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coaE coaE gmk gmk pgk pgk tpiA tpiA eno eno ADV45525.1 ADV45525.1 ndk ndk selD selD ADV45584.1 ADV45584.1 lpxK lpxK argB argB ADV45678.1 ADV45678.1 ADV45689.1 ADV45689.1 ADV45696.1 ADV45696.1 proB proB ADV45755.1 ADV45755.1 gpmI gpmI ADV45761.1 ADV45761.1 ADV45763.1 ADV45763.1 ADV45797.1 ADV45797.1 ADV45803.1 ADV45803.1 ADV45906.1 ADV45906.1 ADV45948.1 ADV45948.1 ADV46003.1 ADV46003.1 ADV46006.1 ADV46006.1 ackA ackA ADV46034.1 ADV46034.1 ADV46082.1 ADV46082.1 pyrH pyrH adk adk tmk tmk ADV46220.1 ADV46220.1 ADV46226.1 ADV46226.1 ADV46228.1 ADV46228.1 eno-2 eno-2 ADV46246.1 ADV46246.1 gpmA gpmA ADV46265.1 ADV46265.1 ADV46267.1 ADV46267.1 ADV46324.1 ADV46324.1 thiL thiL nadK nadK ADV46487.1 ADV46487.1 prs prs ADV46561.1 ADV46561.1 ADV46597.1 ADV46597.1 ispE ispE ADV46616.1 ADV46616.1 ADV46612.1 ADV46612.1 ADV47309.1 ADV47309.1 ppk ppk aroK aroK ADV47157.1 ADV47157.1 ADV47154.1 ADV47154.1 thrB thrB ADV46978.1 ADV46978.1 ADV46953.1 ADV46953.1 ADV46884.1 ADV46884.1 ADV46879.1 ADV46879.1 ADV46736.1 ADV46736.1 ADV46731.1 ADV46731.1 hldE hldE
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa)
pgkCOGs: COG0126 3-phosphoglycerate kinase; InterPro IPR015911: IPR001576; KEGG: sun:SUN_2203 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (402 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (235 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (423 aa)
ADV45525.1COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660: IPR003661: IPR003594: IPR005467; KEGG: sun:SUN_2093 two-component sensor histidine kinase; PFAM: histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: Two-component sensor histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (407 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa)
selDSelenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. (344 aa)
ADV45584.1Protein of unknown function DUF344; COGs: COG2326 conserved hypothetical protein; InterPro IPR016898: IPR005660; KEGG: sun:SUN_1807 hypothetical protein; PFAM: protein of unknown function DUF344; SPTR: Putative uncharacterized protein; PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate kinase 2, PA0141 family. (303 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (312 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (283 aa)
ADV45678.1COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR005467: IPR000014: IPR000700: IPR004358: IPR 001610: IPR003594: IPR013655; KEGG: tdn:Suden_1243 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase [...] (409 aa)
ADV45689.1Hpt domain protein; InterPro IPR008207; KEGG: sun:SUN_1903 hypothetical protein; PFAM: Hpt domain protein; SPTR: Putative uncharacterized protein; PFAM: Hpt domain. (523 aa)
ADV45696.1Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (122 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (263 aa)
ADV45755.1Diacylglycerol kinase catalytic region; COGs: COG1597 Sphingosine kinase; InterPro IPR001206: IPR005218; KEGG: vpa:VPA0693 lipid kinase; PFAM: diacylglycerol kinase catalytic region; SPTR: Probable lipid kinase yegS-like; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family; lipid kinase YegS. (301 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (499 aa)
ADV45761.1COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR004358: IPR003594; KEGG: sun:SUN_2186 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Two-component sensor histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (286 aa)
ADV45763.1COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR004358: IPR003594; KEGG: sun:SUN_2242 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Two-component sensor histidine kinase; manually curated; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (365 aa)
ADV45797.1Putative transcriptional acitvator, Baf family; COGs: COG1521 Putative transcriptional regulator protein; InterPro IPR004619; KEGG: sun:SUN_0423 pantothenate kinase; PFAM: Bvg accessory factor; SPTR: Transcriptional activator, Baf family; TIGRFAM: transcriptional activator, Baf family; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III. (206 aa)
ADV45803.1COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003660: IPR003594; KEGG: sun:SUN_0467 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SPTR: Two-component sensor histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (410 aa)
ADV45906.1COGs: COG0527 Aspartokinase; InterProIPR005260: IPR001341: IPR018042: IPR001048: IPR 002912; KEGG: sun:SUN_0456 aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (401 aa)
ADV45948.1KEGG: sun:SUN_2081 hypothetical protein; SPTR: Putative uncharacterized protein. (309 aa)
ADV46003.1KEGG: sun:SUN_2076 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Coenzyme PQQ synthesis protein D (PqqD). (90 aa)
ADV46006.1KEGG: sun:SUN_2081 hypothetical protein; SPTR: Putative uncharacterized protein. (303 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)
ADV46034.1COGs: COG3869 Arginine kinase; InterPro IPR000749; KEGG: sun:SUN_1812 arginine kinase; PFAM: ATP:guanido phosphotransferase; PRIAM: Arginine kinase; SPTR: Arginine kinase; PFAM: ATP:guanido phosphotransferase, N-terminal domain; ATP:guanido phosphotransferase, C-terminal catalytic domain; Belongs to the ATP:guanido phosphotransferase family. (344 aa)
