STRINGSTRING
accD accD ADV46309.1 ADV46309.1 ADV46318.1 ADV46318.1 acsA acsA thiL thiL ADV46341.1 ADV46341.1 ADV46348.1 ADV46348.1 ADV46360.1 ADV46360.1 ADV46367.1 ADV46367.1 valS valS ADV46383.1 ADV46383.1 ADV46390.1 ADV46390.1 nadK nadK rlpA-2 rlpA-2 argG argG secA secA ADV46405.1 ADV46405.1 ADV46448.1 ADV46448.1 ADV46465.1 ADV46465.1 clpX clpX ADV46473.1 ADV46473.1 carB carB lepA lepA prs prs ADV46492.1 ADV46492.1 ADV46497.1 ADV46497.1 cysS cysS pckA pckA ADV46511.1 ADV46511.1 ADV46513.1 ADV46513.1 ADV46533.1 ADV46533.1 ADV46538.1 ADV46538.1 ADV46545.1 ADV46545.1 mnmE mnmE purL purL ADV46560.1 ADV46560.1 ADV46566.1 ADV46566.1 ADV46572.1 ADV46572.1 ADV46575.1 ADV46575.1 ADV46586.1 ADV46586.1 ADV46587.1 ADV46587.1 metG metG ADV46591.1 ADV46591.1 mnmA mnmA ADV46596.1 ADV46596.1 ADV46597.1 ADV46597.1 ADV46624.1 ADV46624.1 ispE ispE ADV46671.1 ADV46671.1 gmhA gmhA hldE hldE ftsZ ftsZ ftsA ftsA ADV46703.1 ADV46703.1 ADV46724.1 ADV46724.1 ADV46751.1 ADV46751.1 ADV46755.1 ADV46755.1 ADV46756.1 ADV46756.1 purC purC purS purS purQ purQ queC queC ychF ychF ADV46784.1 ADV46784.1 ADV46788.1 ADV46788.1 gatA gatA ADV46819.1 ADV46819.1 alaS alaS panC panC ADV46832.1 ADV46832.1 ADV46845.1 ADV46845.1 ADV46879.1 ADV46879.1 rho rho gatC gatC ADV46900.1 ADV46900.1 lysS lysS ADV46905.1 ADV46905.1 ADV46906.1 ADV46906.1 ADV46909.1 ADV46909.1 ADV46911.1 ADV46911.1 ADV46914.1 ADV46914.1 ADV46926.1 ADV46926.1 ftsH ftsH ADV46951.1 ADV46951.1 ADV46953.1 ADV46953.1 ADV46978.1 ADV46978.1 ADV46983.1 ADV46983.1 ADV47039.1 ADV47039.1 ADV47072.1 ADV47072.1 ADV47079.1 ADV47079.1 ADV47084.1 ADV47084.1 moaA moaA ADV47122.1 ADV47122.1 ADV47130.1 ADV47130.1 groS groS groL groL infB infB thrB thrB ADV47157.1 ADV47157.1 ribA ribA ADV47173.1 ADV47173.1 ddl ddl carA carA purA purA aroK aroK fusA fusA rpoB rpoB tuf tuf gyrB gyrB gltX gltX ADV47240.1 ADV47240.1 ADV47242.1 ADV47242.1 mutS2 mutS2 ADV47249.1 ADV47249.1 ADV47268.1 ADV47268.1 priA priA uvrB uvrB ppk ppk tilS tilS ADV47299.1 ADV47299.1 ADV47316.1 ADV47316.1 glnS glnS ADV47339.1 ADV47339.1 thrS thrS purM purM ADV47357.1 ADV47357.1 dnaA dnaA pyrG pyrG folE folE ADV45286.1 ADV45286.1 mobA mobA ADV45297.1 ADV45297.1 coaE coaE ADV45312.1 ADV45312.1 ADV45318.1 ADV45318.1 ADV45329.1 ADV45329.1 ADV45332.1 ADV45332.1 ADV45341.1 ADV45341.1 ADV45357.1 ADV45357.1 ADV45368.1 ADV45368.1 murE murE ADV45412.1 ADV45412.1 miaA miaA gmk gmk argS argS nadD nadD pgk pgk recA recA ADV45494.1 ADV45494.1 purT purT nnrE nnrE ruvB ruvB ADV45533.1 ADV45533.1 dnaX dnaX leuS leuS ADV45540.1 ADV45540.1 mfd mfd ADV45543.1 ADV45543.1 bioD bioD ADV45557.1 ADV45557.1 ADV45560.1 ADV45560.1 metK metK ndk ndk selD selD ADV45586.1 ADV45586.1 pheS pheS pheT pheT sucC sucC serS serS radA radA ftsY ftsY ADV45656.1 ADV45656.1 lpxK lpxK argB argB ADV45670.1 ADV45670.1 lon lon guaA guaA ADV45696.1 ADV45696.1 obg obg proB proB ADV45710.1 ADV45710.1 atpA atpA atpG atpG atpD atpD atpC atpC htpG htpG purD purD ADV45729.1 ADV45729.1 dnaJ dnaJ dnaK dnaK ADV45755.1 ADV45755.1 ADV45756.1 ADV45756.1 ADV45772.1 ADV45772.1 ADV45789.1 ADV45789.1 accA accA ADV45797.1 ADV45797.1 hisG hisG ADV45812.1 ADV45812.1 glmS glmS ADV45844.1 ADV45844.1 hisI hisI ADV45855.1 ADV45855.1 ADV45892.1 ADV45892.1 ileS ileS ADV45899.1 ADV45899.1 ADV45906.1 ADV45906.1 ADV45914.1 ADV45914.1 trpS trpS der der ADV45924.1 ADV45924.1 ADV45948.1 ADV45948.1 ADV45954.1 ADV45954.1 glyQ glyQ ffh ffh gatB gatB glyS glyS era era ADV45986.1 ADV45986.1 ADV46003.1 ADV46003.1 ADV46006.1 ADV46006.1 ADV46008.1 ADV46008.1 ruvA ruvA ackA ackA ADV46034.1 ADV46034.1 ADV46041.1 ADV46041.1 ADV46046.1 ADV46046.1 ADV46075.1 ADV46075.1 ADV46076.1 ADV46076.1 ADV46082.1 ADV46082.1 ADV46091.1 ADV46091.1 ADV46093.1 ADV46093.1 ADV46117.1 ADV46117.1 ADV46118.1 ADV46118.1 pyrH pyrH tyrS tyrS ADV46145.1 ADV46145.1 proS proS adk adk aspS aspS upp upp nadE nadE ADV46191.1 ADV46191.1 rlpA rlpA ADV46202.1 ADV46202.1 engB engB hisS hisS tmk tmk coaD coaD ADV46217.1 ADV46217.1 ADV46219.1 ADV46219.1 ADV46226.1 ADV46226.1 ADV46239.1 ADV46239.1 ADV46240.1 ADV46240.1 ADV46246.1 ADV46246.1 ADV46265.1 ADV46265.1 ADV46267.1 ADV46267.1 gyrA gyrA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (280 aa)
ADV46309.1CRISPR-associated helicase, Cas3 family; COGs: COG1203 helicase; InterProIPR006474: IPR014021: IPR001650: IPR011545: IPR 014001; KEGG: cco:CCC13826_1422 CRISPR-associated helicase Cas3 domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: CRISPR-associated helicase Cas3 domain protein; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: Type III restriction enzyme, res subunit; TIGRFAM: CRISPR-associated helicase Cas3. (725 aa)
ADV46318.1Von Willebrand factor type A; InterPro IPR002035; KEGG: sun:SUN_2020 hypothetical protein; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: Putative uncharacterized protein; PFAM: von Willebrand factor type A domain. (398 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (653 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (278 aa)
ADV46341.1UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016: IPR014017: IPR000212; KEGG: sun:SUN_1187 ATP-dependent DNA helicase UvrD; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase, UvrD/REP family; PFAM: UvrD/REP helicase. (685 aa)
ADV46348.1COGs: COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; InterPro IPR004435: IPR003593; KEGG: nis:NIS_0797 molybdopterin-guanine dinucleotide biosynthesis protein B; SMART: AAA ATPase; SPTR: Molybdopterin-guanine dinucleotide biosynthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: Molybdopterin guanine dinucleotide synthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB. (168 aa)
ADV46360.1VanZ family protein; InterPro IPR006976; KEGG: alv:Alvin_2321 hypothetical protein; PFAM: VanZ family protein; SPTR: Putative uncharacterized protein; PFAM: VanZ like family. (133 aa)
