(16 nodes) Innate Immune System network (Ferroplasma acidiphilum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ntpE	A-type ATP synthase subunit E. (189 aa)
	ntpB	A-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (458 aa)
	serS	seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (443 aa)
	FAD_0362	Glycogen debranching protein. (610 aa)
	FAD_0562	Bifunctional phosphoglucose/phosphomannose isomerase. (305 aa)
	FAD_0829	Nicotinate phosphoribosyltransferase. (386 aa)
	FAD_1345	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (322 aa)
	psmB	Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (210 aa)
	mre11	DNA repair protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. (373 aa)
	psmA	Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (234 aa)
	tuf	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (426 aa)
	ntpI	A-type ATP synthase subunit I; Belongs to the V-ATPase 116 kDa subunit family. (642 aa)
	ntpD	A-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (216 aa)
	ntpA	A-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (589 aa)
	ntpF	A-type ATP synthase subunit F. (102 aa)
	ntpC	A-type ATP synthase subunit C. (353 aa)

Your Current Organism:

Ferroplasma acidiphilum

NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAD_0562	ntpB	FAD_0562	FAD_1820	Bifunctional phosphoglucose/phosphomannose isomerase.	A-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	0.532
FAD_0562	serS	FAD_0562	FAD_0347	Bifunctional phosphoglucose/phosphomannose isomerase.	seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).	0.457
ntpA	ntpB	FAD_1821	FAD_1820	A-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	A-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	0.999
ntpA	ntpC	FAD_1821	FAD_1823	A-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	A-type ATP synthase subunit C.	0.999
ntpA	ntpD	FAD_1821	FAD_1819	A-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	A-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
ntpA	ntpE	FAD_1821	FAD_1824	A-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	A-type ATP synthase subunit E.	0.999
ntpA	ntpF	FAD_1821	FAD_1822	A-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	A-type ATP synthase subunit F.	0.999
ntpA	ntpI	FAD_1821	FAD_1817	A-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	A-type ATP synthase subunit I; Belongs to the V-ATPase 116 kDa subunit family.	0.999
ntpA	tuf	FAD_1821	FAD_1649	A-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	0.521
ntpB	FAD_0562	FAD_1820	FAD_0562	A-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	Bifunctional phosphoglucose/phosphomannose isomerase.	0.532
ntpB	ntpA	FAD_1820	FAD_1821	A-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	A-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	0.999
ntpB	ntpC	FAD_1820	FAD_1823	A-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	A-type ATP synthase subunit C.	0.999
ntpB	ntpD	FAD_1820	FAD_1819	A-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	A-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
ntpB	ntpE	FAD_1820	FAD_1824	A-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	A-type ATP synthase subunit E.	0.999
ntpB	ntpF	FAD_1820	FAD_1822	A-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	A-type ATP synthase subunit F.	0.999
ntpB	ntpI	FAD_1820	FAD_1817	A-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	A-type ATP synthase subunit I; Belongs to the V-ATPase 116 kDa subunit family.	0.999
ntpC	ntpA	FAD_1823	FAD_1821	A-type ATP synthase subunit C.	A-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	0.999
ntpC	ntpB	FAD_1823	FAD_1820	A-type ATP synthase subunit C.	A-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	0.999
ntpC	ntpD	FAD_1823	FAD_1819	A-type ATP synthase subunit C.	A-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
ntpC	ntpE	FAD_1823	FAD_1824	A-type ATP synthase subunit C.	A-type ATP synthase subunit E.	0.999