(13 nodes) Macropinocytosis, and Protein kinase C inhibitor activity network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107576554	Mitogen-activated protein kinase-activated protein kinase 2. (368 aa)
	LOC107598307	Heat shock protein beta-1-like. (204 aa)
	LOC107574676	Mitogen-activated protein kinase-activated protein kinase 3. (410 aa)
	LOC107587387	Heat shock protein beta-1-like. (204 aa)
	ENSSGRP00000038698	Mitogen-activated protein kinase 13-like isoform X1. (316 aa)
	LOC107598961	Mitogen-activated protein kinase 13-like. (367 aa)
	LOC107590153	Mitogen-activated protein kinase-activated protein kinase 2. (383 aa)
	ENSSGRP00000054874	Si:dkey-1k23.3. (389 aa)
	LOC107553980	Mitogen-activated protein kinase 12. (364 aa)
	ENSSGRP00000090211	MAPK activated protein kinase 3. (391 aa)
	LOC107549293	Mitogen-activated protein kinase-activated protein kinase 2. (386 aa)
	ENSSGRP00000103378	Uncharacterized protein LOC107561263. (205 aa)
	LOC107550950	Mitogen-activated protein kinase-activated protein kinase 2. (400 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000038698	ENSSGRP00000090211	ENSSGRP00000038698	ENSSGRP00000090211	Mitogen-activated protein kinase 13-like isoform X1.	MAPK activated protein kinase 3.	0.793
ENSSGRP00000038698	LOC107549293	ENSSGRP00000038698	ENSSGRP00000092166	Mitogen-activated protein kinase 13-like isoform X1.	Mitogen-activated protein kinase-activated protein kinase 2.	0.917
ENSSGRP00000038698	LOC107550950	ENSSGRP00000038698	ENSSGRP00000112715	Mitogen-activated protein kinase 13-like isoform X1.	Mitogen-activated protein kinase-activated protein kinase 2.	0.918
ENSSGRP00000038698	LOC107574676	ENSSGRP00000038698	ENSSGRP00000014887	Mitogen-activated protein kinase 13-like isoform X1.	Mitogen-activated protein kinase-activated protein kinase 3.	0.924
ENSSGRP00000038698	LOC107576554	ENSSGRP00000038698	ENSSGRP00000006554	Mitogen-activated protein kinase 13-like isoform X1.	Mitogen-activated protein kinase-activated protein kinase 2.	0.920
ENSSGRP00000038698	LOC107590153	ENSSGRP00000038698	ENSSGRP00000045822	Mitogen-activated protein kinase 13-like isoform X1.	Mitogen-activated protein kinase-activated protein kinase 2.	0.917
ENSSGRP00000054874	ENSSGRP00000090211	ENSSGRP00000054874	ENSSGRP00000090211	Si:dkey-1k23.3.	MAPK activated protein kinase 3.	0.843
ENSSGRP00000054874	LOC107549293	ENSSGRP00000054874	ENSSGRP00000092166	Si:dkey-1k23.3.	Mitogen-activated protein kinase-activated protein kinase 2.	0.851
ENSSGRP00000054874	LOC107550950	ENSSGRP00000054874	ENSSGRP00000112715	Si:dkey-1k23.3.	Mitogen-activated protein kinase-activated protein kinase 2.	0.851
ENSSGRP00000054874	LOC107574676	ENSSGRP00000054874	ENSSGRP00000014887	Si:dkey-1k23.3.	Mitogen-activated protein kinase-activated protein kinase 3.	0.843
ENSSGRP00000054874	LOC107576554	ENSSGRP00000054874	ENSSGRP00000006554	Si:dkey-1k23.3.	Mitogen-activated protein kinase-activated protein kinase 2.	0.851
ENSSGRP00000054874	LOC107590153	ENSSGRP00000054874	ENSSGRP00000045822	Si:dkey-1k23.3.	Mitogen-activated protein kinase-activated protein kinase 2.	0.851
ENSSGRP00000090211	ENSSGRP00000038698	ENSSGRP00000090211	ENSSGRP00000038698	MAPK activated protein kinase 3.	Mitogen-activated protein kinase 13-like isoform X1.	0.793
ENSSGRP00000090211	ENSSGRP00000054874	ENSSGRP00000090211	ENSSGRP00000054874	MAPK activated protein kinase 3.	Si:dkey-1k23.3.	0.843
ENSSGRP00000090211	ENSSGRP00000103378	ENSSGRP00000090211	ENSSGRP00000103378	MAPK activated protein kinase 3.	Uncharacterized protein LOC107561263.	0.843
ENSSGRP00000090211	LOC107549293	ENSSGRP00000090211	ENSSGRP00000092166	MAPK activated protein kinase 3.	Mitogen-activated protein kinase-activated protein kinase 2.	0.805
ENSSGRP00000090211	LOC107550950	ENSSGRP00000090211	ENSSGRP00000112715	MAPK activated protein kinase 3.	Mitogen-activated protein kinase-activated protein kinase 2.	0.806
ENSSGRP00000090211	LOC107553980	ENSSGRP00000090211	ENSSGRP00000065273	MAPK activated protein kinase 3.	Mitogen-activated protein kinase 12.	0.791
ENSSGRP00000090211	LOC107576554	ENSSGRP00000090211	ENSSGRP00000006554	MAPK activated protein kinase 3.	Mitogen-activated protein kinase-activated protein kinase 2.	0.808
ENSSGRP00000090211	LOC107587387	ENSSGRP00000090211	ENSSGRP00000026930	MAPK activated protein kinase 3.	Heat shock protein beta-1-like.	0.843