ADV46367.1ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439: IPR003593; KEGG: nis:NIS_0866 oligopeptide ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Oligopeptide ABC transporter, ATP-binding protein; PFAM: ABC transporter. (205 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (877 aa)
ADV46383.1KEGG: nis:NIS_0953 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Dynamin family. (462 aa)
ADV46390.1SMC domain protein; May be involved in recombinational repair of damaged DNA. (515 aa)
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (292 aa)
rlpA-2Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (125 aa)
argGCOGs: COG0137 Argininosuccinate synthase; InterPro IPR001518: IPR018223; KEGG: sun:SUN_1685 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (443 aa)
secAProtein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (878 aa)
ADV46405.1KEGG: sun:SUN_1635 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Archaea bacterial proteins of unknown function. (307 aa)
ADV46448.1Hypothetical protein; KEGG: ccv:CCV52592_0042 type II secretion system protein; SPTR: Type II secretion system protein; PFAM: KaiC. (347 aa)
ADV46465.1ABC transporter related protein; COGs: COG1127 ABC-type transport system involved in resistance to organic solvents ATPase component; InterPro IPR003439: IPR017871: IPR001020: IPR003593; KEGG: sun:SUN_1358 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter. (269 aa)
clpXSigma 54 interacting domain protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (405 aa)
ADV46473.1Rod shape-determining protein MreB; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: sun:SUN_1109 rod shape-determining protein MreB; PFAM: cell shape determining protein MreB/Mrl; SPTR: Cell shape-determining protein MreB; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family. (347 aa)
carBCOGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005481: IPR005479: IPR005480: IPR011607: IPR 005483: IPR006275: IPR011761; KEGG: sun:SUN_1107 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: Carbamoylphosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS- [...] (1089 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (604 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa)
ADV46492.1ATP-dependent helicase HrpB; COGs: COG1643 HrpA-like helicase; InterProIPR001650: IPR007502: IPR013689: IPR010225: IPR 014001: IPR016160: IPR014021; KEGG: rce:RC1_1438 ATP-dependent helicase protein, putative; PFAM: Helicase ATP-dependent domain protein; helicase domain protein; helicase-associated domain protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: ATP-dependent helicase protein, putative; TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); ATP-dependent helicase C-terminal; DEAD/DEAH box helicase; T [...] (826 aa)
ADV46497.1COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: sun:SUN_1474 hypothetical protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Putative uncharacterized protein; PFAM: Flavin reductase like domain. (199 aa)
cysSCOGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803: IPR015273: IPR002308; KEGG: sun:SUN_0820 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (470 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (527 aa)
ADV46511.1DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545: IPR001650: IPR014001: IPR000629: IPR 014021: IPR014014; KEGG: sun:SUN_1435 DEAD-box ATP dependent DNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent RNA helicase, DEAD-box family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (462 aa)
ADV46513.1ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR001140: IPR003439: IPR003593: IPR017871: IPR 017940; KEGG: sun:SUN_1437 multidrug ABC transporter, ATP-binding protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: Multidrug ABC transporter, ATP-binding protein; PFAM: ABC transporter transmembrane region; ABC transporter. (588 aa)
ADV46533.1COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453: IPR008284: IPR020817; KEGG: sun:SUN_1171 molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor biosynthesis protein B; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (177 aa)
ADV46538.1Adenosinetriphosphatase; COGs: COG0465 ATP-dependent Zn protease; InterPro IPR003959: IPR000642: IPR003593: IPR003960; KEGG: sun:SUN_1013 ATP-dependent zinc metalloproteinase; PFAM: AAA ATPase central domain protein; peptidase M41; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: ATP-dependent zinc metalloproteinase; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH; Belongs to the AAA ATPase family. (551 aa)
ADV46545.1Protein of unknown function DUF450; COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR007409: IPR006935: IPR014001: IPR014021; KEGG: nth:Nther_0797 protein of unknown function DUF450; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: DEAD/DEAH box helicase; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit. (996 aa)
mnmEtRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (446 aa)
purLPhosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (741 aa)
ADV46560.1Transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002197; KEGG: sun:SUN_1636 fis family transcriptional regulator; PFAM: helix-turn-helix Fis-type; SPTR: Transcriptional regulator, Fis family; PFAM: Bacterial regulatory protein, Fis family. (246 aa)
ADV46566.1Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain protein; COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020058: IPR020060; KEGG: sun:SUN_1138 glutamylglutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; SPTR: Glutamyl-tRNA synthetase 2; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family; Belongs to the class-I aminoacyl-tRNA synthetase family. (439 aa)
ADV46572.1Protein of unknown function DUF59; COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR002744: IPR002052; KEGG: sun:SUN_0995 metal-sulfur cluster biosynthetic enzyme; PFAM: protein of unknown function DUF59; SPTR: Metal-sulfur cluster biosynthetic enzyme; PFAM: Domain of unknown function DUF59. (117 aa)
