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| | NH8B_0054 | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1242 aa) |
| | NH8B_0055 | Cystathionine gamma-lyase; K01758. (380 aa) |
| | NH8B_0056 | Cystathionine beta-synthase; K01697. (452 aa) |
| | argH | Argininosuccinate lyase; K01755. (460 aa) |
| | NH8B_0196 | Threonine aldolase; K01620. (342 aa) |
| | glnA | Glutamate--putrescine ligase; K01915; Belongs to the glutamine synthetase family. (449 aa) |
| | NH8B_0207 | Serine O-acetyltransferase; K00640. (260 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa) |
| | NH8B_0250 | Pyruvate kinase; K00873; Belongs to the pyruvate kinase family. (478 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (372 aa) |
| | cysK | Cysteine synthase/cystathionine beta-synthase; K01738. (351 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (291 aa) |
| | glnA-2 | Glutamate--putrescine ligase; K01915; Belongs to the glutamine synthetase family. (442 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (237 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (389 aa) |
| | NH8B_0637 | Phenylalanine 4-monooxygenase; K00500. (261 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (347 aa) |
| | NH8B_0679 | Isocitrate dehydrogenase, NADP-dependent; K00031. (414 aa) |
| | NH8B_0680 | Isocitrate dehydrogenase, NADP-dependent; K00031; Belongs to the monomeric-type IDH family. (745 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (413 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate/ homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (760 aa) |
| | glnA-3 | Glutamine synthetase, type I; K01915. (472 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (273 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa) |
| | NH8B_0861 | Phosphoserine phosphatase SerB; K01079. (283 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | NH8B_1011 | Type II citrate synthase; K01647; Belongs to the citrate synthase family. (429 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa) |
| | rpiA | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (219 aa) |
| | ilvD | Dihydroxy-acid dehydratase; K01687; Belongs to the IlvD/Edd family. (618 aa) |
| | glyA | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (416 aa) |
| | NH8B_1219 | 6-phosphofructokinase; K00850. (391 aa) |
| | NH8B_1225 | Pyruvate kinase; K00873; Belongs to the pyruvate kinase family. (476 aa) |
| | glyA-2 | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa) |
| | NH8B_1343 | L-serine dehydratase 1; K01752; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa) |
| | NH8B_1411 | L-serine dehydratase 1; K01752; Belongs to the iron-sulfur dependent L-serine dehydratase family. (466 aa) |
| | glyA-3 | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa) |
| | NH8B_1478 | Aromatic-amino-acid transaminase; K00832. (402 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (212 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (354 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (370 aa) |
| | NH8B_1495 | Aspartate-semialdehyde dehydrogenase; K00133; Belongs to the aspartate-semialdehyde dehydrogenase family. (337 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; K01817; Belongs to the TrpF family. (207 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (399 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa) |
| | NH8B_1504 | D-3-phosphoglycerate dehydrogenase; K00058; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa) |
| | ilvA | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (509 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (308 aa) |
| | NH8B_1850 | Acetolactate synthase 2 catalytic subunit; K01652; Belongs to the TPP enzyme family. (527 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (342 aa) |
| | trpG | Anthranilate synthase component II; K01658. (186 aa) |
| | argD | Bifunctional N-succinyldiaminopimelate-aminotransferase/ acetylornithine transaminase protein; K00840; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (413 aa) |
| | NH8B_2214 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1145 aa) |
| | glyA-4 | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa) |
| | pheA1 | Chorismate mutase/prephenate dehydratase; K04093 K04518. (357 aa) |
| | NH8B_2237 | 3-deoxy-7-phosphoheptulonate synthase; K03856. (338 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (276 aa) |
| | glnA-4 | Glutamine synthetase, catalytic domain; K01915; Belongs to the glutamine synthetase family. (444 aa) |
| | NH8B_2360 | Asparagine synthase (glutamine-hydrolyzing); K01953. (624 aa) |
| | acnB | Aconitate hydratase 2; K01682; Belongs to the aconitase/IPM isomerase family. (861 aa) |
| | acnA-2 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (935 aa) |
| | argE | Acetylornithine deacetylase ArgE; K01438. (394 aa) |
| | NH8B_2442 | Phosphoglycerate mutase; K01834. (215 aa) |
