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pdxA pdxA NH8B_0320 NH8B_0320 NH8B_0410 NH8B_0410 NH8B_0413 NH8B_0413 NH8B_0457 NH8B_0457 NH8B_0679 NH8B_0679 NH8B_0680 NH8B_0680 aroE aroE fabG fabG tdh tdh NH8B_0886 NH8B_0886 mdh mdh ribD ribD NH8B_1101 NH8B_1101 NH8B_1216 NH8B_1216 NH8B_1227 NH8B_1227 fabG-2 fabG-2 NH8B_1367 NH8B_1367 leuB leuB NH8B_1504 NH8B_1504 benD benD mmsB-2 mmsB-2 NH8B_2011 NH8B_2011 NH8B_2169 NH8B_2169 NH8B_2338 NH8B_2338 NH8B_2455 NH8B_2455 NH8B_2503 NH8B_2503 NH8B_2506 NH8B_2506 NH8B_2527 NH8B_2527 NH8B_2532 NH8B_2532 dxr dxr NH8B_2631 NH8B_2631 NH8B_2713 NH8B_2713 NH8B_2826 NH8B_2826 mmsB-4 mmsB-4 NH8B_2960 NH8B_2960 murB murB guaB guaB NH8B_3221 NH8B_3221 fabG-3 fabG-3 NH8B_3287 NH8B_3287 NH8B_3370 NH8B_3370 NH8B_3379 NH8B_3379 gpsA gpsA NH8B_3486 NH8B_3486 NH8B_3539 NH8B_3539 fcl fcl NH8B_3694 NH8B_3694 NH8B_0252 NH8B_0252 NH8B_0220 NH8B_0220 zwf zwf lcdH lcdH NH8B_0020 NH8B_0020 NH8B_3755 NH8B_3755 hisD hisD ilvC ilvC NH8B_4089 NH8B_4089
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (332 aa)
NH8B_0320Short-chain dehydrogenase/reductase SDR. (248 aa)
NH8B_0410Pteridine reductase; K03793. (259 aa)
NH8B_0413Oxidoreductase domain protein. (354 aa)
NH8B_0457Formaldehyde dehydrogenase, glutathione-independent; K00148. (398 aa)
NH8B_0679Isocitrate dehydrogenase, NADP-dependent; K00031. (414 aa)
NH8B_0680Isocitrate dehydrogenase, NADP-dependent; K00031; Belongs to the monomeric-type IDH family. (745 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (273 aa)
fabG3-oxoacyl-(acyl-carrier protein) reductase; K00059. (246 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (343 aa)
NH8B_0886Short-chain dehydrogenase/reductase SDR. (250 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (325 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (364 aa)
NH8B_1101malate/L-lactate dehydrogenase; K00016; Belongs to the LDH2/MDH2 oxidoreductase family. (358 aa)
NH8B_1216dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (297 aa)
NH8B_1227Oxidoreductase, NAD-binding. (353 aa)
fabG-23-oxoacyl-(acyl-carrier protein) reductase; K00059. (239 aa)
NH8B_1367S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase. (372 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (354 aa)
NH8B_1504D-3-phosphoglycerate dehydrogenase; K00058; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa)
benD1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; K05783; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)
mmsB-23-hydroxyisobutyrate dehydrogenase; K00020; Belongs to the HIBADH-related family. (298 aa)
NH8B_20113-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase; K07516. (788 aa)
NH8B_21693-hydroxybutyryl-CoA dehydrogenase; K00074. (271 aa)
NH8B_2338acetoacetyl-CoA reductase; K00023. (245 aa)
NH8B_2455Alcohol dehydrogenase, zinc-binding. (363 aa)
NH8B_2503Shikimate dehydrogenase substrate binding domain protein; K00014. (277 aa)
NH8B_2506D-3-phosphoglycerate dehydrogenase; K00058; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (338 aa)
NH8B_2527Short-chain dehydrogenase/reductase SDR. (258 aa)
NH8B_2532Shikimate dehydrogenase substrate binding domain protein; K00014. (292 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (335 aa)
NH8B_26313-hydroxyacyl-CoA dehydrogenase, NAD-binding; K07516. (791 aa)
NH8B_2713Short-chain dehydrogenase/reductase SDR. (249 aa)
NH8B_28263-hydroxybutyryl-CoA dehydrogenase; K00074. (283 aa)
mmsB-43-hydroxyisobutyrate dehydrogenase; K00020; Belongs to the HIBADH-related family. (295 aa)
NH8B_2960D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding. (307 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (342 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (487 aa)
NH8B_3221UDP-glucose 6-dehydrogenase; K00012. (439 aa)
fabG-33-oxoacyl-(acyl-carrier protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
NH8B_32876-phosphogluconate dehydrogenase-like protein; K00033. (246 aa)
NH8B_3370Protein of unknown function; DUF224 cysteine-rich region domain protein. (251 aa)
NH8B_3379Homoserine dehydrogenase; K00003. (436 aa)
gpsANAD(P)H-dependent glycerol-3-phosphate dehydrogenase; K00057; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (334 aa)
NH8B_3486Glycerate dehydrogenase; K00018; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
NH8B_3539dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (303 aa)
fclGDP-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (325 aa)
NH8B_3694Nucleotide sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (427 aa)
NH8B_0252Hydroxypyruvate reductase; K00050. (420 aa)
NH8B_0220Short-chain dehydrogenase/reductase SDR; K00019; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (257 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (490 aa)
lcdH3-hydroxyacyl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. (329 aa)
NH8B_0020Malate dehydrogenase; K00029. (553 aa)
NH8B_3755Homoserine dehydrogenase; K00003. (356 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
NH8B_4089D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (332 aa)
Your Current Organism:
Pseudogulbenkiania sp. NH8B
NCBI taxonomy Id: 748280
Other names: P. sp. NH8B
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