(75 nodes) Protein kinase complex network (Anopheles sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ZHAS_00014450	AGAP011110-PA-like protein. (638 aa)
	ZHAS_00013329	AGAP003980-PA-like protein; Belongs to the STXBP/unc-18/SEC1 family. (574 aa)
	ZHAS_00013183	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa)
	ZHAS_00013002	PB1 domain-containing protein. (102 aa)
	ZHAS_00001517	PID domain-containing protein. (562 aa)
	ZHAS_00009934	AGAP008630-PA-like protein. (576 aa)
	ZHAS_00010145	AGAP010118-PA-like protein. (242 aa)
	ZHAS_00010253	AGAP000869-PA-like protein. (1909 aa)
	ZHAS_00010746	AGAP008873-PA-like protein. (1262 aa)
	ZHAS_00002367	AGAP001446-PA-like protein. (538 aa)
	ZHAS_00002763	AGAP001446-PB-like protein. (793 aa)
	ZHAS_00003819	AGAP007669-PA-like protein. (189 aa)
	ZHAS_00004342	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (613 aa)
	ZHAS_00004492	AMPKBI domain-containing protein. (238 aa)
	ZHAS_00019383	AGAP010623-PA-like protein. (552 aa)
	ZHAS_00004887	Cyclin-dependent kinase 5 activator. (359 aa)
	ZHAS_00005231	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (496 aa)
	ZHAS_00005555	Uncharacterized protein. (381 aa)
	ZHAS_00005964	AGAP011295-PA-like protein. (490 aa)
	ZHAS_00006119	AMPKBI domain-containing protein. (289 aa)
	ZHAS_00006424	AGAP008417-PA-like protein; Belongs to the cyclin family. (333 aa)
	ZHAS_00018334	Uncharacterized protein. (442 aa)
	ZHAS_00018011	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (148 aa)
	ZHAS_00017995	Tyrosine-protein kinase receptor. (1596 aa)
	ZHAS_00017990	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (503 aa)
	ZHAS_00017811	AGAP012299-PA-like protein. (123 aa)
	ZHAS_00017809	AGAP012299-PA-like protein. (60 aa)
	ZHAS_00021398	Non-specific serine/threonine protein kinase. (557 aa)
	ZHAS_00020741	AGAP008969-PA-like protein; Belongs to the cyclin family. (362 aa)
	ZHAS_00020195	AGAP006436-PA-like protein. (1254 aa)
	ZHAS_00020194	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1033 aa)
	ZHAS_00017808	AGAP012299-PA-like protein; Belongs to the cyclin family. (224 aa)
	ZHAS_00006659	AGAP009166-PA-like protein. (815 aa)
	ZHAS_00017298	AGAP009262-PA-like protein. (1063 aa)
	ZHAS_00018824	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (970 aa)
	ZHAS_00018469	Cdk5; Belongs to the protein kinase superfamily. (289 aa)
	ZHAS_00018335	RanBP2-type domain-containing protein. (388 aa)
	ZHAS_00001446	AGAP007823-PA-like protein. (825 aa)
	ZHAS_00001447	AGAP007823-PA-like protein. (440 aa)
	ZHAS_00017261	AGAP008627-PA-like protein. (502 aa)
	ZHAS_00017194	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (314 aa)
	ZHAS_00017183	Uncharacterized protein. (258 aa)
	ZHAS_00007140	Serine/threonine-protein kinase NIM1. (711 aa)
	ZHAS_00019746	Serpin 7; Belongs to the serpin family. (387 aa)
	ZHAS_00007339	AGAP009459-PA-like protein; Belongs to the protein kinase superfamily. (298 aa)
	ZHAS_00009055	AGAP008541-PA-like protein; Belongs to the protein kinase superfamily. (401 aa)
	ZHAS_00009116	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (77 aa)
	ZHAS_00009201	AGAP005252-PA-like protein. (469 aa)
	ZHAS_00009671	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1234 aa)
	ZHAS_00009526	AGAP000747-PB-like protein. (1499 aa)
	ZHAS_00009931	N-acetyltransferase domain-containing protein. (284 aa)
	ZHAS_00016432	AGAP004962-PA-like protein; Belongs to the cyclin family. (492 aa)
	ZHAS_00016431	AGAP004963-PA-like protein; Belongs to the cyclin family. (492 aa)
	ZHAS_00016315	AGAP005715-PA-like protein. (60 aa)
	ZHAS_00016314	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (211 aa)
	ZHAS_00016312	Uncharacterized protein. (311 aa)
	ZHAS_00016358	AGAP005817-PA-like protein; Belongs to the protein kinase superfamily. (301 aa)
	ZHAS_00016251	AGAP008002-PA-like protein; Belongs to the cyclin family. (376 aa)
	ZHAS_00014982	AGAP004780-PA-like protein. (502 aa)
	ZHAS_00014981	AGAP004780-PA-like protein. (1523 aa)
	ZHAS_00014798	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (488 aa)
	ZHAS_00014021	AGAP002647-PA-like protein; Belongs to the protein kinase superfamily. (416 aa)
	ZHAS_00014305	WW domain-containing protein. (490 aa)
	ZHAS_00014243	AGAP004594-PA-like protein; Belongs to the protein kinase superfamily. (292 aa)
	ZHAS_00013049	Uncharacterized protein; Belongs to the protein kinase superfamily. (464 aa)
	ZHAS_00012838	Uncharacterized protein. (58 aa)
	ZHAS_00012124	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2269 aa)
	ZHAS_00011534	AGAP013332-PA-like protein. (1143 aa)
	ZHAS_00011033	Uncharacterized protein. (1009 aa)
	ZHAS_00014022	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (340 aa)
	ZHAS_00022385	TPR_REGION domain-containing protein. (184 aa)
	ZHAS_00021681	Uncharacterized protein. (321 aa)
	ZHAS_00021623	AGAP006678-PA-like protein; Belongs to the cyclin family. (1302 aa)
	ZHAS_00021457	AGAP003616-PA-like protein. (2278 aa)
	ZHAS_00021433	AGAP003873-PA-like protein. (1793 aa)

