(19 nodes) Tyrosine metabolism network (Pseudogulbenkiania sp. NH8B)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NH8B_0311	5-carboxymethyl-2-hydroxymuconate isomerase; K01826. (120 aa)
	NH8B_0449	Succinic semialdehyde dehydrogenase; K00135; Belongs to the aldehyde dehydrogenase family. (486 aa)
	NH8B_0638	4-hydroxyphenylpyruvate dioxygenase; K00457. (360 aa)
	NH8B_0639	Homogentisate 1,2-dioxygenase; K00451. (376 aa)
	NH8B_0640	Fumarylacetoacetate (FAA) hydrolase. (327 aa)
	NH8B_1101	malate/L-lactate dehydrogenase; K00016; Belongs to the LDH2/MDH2 oxidoreductase family. (358 aa)
	NH8B_1367	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase. (372 aa)
	NH8B_1478	Aromatic-amino-acid transaminase; K00832. (402 aa)
	NH8B_1487	Fumarylacetoacetate (FAA) hydrolase family protein. (217 aa)
	NH8B_2045	Fumarylacetoacetate (FAA) hydrolase. (234 aa)
	NH8B_2046	Maleylacetoacetate isomerase; K01801. (218 aa)
	NH8B_2048	Gentisate 1,2-dioxygenase; K00450. (347 aa)
	NH8B_2501	4-hydroxyphenylpyruvate dioxygenase; K00457. (645 aa)
	NH8B_2536	4-hydroxyphenylpyruvate dioxygenase; K00457. (284 aa)
	NH8B_2538	Succinic semialdehyde dehydrogenase; K00135; Belongs to the aldehyde dehydrogenase family. (483 aa)
	NH8B_2658	Aromatic-amino-acid transaminase; K00832. (402 aa)
	hisC	Histidinol-phosphate aminotransferase; K00817; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (352 aa)
	hisC-2	Histidinol-phosphate aminotransferase; K00817; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa)
	NH8B_4017	Histidinol-phosphate aminotransferase; K00817. (365 aa)

Your Current Organism:

Pseudogulbenkiania sp. NH8B

NCBI taxonomy Id: 748280
Other names: P. sp. NH8B

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NH8B_0449	NH8B_2538	NH8B_0449	NH8B_2538	Succinic semialdehyde dehydrogenase; K00135; Belongs to the aldehyde dehydrogenase family.	Succinic semialdehyde dehydrogenase; K00135; Belongs to the aldehyde dehydrogenase family.	0.901
NH8B_0638	NH8B_0639	NH8B_0638	NH8B_0639	4-hydroxyphenylpyruvate dioxygenase; K00457.	Homogentisate 1,2-dioxygenase; K00451.	0.998
NH8B_0638	NH8B_0640	NH8B_0638	NH8B_0640	4-hydroxyphenylpyruvate dioxygenase; K00457.	Fumarylacetoacetate (FAA) hydrolase.	0.905
NH8B_0638	NH8B_1101	NH8B_0638	NH8B_1101	4-hydroxyphenylpyruvate dioxygenase; K00457.	malate/L-lactate dehydrogenase; K00016; Belongs to the LDH2/MDH2 oxidoreductase family.	0.900
NH8B_0638	NH8B_1478	NH8B_0638	NH8B_1478	4-hydroxyphenylpyruvate dioxygenase; K00457.	Aromatic-amino-acid transaminase; K00832.	0.945
NH8B_0638	NH8B_2046	NH8B_0638	NH8B_2046	4-hydroxyphenylpyruvate dioxygenase; K00457.	Maleylacetoacetate isomerase; K01801.	0.849
NH8B_0638	NH8B_2501	NH8B_0638	NH8B_2501	4-hydroxyphenylpyruvate dioxygenase; K00457.	4-hydroxyphenylpyruvate dioxygenase; K00457.	0.920
NH8B_0638	NH8B_2536	NH8B_0638	NH8B_2536	4-hydroxyphenylpyruvate dioxygenase; K00457.	4-hydroxyphenylpyruvate dioxygenase; K00457.	0.915
NH8B_0638	NH8B_2658	NH8B_0638	NH8B_2658	4-hydroxyphenylpyruvate dioxygenase; K00457.	Aromatic-amino-acid transaminase; K00832.	0.945
NH8B_0638	NH8B_4017	NH8B_0638	NH8B_4017	4-hydroxyphenylpyruvate dioxygenase; K00457.	Histidinol-phosphate aminotransferase; K00817.	0.905
NH8B_0638	hisC	NH8B_0638	NH8B_3762	4-hydroxyphenylpyruvate dioxygenase; K00457.	Histidinol-phosphate aminotransferase; K00817; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.905
NH8B_0638	hisC-2	NH8B_0638	NH8B_3832	4-hydroxyphenylpyruvate dioxygenase; K00457.	Histidinol-phosphate aminotransferase; K00817; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.905
NH8B_0639	NH8B_0638	NH8B_0639	NH8B_0638	Homogentisate 1,2-dioxygenase; K00451.	4-hydroxyphenylpyruvate dioxygenase; K00457.	0.998
NH8B_0639	NH8B_0640	NH8B_0639	NH8B_0640	Homogentisate 1,2-dioxygenase; K00451.	Fumarylacetoacetate (FAA) hydrolase.	0.968
NH8B_0639	NH8B_1478	NH8B_0639	NH8B_1478	Homogentisate 1,2-dioxygenase; K00451.	Aromatic-amino-acid transaminase; K00832.	0.444
NH8B_0639	NH8B_1487	NH8B_0639	NH8B_1487	Homogentisate 1,2-dioxygenase; K00451.	Fumarylacetoacetate (FAA) hydrolase family protein.	0.821
NH8B_0639	NH8B_2045	NH8B_0639	NH8B_2045	Homogentisate 1,2-dioxygenase; K00451.	Fumarylacetoacetate (FAA) hydrolase.	0.821
NH8B_0639	NH8B_2046	NH8B_0639	NH8B_2046	Homogentisate 1,2-dioxygenase; K00451.	Maleylacetoacetate isomerase; K01801.	0.685
NH8B_0639	NH8B_2501	NH8B_0639	NH8B_2501	Homogentisate 1,2-dioxygenase; K00451.	4-hydroxyphenylpyruvate dioxygenase; K00457.	0.992
NH8B_0639	NH8B_2536	NH8B_0639	NH8B_2536	Homogentisate 1,2-dioxygenase; K00451.	4-hydroxyphenylpyruvate dioxygenase; K00457.	0.995