ADV46575.1Iron-regulated ABC transporter ATPase subunit SufC; COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR003439: IPR003593: IPR017871: IPR010230; KEGG: sun:SUN_0998 Fe-S cluster assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Fe-S cluster assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC. (251 aa)
ADV46586.1KEGG: mag:amb2853 hypothetical protein; SPTR: Putative uncharacterized protein. (330 aa)
ADV46587.1Hypothetical protein; InterPro IPR011761; KEGG: mag:amb2853 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: RimK-like ATP-grasp domain. (333 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (651 aa)
ADV46591.1KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. (328 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (340 aa)
ADV46596.1GTP-binding signal recognition particle SRP54 G- domain protein; COGs: COG1419 Flagellar GTP-binding protein; InterPro IPR000897: IPR003593; KEGG: sun:SUN_1041 flagellar biosynthesis protein FlhF; PFAM: GTP-binding signal recognition particle SRP54 G- domain; SMART: AAA ATPase; SPTR: Flagellar biosynthesis protein FlhF; PFAM: SRP54-type protein, GTPase domain. (353 aa)
ADV46597.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550: IPR002052; KEGG: nis:NIS_0432 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosp [...] (186 aa)
ADV46624.1UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212: IPR014016: IPR014017; KEGG: sun:SUN_0384 ATP-dependent DNA helicase UvrD; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase, UvrD/REP family; PFAM: UvrD/REP helicase. (685 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (259 aa)
ADV46671.1Lipopolysaccharide biosynthesis protein; InterPro IPR003856; KEGG: nam:NAMH_1653 chain length determinant protein; PFAM: lipopolysaccharide biosynthesis protein; SPTR: Chain length determinant protein; PFAM: Chain length determinant protein. (284 aa)
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (188 aa)
hldED-alpha,beta-D-heptose 7-phosphate 1-kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (477 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (391 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (470 aa)
ADV46703.1Mur ligase middle domain protein; COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR013221: IPR004101; KEGG: sun:SUN_0832 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- -D-alanyl- D-alanine ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain. (472 aa)
ADV46724.1Conserved hypothetical protein CHP00245; COGs: COG0390 ABC-type uncharacterized transport system permease component; InterPro IPR005226; KEGG: pin:Ping_0175 hypothetical protein; PFAM: Conserved hypothetical protein CHP00245; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0014); TIGRFAM: conserved hypothetical protein TIGR00245. (230 aa)
ADV46751.1Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. (440 aa)
ADV46755.1DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545: IPR001650: IPR014001: IPR000629: IPR 014021: IPR014014; KEGG: sun:SUN_1297 ATP-dependent RNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (421 aa)
ADV46756.1ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR004176: IPR003959: IPR013093: IPR019489: IPR 001270: IPR003593: IPR018368; KEGG: nis:NIS_0876 ATP-dependent Clp protease, ATP-binding subunit ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpB; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellu [...] (858 aa)
purCCOGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636: IPR018236; KEGG: sun:SUN_1461 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. (239 aa)
purSPhosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (80 aa)
purQPhosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (227 aa)
queCpreQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (225 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (367 aa)
ADV46784.1Hypothetical protein; InterPro IPR011761; KEGG: nam:NAMH_0703 hypothetical protein; SPTR: Putative uncharacterized protein. (340 aa)
ADV46788.1COGs: COG0514 Superfamily II DNA helicase; InterProIPR014001: IPR001650: IPR002121: IPR014021: IPR 011545: IPR018982: IPR018329: IPR006293; KEGG: sun:SUN_2266 ATP-dependent DNA helicase RecQ; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; RQC domain; HRDC domain protein; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein; SPTR: ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: [...] (594 aa)
gatAaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (449 aa)
ADV46819.1ABC transporter related protein; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: nis:NIS_1522 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter. (230 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (859 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (275 aa)
ADV46832.1ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: sun:SUN_0316 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter. (216 aa)
ADV46845.1Protein of unknown function DUF59; COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR002744; KEGG: sun:SUN_0298 hypothetical protein; PFAM: protein of unknown function DUF59; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF59. (103 aa)
ADV46879.1Riboflavin kinase; COGs: COG0196 FAD synthase; InterPro IPR015864: IPR015865; KEGG: sun:SUN_0463 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: Riboflavin kinase; FAD synthetase; SPTR: Riboflavin biosynthesis regulatory protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase. (272 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (443 aa)
gatCaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (96 aa)
ADV46900.1Twitching motility protein; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR003593: IPR001482: IPR006321; KEGG: sun:SUN_0485 twitching motility protein PilT; PFAM: type II secretion system protein E; SMART: AAA ATPase; SPTR: Twitching motility protein PilT; TIGRFAM: twitching motility protein; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT. (351 aa)
lysSCOGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR002313: IPR018149: IPR006195: IPR004365: IPR 004364; KEGG: sun:SUN_0482 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family. (520 aa)
ADV46905.1Domain of unknown function DUF1882; InterPro IPR015061; KEGG: sun:SUN_0476 hypothetical protein; PFAM: Domain of unknown function DUF1882; SPTR: Putative uncharacterized protein; manually curated; PFAM: Domain of unknown function (DUF1882). (179 aa)
ADV46906.1Sporulation domain-containing protein; InterPro IPR007730; KEGG: sun:SUN_0472 hypothetical protein; PFAM: Sporulation domain-containing protein; SPTR: Putative uncharacterized protein; PFAM: Sporulation related domain. (243 aa)
ADV46909.16-phospho 3-hexuloisomerase; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347: IPR017552; KEGG: apo:Arcpr_0694 6-phospho 3-hexuloisomerase; PFAM: sugar isomerase (SIS); PRIAM: 6-phospho-3-hexuloisomerase; SPTR: 6-phospho 3-hexuloisomerase; TIGRFAM: 6-phospho 3-hexuloisomerase; PFAM: SIS domain; TIGRFAM: 6-phospho 3-hexuloisomerase. (177 aa)
ADV46911.1ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (372 aa)
ADV46914.1Two component transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789: IPR002197; KEGG: sun:SUN_0521 two-component response regulator; PFAM: response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; SPTR: Two-component response regulator; PFAM: Response regulator receiver domain. (294 aa)
ADV46926.1Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR001757: IPR001756: IPR001877: IPR006121: IPR 008250: IPR005834: IPR006403: IPR006416: IPR018303; KEGG: sun:SUN_1930 heavy-metal transporting P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Heavy-metal transporting P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 [...] (804 aa)
ftsHMembrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (696 aa)
ADV46951.1Amino acid ABC transporter ATP-binding protein, PAAT family; COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: ant:Arnit_0578 ABC transporter-like protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter. (287 aa)
ADV46953.1KEGG: sun:SUN_2081 hypothetical protein; SPTR: Putative uncharacterized protein. (322 aa)
ADV46978.1Capsular exopolysaccharide family; COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR003856: IPR005702; KEGG: sun:SUN_1559 capsular polysaccharide biosynthesis protein; PFAM: lipopolysaccharide biosynthesis protein; PRIAM: Non-specific protein-tyrosine kinase; SPTR: Capsular polysaccharide biosynthesis protein; TIGRFAM: capsular exopolysaccharide family; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family. (780 aa)
ADV46983.1DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014001: IPR001650: IPR014021: IPR014014: IPR 011545: IPR000629; KEGG: nis:NIS_1709 DEAD-box ATP dependent DNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent RNA helicase, DEAD-box family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (477 aa)
ADV47039.1Terminase GpA; COGs: COG5525 Bacteriophage tail assembly protein; InterPro IPR008866; KEGG: syf:Synpcc7942_0731 putative phage terminase large subunit; PFAM: terminase GpA; SPTR: Putative phage terminase large subunit; manually curated; PFAM: Phage terminase large subunit (GpA). (613 aa)
ADV47072.1COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR000795: IPR004161: IPR015191: IPR005225: IPR 004535; KEGG: nam:NAMH_1325 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 3; SPTR: Selenocysteine-specific translation elongation factor; TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor SelB, winged helix; Elongation factor Tu GTP binding do [...] (608 aa)
ADV47079.1ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (359 aa)
ADV47084.1ABC transporter related protein; COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: nis:NIS_1593 sulfonate/nitrate ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Sulfonate/nitrate ABC transporter, ATP-binding protein; PFAM: ABC transporter. (245 aa)
moaAGTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (322 aa)
ADV47122.1ABC transporter related protein; COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: sun:SUN_1584 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter. (240 aa)
ADV47130.1Appr-1-p processing domain protein; COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: sun:SUN_1457 hypothetical protein; PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; SPTR: Putative uncharacterized protein; PFAM: Macro domain. (177 aa)
groSChaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (88 aa)
groLChaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (545 aa)
infBBacterial translation initiation factor 2 (bIF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (885 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (294 aa)
ADV47157.1COGs: COG0469 Pyruvate kinase; InterPro IPR001697: IPR015793: IPR015794; KEGG: sun:SUN_0436 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (490 aa)
ribAGTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (188 aa)
ADV47173.1UvrD/REP helicase; COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR014016: IPR014017: IPR000212; KEGG: sun:SUN_0187 putative recombination protein RecB; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase, UvrD/REP family; PFAM: Domain of unknown function DUF83; UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (915 aa)
ddlD-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (349 aa)
carACOGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR006274: IPR017926: IPR002474: IPR000991: IPR 001317: IPR011702: IPR006220; KEGG: sun:SUN_0176 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: Carbamoylphosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (372 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (417 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (191 aa)