Your Current Organism:

Anopheles sinensis

NCBI taxonomy Id: 74873
Other names: A. sinensis, Anopheles (Anopheles) sinensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ZHAS_00001446	ZHAS_00001447	A0A084VBC8	A0A084VBC9	AGAP007823-PA-like protein.	AGAP007823-PA-like protein.	0.656
ZHAS_00001446	ZHAS_00017183	A0A084VBC8	A0A084WFU2	AGAP007823-PA-like protein.	Uncharacterized protein.	0.404
ZHAS_00001446	ZHAS_00017194	A0A084VBC8	A0A084WFU3	AGAP007823-PA-like protein.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.404
ZHAS_00001446	ZHAS_00017990	A0A084VBC8	A0A084WIB0	AGAP007823-PA-like protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.620
ZHAS_00001447	ZHAS_00001446	A0A084VBC9	A0A084VBC8	AGAP007823-PA-like protein.	AGAP007823-PA-like protein.	0.656
ZHAS_00001447	ZHAS_00017183	A0A084VBC9	A0A084WFU2	AGAP007823-PA-like protein.	Uncharacterized protein.	0.404
ZHAS_00001447	ZHAS_00017194	A0A084VBC9	A0A084WFU3	AGAP007823-PA-like protein.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.404
ZHAS_00001447	ZHAS_00017990	A0A084VBC9	A0A084WIB0	AGAP007823-PA-like protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.620
ZHAS_00001517	ZHAS_00006424	A0A084VBE7	A0A084VMA4	PID domain-containing protein.	AGAP008417-PA-like protein; Belongs to the cyclin family.	0.998
ZHAS_00001517	ZHAS_00009201	A0A084VBE7	A0A084VUF3	PID domain-containing protein.	AGAP005252-PA-like protein.	0.571
ZHAS_00001517	ZHAS_00012838	A0A084VBE7	A0A084W3Y0	PID domain-containing protein.	Uncharacterized protein.	0.995
ZHAS_00001517	ZHAS_00014022	A0A084VBE7	A0A084W754	PID domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.982
ZHAS_00001517	ZHAS_00014243	A0A084VBE7	A0A084W7R6	PID domain-containing protein.	AGAP004594-PA-like protein; Belongs to the protein kinase superfamily.	0.974
ZHAS_00001517	ZHAS_00014450	A0A084VBE7	A0A084W8B4	PID domain-containing protein.	AGAP011110-PA-like protein.	0.999
ZHAS_00001517	ZHAS_00014798	A0A084VBE7	A0A084W999	PID domain-containing protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.999
ZHAS_00001517	ZHAS_00014981	A0A084VBE7	A0A084W9S2	PID domain-containing protein.	AGAP004780-PA-like protein.	0.596
ZHAS_00001517	ZHAS_00014982	A0A084VBE7	A0A084W9S3	PID domain-containing protein.	AGAP004780-PA-like protein.	0.596
ZHAS_00001517	ZHAS_00016251	A0A084VBE7	A0A084WD88	PID domain-containing protein.	AGAP008002-PA-like protein; Belongs to the cyclin family.	0.777
ZHAS_00001517	ZHAS_00017183	A0A084VBE7	A0A084WFU2	PID domain-containing protein.	Uncharacterized protein.	0.973
ZHAS_00001517	ZHAS_00017194	A0A084VBE7	A0A084WFU3	PID domain-containing protein.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.982