(23 nodes) Bacterial-type flagellum organization network (Azoarcus sp. KH32C)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	flhC	Transcriptional activator; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (183 aa)
	frdC	Fumarate reductase, subunit C. (135 aa)
	lfgN	Putative chaperon of flagellar synthesis. (157 aa)
	flgM	Putative negative regulator of flagellin synthesis. (98 aa)
	flgA	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (236 aa)
	flgD	Basal-body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein. (225 aa)
	flgJ	Peptidoglycan hydrolase. (346 aa)
	flgK	Flagellar hook-filament junction protein 1. (482 aa)
	fliR	Flagellar biosynthesis protein; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (266 aa)
	fliQ	Flagellar biosynthesis protein; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa)
	fliP	Flagellar biosynthesis protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (253 aa)
	fliO	Flagellar biosynthesis protein. (140 aa)
	fliK	Flagellar hook-length control protein. (510 aa)
	fliJ	Flagellar protein. (151 aa)
	fliI	Flagellar-specific ATP synthase. (467 aa)
	fliS	Flagellar protein. (137 aa)
	AZKH_1516	Hypothetical protein. (1919 aa)
	flhD	Flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (106 aa)
	AZKH_3362	Hypothetical protein. (257 aa)
	AZKH_3464	Hypothetical protein. (151 aa)
	flhF	Flagellar biosynthesis regulator. (516 aa)
	flhA	Flagellar biosynthesis protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (702 aa)
	fliW	Flagellar assembly protein; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. (147 aa)

Your Current Organism:

Azoarcus sp. KH32C

NCBI taxonomy Id: 748247
Other names: A. sp. KH32C

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
flgA	flgD	AZKH_1305	AZKH_1308	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Basal-body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.	0.988
flgA	flgJ	AZKH_1305	AZKH_1314	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Peptidoglycan hydrolase.	0.993
flgA	flgK	AZKH_1305	AZKH_1315	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Flagellar hook-filament junction protein 1.	0.971
flgA	flgM	AZKH_1305	AZKH_1304	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Putative negative regulator of flagellin synthesis.	0.965
flgA	flhA	AZKH_1305	AZKH_3512	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Flagellar biosynthesis protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.	0.781
flgA	flhC	AZKH_1305	AZKH_3275	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Transcriptional activator; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.	0.676
flgA	flhD	AZKH_1305	AZKH_3276	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.	0.666
flgA	flhF	AZKH_1305	AZKH_3511	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Flagellar biosynthesis regulator.	0.906
flgA	fliI	AZKH_1305	AZKH_1327	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Flagellar-specific ATP synthase.	0.854
flgA	fliJ	AZKH_1305	AZKH_1326	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Flagellar protein.	0.896
flgA	fliK	AZKH_1305	AZKH_1325	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Flagellar hook-length control protein.	0.937
flgA	fliO	AZKH_1305	AZKH_1321	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Flagellar biosynthesis protein.	0.968
flgA	fliP	AZKH_1305	AZKH_1320	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Flagellar biosynthesis protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.	0.940
flgA	fliQ	AZKH_1305	AZKH_1319	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Flagellar biosynthesis protein; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.	0.909
flgA	fliR	AZKH_1305	AZKH_1318	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Flagellar biosynthesis protein; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.	0.814
flgA	fliS	AZKH_1305	AZKH_1426	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Flagellar protein.	0.887
flgA	lfgN	AZKH_1305	AZKH_1303	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	Putative chaperon of flagellar synthesis.	0.948
flgD	flgA	AZKH_1308	AZKH_1305	Basal-body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.	Chaperon for flagellar basal body P-ring formation; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.	0.988
flgD	flgJ	AZKH_1308	AZKH_1314	Basal-body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.	Peptidoglycan hydrolase.	0.991
flgD	flgK	AZKH_1308	AZKH_1315	Basal-body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.	Flagellar hook-filament junction protein 1.	0.985