fusATranslation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] (693 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1385 aa)
tufTranslation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (402 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (771 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (464 aa)
ADV47240.1ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR017871: IPR003439: IPR017940: IPR003593; KEGG: wsu:WS0052 hypothetical protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: WLAB PROTEIN; manually curated; PFAM: ABC transporter transmembrane region; ABC transporter. (571 aa)
ADV47242.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa)
mutS2Smr protein/MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (732 aa)
ADV47249.1UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (440 aa)
ADV47268.1Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (478 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (627 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (657 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (701 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. (344 aa)
ADV47299.1COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR006426: IPR017932: IPR000583: IPR001962; KEGG: tdn:Suden_0163 asparagine synthase, glutamine-hydrolyzing; PFAM: asparagine synthase; glutamine amidotransferase class-II; SPTR: Asparagine synthase, glutamine-hydrolyzing; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). (605 aa)
ADV47316.1Thiamine biosynthesis protein:ExsB; COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; KEGG: sdl:Sdel_1979 thiamine biosynthesis protein:ExsB; SPTR: Thiamine biosynthesis protein:ExsB; PFAM: Thiamine biosynthesis protein (ThiI). (328 aa)
glnSCOGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterProIPR004514: IPR001412: IPR020058: IPR020059: IPR 018027: IPR020060; KEGG: sun:SUN_1139 glutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain; Asn/Gln amidotransferase; SPTR: Glutaminyl-tRNA synthetase; TIGRFAM: glutaminyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; GatB domain; tRNA synthetases class I (E and Q), anti-codon binding domain; TIGRFAM: glutaminyl-tRNA synthetase. (758 aa)
ADV47339.1ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR017871: IPR003439: IPR003593; KEGG: sun:SUN_0279 multidrug ABC transporter; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Multidrug ABC transporter; PFAM: ABC transporter. (539 aa)
thrSSer-tRNA(Thr) hydrolase; COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR002320: IPR006195: IPR012947: IPR002314: IPR 004154: IPR018158; KEGG: sun:SUN_2425 threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Threonyl/alanyl tRNA synthetase SAD; Anticodon-binding domain protein; SPTR: Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRN [...] (605 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR004733: IPR000728: IPR010918; KEGG: sun:SUN_2360 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoim [...] (333 aa)
ADV47357.1GTP-binding protein TypA; COGs: COG1217 membrane GTPase involved in stress response; InterProIPR005225: IPR006298: IPR000795: IPR004161: IPR 000640; KEGG: sun:SUN_2356 GTP-binding protein TypA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding protei [...] (607 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (442 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (543 aa)
folECOGs: COG0302 GTP cyclohydrolase I; InterPro IPR001474: IPR018234: IPR020602; KEGG: sun:SUN_0009 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. (193 aa)
ADV45286.1Mg chelatase, subunit ChlI; COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482: IPR000523; KEGG: sun:SUN_0014 Mg chelatase-related protein; PFAM: magnesium chelatase ChlI subunit; SPTR: Mg chelatase-related protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein. (520 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (195 aa)
ADV45297.1Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (706 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa)
ADV45312.1NLP/P60 protein; COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR018392: IPR000064: IPR002482; KEGG: sun:SUN_2355 hypothetical protein; PFAM: NLP/P60 protein; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Putative uncharacterized protein; PFAM: NlpC/P60 family; LysM domain. (556 aa)
ADV45318.1Type II secretion system protein E (GspE); COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR001482: IPR003593; KEGG: sun:SUN_0031 type II secretion system protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase; SPTR: Type II secretion system protein E; PFAM: Type II/IV secretion system protein. (507 aa)
ADV45329.1Recombination protein MgsA; COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959: IPR003593; KEGG: sun:SUN_2362 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: ATPase, AAA family; PFAM: MgsA AAA+ ATPase C terminal; Holliday junction DNA helicase ruvB N-terminus. (396 aa)
ADV45332.1KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR004800: IPR001347: IPR000644; KEGG: sun:SUN_2364 arabinose-5-phosphate isomerase; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: Arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. (331 aa)
ADV45341.1Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa)
ADV45357.1ABC transporter related protein; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: nam:NAMH_0736 cobalt import ATP-binding protein CbiO 2; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter-related protein; PFAM: ABC transporter. (245 aa)
ADV45368.1KEGG: sun:SUN_2319 hypothetical protein; SPTR: Putative uncharacterized protein. (359 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (434 aa)
ADV45412.1ABC transporter related protein; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR017871: IPR003439: IPR003593; KEGG: nis:NIS_0018 sulfate ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Sulfate ABC transporter, ATP-binding protein; PFAM: ABC transporter. (345 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (305 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa)
