(5 nodes) Histidine biosynthesis protein, and Phosphoribosyl-ATP pyrophosphohydrolase-like network (Pseudogulbenkiania sp. NH8B)

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Your Input:
	hisE	phosphoribosyl-ATP diphosphatase; K01523. (108 aa)
	hisI	phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (128 aa)
	hisF	Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (255 aa)
	hisA	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; K01814. (246 aa)
	hisH	Imidazoleglycerol-phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (213 aa)

Your Current Organism:

Pseudogulbenkiania sp. NH8B

NCBI taxonomy Id: 748280
Other names: P. sp. NH8B

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
hisA	hisE	NH8B_3829	NH8B_3826	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; K01814.	phosphoribosyl-ATP diphosphatase; K01523.	0.987
hisA	hisF	NH8B_3829	NH8B_3828	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; K01814.	Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	0.997
hisA	hisH	NH8B_3829	NH8B_3830	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; K01814.	Imidazoleglycerol-phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.999
hisA	hisI	NH8B_3829	NH8B_3827	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; K01814.	phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.	0.999
hisE	hisA	NH8B_3826	NH8B_3829	phosphoribosyl-ATP diphosphatase; K01523.	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; K01814.	0.987
hisE	hisF	NH8B_3826	NH8B_3828	phosphoribosyl-ATP diphosphatase; K01523.	Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	0.989
hisE	hisH	NH8B_3826	NH8B_3830	phosphoribosyl-ATP diphosphatase; K01523.	Imidazoleglycerol-phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.983
hisE	hisI	NH8B_3826	NH8B_3827	phosphoribosyl-ATP diphosphatase; K01523.	phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.	0.999
hisF	hisA	NH8B_3828	NH8B_3829	Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; K01814.	0.997
hisF	hisE	NH8B_3828	NH8B_3826	Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	phosphoribosyl-ATP diphosphatase; K01523.	0.989
hisF	hisH	NH8B_3828	NH8B_3830	Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	Imidazoleglycerol-phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.999
hisF	hisI	NH8B_3828	NH8B_3827	Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.	0.999
hisH	hisA	NH8B_3830	NH8B_3829	Imidazoleglycerol-phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; K01814.	0.999
hisH	hisE	NH8B_3830	NH8B_3826	Imidazoleglycerol-phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	phosphoribosyl-ATP diphosphatase; K01523.	0.983
hisH	hisF	NH8B_3830	NH8B_3828	Imidazoleglycerol-phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	0.999
hisH	hisI	NH8B_3830	NH8B_3827	Imidazoleglycerol-phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.	0.990
hisI	hisA	NH8B_3827	NH8B_3829	phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; K01814.	0.999
hisI	hisE	NH8B_3827	NH8B_3826	phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.	phosphoribosyl-ATP diphosphatase; K01523.	0.999
hisI	hisF	NH8B_3827	NH8B_3828	phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.	Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	0.999
hisI	hisH	NH8B_3827	NH8B_3830	phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.	Imidazoleglycerol-phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.990