ADV46082.1GCN5-related N-acetyltransferase; InterPro IPR000182: IPR003594; KEGG: sun:SUN_0170 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; ATP-binding region ATPase domain protein; SPTR: Putative uncharacterized protein; PFAM: Acetyltransferase (GNAT) family; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (488 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (237 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (199 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (191 aa)
ADV46220.1Protein of unknown function DUF344; COGs: COG2326 conserved hypothetical protein; InterPro IPR016898: IPR005660; KEGG: sun:SUN_1287 hypothetical protein; PFAM: protein of unknown function DUF344; SPTR: Putative uncharacterized protein; PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate kinase 2, PA0141 family. (252 aa)
ADV46226.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa)
ADV46228.1COGs: COG1830 DhnA-type fructose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: sun:SUN_1211 aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; SPTR: Fructose-bisphosphate aldolase, class I; PFAM: DeoC/LacD family aldolase. (305 aa)
eno-2Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
ADV46246.1ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: nis:NIS_0938 hypothetical protein; PFAM: ROK family protein; SPTR: Putative uncharacterized protein; PFAM: ROK family. (258 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (229 aa)
ADV46265.1COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: sun:SUN_1276 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase. (417 aa)
ADV46267.16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (319 aa)
ADV46324.1Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001638: IPR003661: IPR003594: IPR 004358; KEGG: wsu:WS0850 sensory transduction histidine kinase; PFAM: extracellular solute-binding protein family 3; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: extracellular solute-binding protein family 3; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: SENSORY TRANSDUCTION HISTIDINE KINASE; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) do [...] (1109 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (278 aa)
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (292 aa)
ADV46487.1Domain of unknown function DUF1745; COGs: COG3287 conserved hypothetical protein; InterPro IPR013702: IPR019494; KEGG: nde:NIDE0806 hypothetical protein; PFAM: domain of unknown function DUF1745; FIST C domain; SPTR: Putative uncharacterized protein; PFAM: FIST C domain; FIST N domain. (379 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa)
ADV46561.1PAS fold domain protein; InterPro IPR013767: IPR000014; KEGG: sun:SUN_1637 hypothetical protein; PFAM: PAS fold domain protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. (233 aa)
ADV46597.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550: IPR002052; KEGG: nis:NIS_0432 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosp [...] (186 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (259 aa)
ADV46616.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)
ADV46612.1COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003661: IPR003594: IPR004358: IPR005467; KEGG: ccv:CCV52592_1804 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (603 aa)
ADV47309.1Integral membrane sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: tdn:Suden_1558 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (471 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (701 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (191 aa)
ADV47157.1COGs: COG0469 Pyruvate kinase; InterPro IPR001697: IPR015793: IPR015794; KEGG: sun:SUN_0436 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (490 aa)
ADV47154.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR003661: IPR003594: IPR003660: IPR 004358; KEGG: nis:NIS_0410 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Two-component sensor histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (433 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (294 aa)
ADV46978.1Capsular exopolysaccharide family; COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR003856: IPR005702; KEGG: sun:SUN_1559 capsular polysaccharide biosynthesis protein; PFAM: lipopolysaccharide biosynthesis protein; PRIAM: Non-specific protein-tyrosine kinase; SPTR: Capsular polysaccharide biosynthesis protein; TIGRFAM: capsular exopolysaccharide family; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family. (780 aa)
ADV46953.1KEGG: sun:SUN_2081 hypothetical protein; SPTR: Putative uncharacterized protein. (322 aa)
ADV46884.1COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003594: IPR004358: IPR005467: IPR003660; KEGG: ant:Arnit_1871 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (626 aa)
ADV46879.1Riboflavin kinase; COGs: COG0196 FAD synthase; InterPro IPR015864: IPR015865; KEGG: sun:SUN_0463 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: Riboflavin kinase; FAD synthetase; SPTR: Riboflavin biosynthesis regulatory protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase. (272 aa)
ADV46736.1KEGG: sun:SUN_1844 hypothetical protein; SPTR: Putative uncharacterized protein. (272 aa)
ADV46731.1COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR004358: IPR005467; KEGG: sun:SUN_0681 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Two-component sensor histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (389 aa)
hldED-alpha,beta-D-heptose 7-phosphate 1-kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (477 aa)
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
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