argSCOGs: COG0018 Arginyl-tRNA synthetase; InterProIPR001278: IPR001412: IPR005148: IPR015945: IPR 008909; KEGG: sun:SUN_2208 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase. (565 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (188 aa)
pgkCOGs: COG0126 3-phosphoglycerate kinase; InterPro IPR015911: IPR001576; KEGG: sun:SUN_2203 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (402 aa)
recARecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (347 aa)
ADV45494.1KEGG: nis:NIS_0453 hypothetical protein; SPTR: Phage-related protein. (404 aa)
purTFormate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (388 aa)
nnrECarbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (472 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (337 aa)
ADV45533.1ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR011703: IPR003593; KEGG: sun:SUN_1058 hypothetical protein; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: Putative uncharacterized protein; PFAM: ATPase family associated with various cellular activities (AAA). (333 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (615 aa)
leuSCOGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002302: IPR001412: IPR015945; KEGG: sun:SUN_2044 leucyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; SPTR: Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; Belongs to the class-I aminoacyl-tRNA synthetase family. (812 aa)
ADV45540.1FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645: IPR018109; KEGG: sun:SUN_2042 folylpolyglutamate synthase; SPTR: Folylpolyglutamate synthase; TIGRFAM: FolC bifunctional protein; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase. (416 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (998 aa)
ADV45543.1ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR011703: IPR016366; KEGG: sun:SUN_2006 AAA family ATPase; PFAM: ATPase associated with various cellular activities AAA_3; SPTR: ATPase, AAA family; PFAM: ATPase family associated with various cellular activities (AAA). (314 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (223 aa)
ADV45557.1ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018368: IPR001270: IPR004176: IPR 003959: IPR013093: IPR019489: IPR003593; KEGG: sun:SUN_2065 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-sm [...] (733 aa)
ADV45560.1Twitching motility protein; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR006321: IPR001482: IPR003593; KEGG: sun:SUN_2062 twitching motility protein PilT; PFAM: type II secretion system protein E; SMART: AAA ATPase; SPTR: Twitching motility protein PilT; TIGRFAM: twitching motility protein; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT. (385 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (385 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa)
selDSelenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. (344 aa)
ADV45586.1KEGG: syn:slr1442 hypothetical protein; SPTR: Slr1442 protein. (299 aa)
pheSCOGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR006195: IPR004529: IPR004188: IPR002319; KEGG: sun:SUN_0546 phenylalanyl-tRNA synthetase subunit alpha; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; SPTR: Phenylalanyl-tRNA synthetase alpha chain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe [...] (330 aa)
pheTCOGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterPro IPR002547: IPR005121: IPR004532: IPR005147; KEGG: sun:SUN_0547 phenylalanyl-tRNA synthetase subunit beta; PFAM: ferredoxin-fold anticodon-binding; t-RNA-binding domain-containing protein; tRNA synthetase B5; SPTR: Phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial. (778 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (390 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (414 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (451 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (291 aa)
ADV45656.1COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: sun:SUN_0599 hypothetical protein; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: Putative uncharacterized protein; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase. (189 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (312 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (283 aa)
ADV45670.1COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439: IPR017871: IPR003593; KEGG: sun:SUN_0604 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter. (648 aa)
lonATP-dependent proteinase; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (805 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (514 aa)
ADV45696.1Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (122 aa)
obgGTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (385 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (263 aa)
ADV45710.1COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: sun:SUN_1778 chromosome partitioning protein, ATPase ParA; SPTR: Chromosome partitioning protein, ATPase ParA; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. (260 aa)
atpAATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (504 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (295 aa)
atpDATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (468 aa)
atpCATP synthase F1 subcomplex epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (129 aa)
htpGHeat shock protein Hsp90; Molecular chaperone. Has ATPase activity. (624 aa)
purDCOGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR011761: IPR000115: IPR020559: IPR020562: IPR 020561: IPR020560; KEGG: sun:SUN_1891 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Pho [...] (424 aa)
ADV45729.1Heat shock protein DnaJ domain protein; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623: IPR003095; KEGG: nis:NIS_1334 heat shock protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Heat shock protein; PFAM: DnaJ domain. (85 aa)