| | NH8B_2448 | Ribose-phosphate pyrophosphokinase; K00948; Belongs to the ribose-phosphate pyrophosphokinase family. (300 aa) |
| | NH8B_2474 | Dihydrodipicolinate synthase; K01714; Belongs to the DapA family. (300 aa) |
| | glyA-5 | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa) |
| | NH8B_2503 | Shikimate dehydrogenase substrate binding domain protein; K00014. (277 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (151 aa) |
| | NH8B_2506 | D-3-phosphoglycerate dehydrogenase; K00058; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (338 aa) |
| | NH8B_2532 | Shikimate dehydrogenase substrate binding domain protein; K00014. (292 aa) |
| | NH8B_2579 | Ribulose-phosphate 3-epimerase; K01783; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (487 aa) |
| | argG | Argininosuccinate synthase; K01940; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa) |
| | NH8B_2585 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (307 aa) |
| | trpC | Indole-3-glycerol-phosphate synthase; K01609; Belongs to the TrpC family. (264 aa) |
| | NH8B_2658 | Aromatic-amino-acid transaminase; K00832. (402 aa) |
| | NH8B_2710 | Transketolase central region; K00615. (332 aa) |
| | NH8B_2711 | Transketolase domain protein; K00615. (284 aa) |
| | NH8B_2751 | Glutamate--ammonia ligase; K01915; Belongs to the glutamine synthetase family. (445 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (375 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (266 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (383 aa) |
| | cysK-2 | Cysteine synthase A; K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa) |
| | cysM | Cysteine synthase B; K12339; Belongs to the cysteine synthase/cystathionine beta- synthase family. (298 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (429 aa) |
| | NH8B_3231 | Prephenate dehydrogenase; K00210. (294 aa) |
| | trpE-2 | Anthranilate synthase component I; K01657. (431 aa) |
| | gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (506 aa) |
| | argA | Amino-acid N-acetyltransferase; K00619; Belongs to the acetyltransferase family. ArgA subfamily. (436 aa) |
| | NH8B_3369 | Aspartate kinase; K00928; Belongs to the aspartokinase family. (410 aa) |
| | NH8B_3378 | Threonine synthase; K01733. (468 aa) |
| | NH8B_3379 | Homoserine dehydrogenase; K00003. (436 aa) |
| | NH8B_3380 | Aminotransferase class I and II. (435 aa) |
| | aroQ-2 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa) |
| | gltD | Glutamate synthase subunit beta; K00266. (471 aa) |
| | gltB | Glutamate synthase subunit alpha; K00265. (1482 aa) |
| | NH8B_3570 | Cystathionine gamma-synthase; K01739. (380 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (327 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (182 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa) |
| | metXS | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (380 aa) |
| | thrB | Homoserine kinase; K02204; Belongs to the pseudomonas-type ThrB family. (312 aa) |
| | NH8B_3755 | Homoserine dehydrogenase; K00003. (356 aa) |
| | hisC | Histidinol-phosphate aminotransferase; K00817; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (352 aa) |
| | hisE | phosphoribosyl-ATP diphosphatase; K01523. (108 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (128 aa) |
| | hisF | Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (255 aa) |
| | hisA | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; K01814. (246 aa) |
| | hisH | Imidazoleglycerol-phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (213 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; K01693. (199 aa) |
| | hisC-2 | Histidinol-phosphate aminotransferase; K00817; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (213 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (597 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa) |
| | NH8B_3852 | Acetolactate synthase, small subunit; K01653. (163 aa) |
| | NH8B_3853 | Acetolactate synthase, large subunit, biosynthetic type; K01652. (586 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (352 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (405 aa) |
| | NH8B_3945 | Aminotransferase class I and II; K00821, succinyldiaminopimelate transaminase. (407 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; K00674; Belongs to the transferase hexapeptide repeat family. (285 aa) |
| | NH8B_3984 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (662 aa) |
| | gapA | Glyceraldehyde-3-phosphate dehydrogenase, type I; K00134; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa) |
| | pgk | Phosphoglycerate kinase; K00927; Belongs to the phosphoglycerate kinase family. (392 aa) |
| | fbaA | Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | NH8B_3999 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (377 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (267 aa) |
| | NH8B_4017 | Histidinol-phosphate aminotransferase; K00817. (365 aa) |
| | serC-2 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa) |
