(20 nodes) TOR complex, and Regulation of TORC2 signaling network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107594963	Serine/threonine-protein kinase mTOR-like. (2549 aa)
	LOC107577586	Uncharacterized protein LOC107577586. (204 aa)
	LOC107581528	DEP domain-containing mTOR-interacting protein-like isoform X1. (381 aa)
	mapkap1	Target of rapamycin complex 2 subunit MAPKAP1 isoform X1. (526 aa)
	mlst8	Target of rapamycin complex subunit LST8. (326 aa)
	ENSSGRP00000022625	Uncharacterized protein LOC107551160. (356 aa)
	LOC107596624	DEP domain-containing mTOR-interacting protein-like. (380 aa)
	ENSSGRP00000035783	Rapamycin-insensitive companion of mTOR-like. (1355 aa)
	LOC107553319	Regulatory-associated protein of mTOR-like isoform X1. (1362 aa)
	ENSSGRP00000052319	Proline-rich protein 5-like. (211 aa)
	LOC107564227	Serine/threonine-protein kinase mTOR. (2552 aa)
	LOC107567655	Rapamycin-insensitive companion of mTOR-like. (1661 aa)
	ENSSGRP00000068111	MTOR associated protein, LST8 homolog (S. cerevisiae). (194 aa)
	LOC107583676	Ras-related GTP-binding protein D-like. (397 aa)
	rptor	Regulatory-associated protein of mTOR isoform X1. (1363 aa)
	LOC107591490	Target of rapamycin complex 2 subunit MAPKAP1-like. (522 aa)
	ENSSGRP00000094661	Rapamycin-insensitive companion of mTOR-like isoform X1. (1710 aa)
	LOC107574131	Proline-rich protein 5-like. (456 aa)
	ENSSGRP00000107261	DEP domain-containing mTOR-interacting protein-like. (434 aa)
	LOC107576702	Ribosomal protein S6 kinase beta-1-like. (352 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000022625	ENSSGRP00000035783	ENSSGRP00000022625	ENSSGRP00000035783	Uncharacterized protein LOC107551160.	Rapamycin-insensitive companion of mTOR-like.	0.563
ENSSGRP00000022625	ENSSGRP00000052319	ENSSGRP00000022625	ENSSGRP00000052319	Uncharacterized protein LOC107551160.	Proline-rich protein 5-like.	0.626
ENSSGRP00000022625	ENSSGRP00000068111	ENSSGRP00000022625	ENSSGRP00000068111	Uncharacterized protein LOC107551160.	MTOR associated protein, LST8 homolog (S. cerevisiae).	0.983
ENSSGRP00000022625	ENSSGRP00000094661	ENSSGRP00000022625	ENSSGRP00000094661	Uncharacterized protein LOC107551160.	Rapamycin-insensitive companion of mTOR-like isoform X1.	0.563
ENSSGRP00000022625	ENSSGRP00000107261	ENSSGRP00000022625	ENSSGRP00000107261	Uncharacterized protein LOC107551160.	DEP domain-containing mTOR-interacting protein-like.	0.909
ENSSGRP00000022625	LOC107553319	ENSSGRP00000022625	ENSSGRP00000038059	Uncharacterized protein LOC107551160.	Regulatory-associated protein of mTOR-like isoform X1.	0.999
ENSSGRP00000022625	LOC107564227	ENSSGRP00000022625	ENSSGRP00000054966	Uncharacterized protein LOC107551160.	Serine/threonine-protein kinase mTOR.	0.998
ENSSGRP00000022625	LOC107567655	ENSSGRP00000022625	ENSSGRP00000067318	Uncharacterized protein LOC107551160.	Rapamycin-insensitive companion of mTOR-like.	0.563
ENSSGRP00000022625	LOC107574131	ENSSGRP00000022625	ENSSGRP00000096846	Uncharacterized protein LOC107551160.	Proline-rich protein 5-like.	0.641
ENSSGRP00000022625	LOC107576702	ENSSGRP00000022625	ENSSGRP00000110060	Uncharacterized protein LOC107551160.	Ribosomal protein S6 kinase beta-1-like.	0.966
ENSSGRP00000022625	LOC107577586	ENSSGRP00000022625	ENSSGRP00000005071	Uncharacterized protein LOC107551160.	Uncharacterized protein LOC107577586.	0.900
ENSSGRP00000022625	LOC107581528	ENSSGRP00000022625	ENSSGRP00000007878	Uncharacterized protein LOC107551160.	DEP domain-containing mTOR-interacting protein-like isoform X1.	0.909
ENSSGRP00000022625	LOC107583676	ENSSGRP00000022625	ENSSGRP00000069184	Uncharacterized protein LOC107551160.	Ras-related GTP-binding protein D-like.	0.912
ENSSGRP00000022625	LOC107591490	ENSSGRP00000022625	ENSSGRP00000089729	Uncharacterized protein LOC107551160.	Target of rapamycin complex 2 subunit MAPKAP1-like.	0.965
ENSSGRP00000022625	LOC107594963	ENSSGRP00000022625	ENSSGRP00000003759	Uncharacterized protein LOC107551160.	Serine/threonine-protein kinase mTOR-like.	0.998
ENSSGRP00000022625	LOC107596624	ENSSGRP00000022625	ENSSGRP00000024376	Uncharacterized protein LOC107551160.	DEP domain-containing mTOR-interacting protein-like.	0.909
ENSSGRP00000022625	mapkap1	ENSSGRP00000022625	ENSSGRP00000009533	Uncharacterized protein LOC107551160.	Target of rapamycin complex 2 subunit MAPKAP1 isoform X1.	0.965
ENSSGRP00000022625	mlst8	ENSSGRP00000022625	ENSSGRP00000009599	Uncharacterized protein LOC107551160.	Target of rapamycin complex subunit LST8.	0.996
ENSSGRP00000022625	rptor	ENSSGRP00000022625	ENSSGRP00000084096	Uncharacterized protein LOC107551160.	Regulatory-associated protein of mTOR isoform X1.	0.999
ENSSGRP00000035783	ENSSGRP00000022625	ENSSGRP00000035783	ENSSGRP00000022625	Rapamycin-insensitive companion of mTOR-like.	Uncharacterized protein LOC107551160.	0.563