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (378 aa)
dnaKChaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (627 aa)
ADV45755.1Diacylglycerol kinase catalytic region; COGs: COG1597 Sphingosine kinase; InterPro IPR001206: IPR005218; KEGG: vpa:VPA0693 lipid kinase; PFAM: diacylglycerol kinase catalytic region; SPTR: Probable lipid kinase yegS-like; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family; lipid kinase YegS. (301 aa)
ADV45756.1UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (427 aa)
ADV45772.1ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: sun:SUN_2172 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter. (217 aa)
ADV45789.1ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: abu:Abu_2114 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter. (227 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (313 aa)
ADV45797.1Putative transcriptional acitvator, Baf family; COGs: COG1521 Putative transcriptional regulator protein; InterPro IPR004619; KEGG: sun:SUN_0423 pantothenate kinase; PFAM: Bvg accessory factor; SPTR: Transcriptional activator, Baf family; TIGRFAM: transcriptional activator, Baf family; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III. (206 aa)
hisGATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (207 aa)
ADV45812.1ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: nis:NIS_0112 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter. (237 aa)
glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (602 aa)
ADV45844.1ATP citrate lyase subunit 1; COGs: COG0045 Succinyl-CoA synthetase beta subunit; InterPro IPR013650; KEGG: sun:SUN_0541 ATP citrate synthase, subunit 1; PFAM: ATP-grasp domain protein; SPTR: ATP citrate synthase, subunit 1; PFAM: ATP-grasp domain. (439 aa)
hisICOGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR008179: IPR002496: IPR021130; KEGG: sun:SUN_0237 histidine biosynthesis bifunctional protein HisI; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Histidine biosynthesis bifunctional protein HisI; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. (221 aa)
ADV45855.1DNA mismatch repair protein MutS domain protein; COGs: COG0249 Mismatch repair ATPase (MutS family); InterPro IPR007696: IPR000432: IPR007695; KEGG: sdl:Sdel_0624 DNA mismatch repair protein MutS domain protein; PFAM: DNA mismatch repair protein MutS domain protein; MutS III domain protein; SMART: DNA mismatch repair protein MutS domain protein; MutS III domain protein; SPTR: DNA mismatch repair protein MutS domain protein; PFAM: HNH endonuclease; MutS domain V; MutS domain I; MutS domain III. (978 aa)
ADV45892.1ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: sun:SUN_1062 Mn2+/Zn2+ ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Mn2+/Zn2+ ABC transporter, ATP-binding protein; PFAM: ABC transporter. (267 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (918 aa)
ADV45899.1NLP/P60 protein; COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064: IPR007730; KEGG: sun:SUN_0449 hypothetical protein; PFAM: NLP/P60 protein; Sporulation domain-containing protein; SPTR: Putative uncharacterized protein; PFAM: NlpC/P60 family; Sporulation related domain. (273 aa)
ADV45906.1COGs: COG0527 Aspartokinase; InterProIPR005260: IPR001341: IPR018042: IPR001048: IPR 002912; KEGG: sun:SUN_0456 aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (401 aa)
ADV45914.1ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR003593: IPR003439: IPR017940: IPR017871: IPR 001140; KEGG: sdl:Sdel_1055 ABC transporter related protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter; ABC transporter transmembrane region. (573 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (320 aa)
derRibosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (462 aa)
ADV45924.1COGs: COG1200 RecG-like helicase; InterPro IPR014001: IPR001650: IPR014021: IPR011545; KEGG: sun:SUN_1915 ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent DNA recombinase RecG; manually curated; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecG. (606 aa)
ADV45948.1KEGG: sun:SUN_2081 hypothetical protein; SPTR: Putative uncharacterized protein. (309 aa)
ADV45954.1Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (367 aa)
glyQCOGs: COG0752 Glycyl-tRNA synthetase alpha subunit; InterPro IPR002310: IPR006194; KEGG: sun:SUN_0359 glycyl-tRNA synthetase subunit alpha; PFAM: glycyl-tRNA synthetase alpha subunit; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, alpha subunit. (297 aa)
ffhSignal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...] (451 aa)
gatBaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (477 aa)
glySCOGs: COG0751 Glycyl-tRNA synthetase beta subunit; InterPro IPR002311: IPR015944: IPR006194; KEGG: sun:SUN_1701 glycyl-tRNA synthetase subunit beta; PFAM: glycyl-tRNA synthetase beta subunit; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase, beta subunit; TIGRFAM: glycyl-tRNA synthetase, beta subunit; PFAM: Glycyl-tRNA synthetase beta subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit. (684 aa)
eraGTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (302 aa)
ADV45986.1COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR001482: IPR007831; KEGG: sun:SUN_1672 general secretory pathway protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SPTR: General secretory pathway protein E; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain. (585 aa)
ADV46003.1KEGG: sun:SUN_2076 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Coenzyme PQQ synthesis protein D (PqqD). (90 aa)
ADV46006.1KEGG: sun:SUN_2081 hypothetical protein; SPTR: Putative uncharacterized protein. (303 aa)
ADV46008.1Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (944 aa)
ruvAHolliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (187 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)
