)
	F4RKL8_MELLP	TFIIB-type domain-containing protein. (345 aa)
	F4RKX6_MELLP	HTH TFE/IIEalpha-type domain-containing protein. (478 aa)
	F4RKY9_MELLP	Uncharacterized protein. (356 aa)
	F4RMD6_MELLP	Uncharacterized protein. (50 aa)
	F4RMF2_MELLP	Uncharacterized protein. (1024 aa)
	F4RMH4_MELLP	Uncharacterized protein. (1102 aa)
	F4RMR2_MELLP	Uncharacterized protein. (456 aa)
	F4RQ80_MELLP	Uncharacterized protein. (233 aa)
	F4RQE5_MELLP	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (310 aa)
	F4RRW8_MELLP	Helicase ATP-binding domain-containing protein. (795 aa)

Your Current Organism:

Melampsora laricipopulina

NCBI taxonomy Id: 747676
Other names: M. larici-populina 98AG31, Melampsora larici-populina 98AG31, Melampsora laricis-populina 98AG31

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F4R467_MELLP	F4R4R7_MELLP	F4R467	F4R4R7	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.959
F4R467_MELLP	F4R508_MELLP	F4R467	F4R508	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Plus3 domain-containing protein.	0.993
F4R467_MELLP	F4R5C8_MELLP	F4R467	F4R5C8	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.698
F4R467_MELLP	F4R7M3_MELLP	F4R467	F4R7M3	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.966
F4R467_MELLP	F4R8Q1_MELLP	F4R467	F4R8Q1	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.962
F4R467_MELLP	F4RB56_MELLP	F4R467	F4RB56	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.663
F4R467_MELLP	F4RBH3_MELLP	F4R467	F4RBH3	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.997
F4R467_MELLP	F4RBP8_MELLP	F4R467	F4RBP8	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.988
F4R467_MELLP	F4RCL4_MELLP	F4R467	F4RCL4	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.922
F4R467_MELLP	F4RCY2_MELLP	F4R467	F4RCY2	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.869
F4R467_MELLP	F4RF39_MELLP	F4R467	F4RF39	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.663
F4R467_MELLP	F4RF42_MELLP	F4R467	F4RF42	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.966
F4R467_MELLP	F4RFN0_MELLP	F4R467	F4RFN0	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein; Belongs to the cyclin family.	0.652
F4R467_MELLP	F4RFN8_MELLP	F4R467	F4RFN8	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.967
F4R467_MELLP	F4RFP0_MELLP	F4R467	F4RFP0	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	RNA_pol_L_2 domain-containing protein.	0.962
F4R467_MELLP	F4RIW9_MELLP	F4R467	F4RIW9	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.662
F4R467_MELLP	F4RKY9_MELLP	F4R467	F4RKY9	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.670
F4R467_MELLP	F4RMD6_MELLP	F4R467	F4RMD6	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.648
F4R467_MELLP	F4RMF2_MELLP	F4R467	F4RMF2	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.429
F4R467_MELLP	F4RMH4_MELLP	F4R467	F4RMH4	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.997