node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADV45551.1 | ADV45565.1 | Nitsa_0280 | Nitsa_0294 | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: sun:SUN_1998 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR010957: IPR020822: IPR001086: IPR002912: IPR 008242: IPR002701; KEGG: sun:SUN_2057 chorismate mutase/prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. | 0.968 |
ADV45551.1 | ADV46577.1 | Nitsa_0280 | Nitsa_1326 | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: sun:SUN_1998 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. | Chorismate mutase, type II; InterPro IPR020822: IPR002701; KEGG: sun:SUN_1870 chorismate mutase; PFAM: Chorismate mutase, type II; SPTR: Chorismate mutase; PFAM: Chorismate mutase type II. | 0.658 |
ADV45551.1 | ADV46738.1 | Nitsa_0280 | Nitsa_1490 | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: sun:SUN_1998 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR001176: IPR004838; KEGG: sun:SUN_1362 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase; manually curated; PFAM: Aminotransferase class I and II. | 0.908 |
ADV45551.1 | aroA | Nitsa_0280 | Nitsa_0329 | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: sun:SUN_1998 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.984 |
ADV45551.1 | aroB | Nitsa_0280 | Nitsa_1289 | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: sun:SUN_1998 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.808 |
ADV45551.1 | aroC | Nitsa_0280 | Nitsa_2070 | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: sun:SUN_1998 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.804 |
ADV45551.1 | aroE | Nitsa_0280 | Nitsa_0690 | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: sun:SUN_1998 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.490 |
ADV45551.1 | aroK | Nitsa_0280 | Nitsa_1954 | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: sun:SUN_1998 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.726 |
ADV45565.1 | ADV45551.1 | Nitsa_0294 | Nitsa_0280 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR010957: IPR020822: IPR001086: IPR002912: IPR 008242: IPR002701; KEGG: sun:SUN_2057 chorismate mutase/prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: sun:SUN_1998 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. | 0.968 |
ADV45565.1 | ADV45802.1 | Nitsa_0294 | Nitsa_0532 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR010957: IPR020822: IPR001086: IPR002912: IPR 008242: IPR002701; KEGG: sun:SUN_2057 chorismate mutase/prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. | COGs: COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002480; KEGG: sun:SUN_0466 3-deoxy-7-phosphoheptulonate synthase, class II; PFAM: DAHP synthetase class II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase, class II; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Class-II DAHP synthetase family; TIGRFAM: 3-deoxy-7-phosphoheptulonate synthase, class II. | 0.855 |
ADV45565.1 | ADV46738.1 | Nitsa_0294 | Nitsa_1490 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR010957: IPR020822: IPR001086: IPR002912: IPR 008242: IPR002701; KEGG: sun:SUN_2057 chorismate mutase/prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR001176: IPR004838; KEGG: sun:SUN_1362 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase; manually curated; PFAM: Aminotransferase class I and II. | 0.938 |
ADV45565.1 | aroA | Nitsa_0294 | Nitsa_0329 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR010957: IPR020822: IPR001086: IPR002912: IPR 008242: IPR002701; KEGG: sun:SUN_2057 chorismate mutase/prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.879 |
ADV45565.1 | aroB | Nitsa_0294 | Nitsa_1289 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR010957: IPR020822: IPR001086: IPR002912: IPR 008242: IPR002701; KEGG: sun:SUN_2057 chorismate mutase/prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.623 |
ADV45565.1 | aroC | Nitsa_0294 | Nitsa_2070 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR010957: IPR020822: IPR001086: IPR002912: IPR 008242: IPR002701; KEGG: sun:SUN_2057 chorismate mutase/prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.982 |
ADV45565.1 | aroE | Nitsa_0294 | Nitsa_0690 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR010957: IPR020822: IPR001086: IPR002912: IPR 008242: IPR002701; KEGG: sun:SUN_2057 chorismate mutase/prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.652 |
ADV45565.1 | aroK | Nitsa_0294 | Nitsa_1954 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR010957: IPR020822: IPR001086: IPR002912: IPR 008242: IPR002701; KEGG: sun:SUN_2057 chorismate mutase/prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.697 |
ADV45565.1 | katG | Nitsa_0294 | Nitsa_0184 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR010957: IPR020822: IPR001086: IPR002912: IPR 008242: IPR002701; KEGG: sun:SUN_2057 chorismate mutase/prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. | Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.800 |
ADV45802.1 | ADV45565.1 | Nitsa_0532 | Nitsa_0294 | COGs: COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002480; KEGG: sun:SUN_0466 3-deoxy-7-phosphoheptulonate synthase, class II; PFAM: DAHP synthetase class II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase, class II; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Class-II DAHP synthetase family; TIGRFAM: 3-deoxy-7-phosphoheptulonate synthase, class II. | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR010957: IPR020822: IPR001086: IPR002912: IPR 008242: IPR002701; KEGG: sun:SUN_2057 chorismate mutase/prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. | 0.855 |
ADV45802.1 | ADV46577.1 | Nitsa_0532 | Nitsa_1326 | COGs: COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002480; KEGG: sun:SUN_0466 3-deoxy-7-phosphoheptulonate synthase, class II; PFAM: DAHP synthetase class II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase, class II; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Class-II DAHP synthetase family; TIGRFAM: 3-deoxy-7-phosphoheptulonate synthase, class II. | Chorismate mutase, type II; InterPro IPR020822: IPR002701; KEGG: sun:SUN_1870 chorismate mutase; PFAM: Chorismate mutase, type II; SPTR: Chorismate mutase; PFAM: Chorismate mutase type II. | 0.778 |
ADV45802.1 | aroB | Nitsa_0532 | Nitsa_1289 | COGs: COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002480; KEGG: sun:SUN_0466 3-deoxy-7-phosphoheptulonate synthase, class II; PFAM: DAHP synthetase class II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase, class II; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Class-II DAHP synthetase family; TIGRFAM: 3-deoxy-7-phosphoheptulonate synthase, class II. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.924 |