ADV46034.1COGs: COG3869 Arginine kinase; InterPro IPR000749; KEGG: sun:SUN_1812 arginine kinase; PFAM: ATP:guanido phosphotransferase; PRIAM: Arginine kinase; SPTR: Arginine kinase; PFAM: ATP:guanido phosphotransferase, N-terminal domain; ATP:guanido phosphotransferase, C-terminal catalytic domain; Belongs to the ATP:guanido phosphotransferase family. (344 aa)
ADV46041.1COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR002123: IPR020845: IPR011701: IPR000873; KEGG: aap:NT05HA_0762 2-acyl-glycerophospho-ethanolamine acyltransferase; PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; major facilitator superfamily MFS_1; SMART: phospholipid/glycerol acyltransferase; SPTR: 2-acyl-glycerophospho-ethanolamine acyltransferase; PFAM: Acyltransferase; Major Facilitator Superfamily; AMP-binding enzyme; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases. (1146 aa)
ADV46046.1DNA translocase FtsK; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593: IPR002543: IPR018541; KEGG: sun:SUN_1351 cell division protein FtsK; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; SPTR: Cell division protein FtsK; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family. (811 aa)
ADV46075.1Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: wsu:WS1466 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC TRANSPORT SYSTEM ATP-BINDING PROTEIN; PFAM: ABC transporter. (230 aa)
ADV46076.1Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003593: IPR003439: IPR018170: IPR017871; KEGG: sdl:Sdel_0478 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter. (258 aa)
ADV46082.1GCN5-related N-acetyltransferase; InterPro IPR000182: IPR003594; KEGG: sun:SUN_0170 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; ATP-binding region ATPase domain protein; SPTR: Putative uncharacterized protein; PFAM: Acetyltransferase (GNAT) family; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (488 aa)
ADV46091.1ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR003593: IPR016366: IPR011703; KEGG: sun:SUN_2006 AAA family ATPase; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: ATPase, AAA family; PFAM: ATPase family associated with various cellular activities (AAA). (312 aa)
ADV46093.1InterPro IPR002035; KEGG: nam:NAMH_0436 von Willebrand factor, type A; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: von Willebrand factor, type A; PFAM: von Willebrand factor type A domain. (560 aa)
ADV46117.1ABC transporter related protein; COGs: COG2884 ATPase involved in cell division; InterPro IPR003593: IPR003439: IPR017871; KEGG: sun:SUN_1750 cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Cell division ATP-binding protein FtsE; PFAM: ABC transporter. (224 aa)
ADV46118.1InterPro IPR013055; KEGG: sun:SUN_1749 cell division protein FtsX; SPTR: Cell division protein FtsX. (271 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (237 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (400 aa)
ADV46145.1Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (425 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (571 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (199 aa)
aspSaspartate--tRNA(Asn) ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (592 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (213 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (633 aa)
ADV46191.1COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439: IPR003593; KEGG: sun:SUN_1475 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter. (531 aa)
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (256 aa)
ADV46202.1OstA family protein; COGs: COG1934 conserved hypothetical protein; InterPro IPR005653; KEGG: hps:HPSH_08170 hypothetical protein; PFAM: OstA family protein; SPTR: Putative uncharacterized protein; PFAM: OstA-like protein; TIGRFAM: lipopolysaccharide transport periplasmic protein LptA. (167 aa)
engBRibosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (206 aa)
hisSCOGs: COG0124 Histidyl-tRNA synthetase; InterProIPR015807: IPR004516: IPR006195: IPR002314: IPR 004154; KEGG: sun:SUN_1355 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase. (405 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (191 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa)
ADV46217.1Plasma-membrane proton-efflux P-type ATPase; COGs: COG0474 Cation transport ATPase; InterProIPR006534: IPR001757: IPR018303: IPR004014: IPR 008250: IPR005834: IPR000695; KEGG: sun:SUN_1289 H+-transporting P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; PRIAM: Proton-exporting ATPase; SPTR: H+-transporting P-type ATPase; TIGRFAM: plasma-membrane proton-efflux P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hyd [...] (906 aa)
ADV46219.1Plasma-membrane proton-efflux P-type ATPase; COGs: COG0474 Cation transport ATPase; InterProIPR006534: IPR001757: IPR018303: IPR004014: IPR 008250: IPR005834: IPR000695; KEGG: sun:SUN_1289 H+-transporting P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; PRIAM: Proton-exporting ATPase; SPTR: H+-transporting P-type ATPase; TIGRFAM: plasma-membrane proton-efflux P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hyd [...] (917 aa)
ADV46226.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa)
ADV46239.1KEGG: pph:Ppha_2636 hypothetical protein; SPTR: Putative uncharacterized protein. (177 aa)
ADV46240.1KEGG: psp:PSPPH_4785 ATP-binding protein; SPTR: Probable ATP-binding protein NMA0346. (340 aa)
ADV46246.1ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: nis:NIS_0938 hypothetical protein; PFAM: ROK family protein; SPTR: Putative uncharacterized protein; PFAM: ROK family. (258 aa)
ADV46265.1COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: sun:SUN_1276 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase. (417 aa)
ADV46267.16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (319 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (843 aa)
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
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