(34 nodes) One carbon pool by folate, and Glycine catabolic process network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000004123	annotation not available (368 aa)
	ENSSGRP00000006866	annotation not available (310 aa)
	ENSSGRP00000009494	Aminomethyltransferase. (252 aa)
	LOC107585700	Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. (423 aa)
	LOC107584586	Folylpolyglutamate synthase, mitochondrial-like. (575 aa)
	LOC107584745	Glycine cleavage system H protein, mitochondrial-like. (175 aa)
	LOC107602465	Methylenetetrahydrofolate reductase (NADPH). (679 aa)
	ENSSGRP00000026999	Dihydrofolate reductase-like. (180 aa)
	Mtr	5-methyltetrahydrofolate--homocysteine methyltransferase. (1104 aa)
	ENSSGRP00000031541	Glycine dehydrogenase (decarboxylating). (861 aa)
	ENSSGRP00000036551	annotation not available (520 aa)
	LOC107581728	Serine hydroxymethyltransferase, cytosolic-like. (497 aa)
	ENSSGRP00000050275	Thymidylate synthetase. (305 aa)
	ENSSGRP00000052543	Glycine cleavage system H protein, mitochondrial-like. (170 aa)
	ENSSGRP00000053716	Serine hydroxymethyltransferase, mitochondrial-like. (456 aa)
	ftcd	Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase. (540 aa)
	LOC107556039	Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase. (372 aa)
	mthfs	5-formyltetrahydrofolate cyclo-ligase isoform X1. (200 aa)
	Amt	Aminomethyltransferase, mitochondrial. (401 aa)
	ENSSGRP00000059735	Methylenetetrahydrofolate reductase (NADPH). (75 aa)
	mthfd1	C-1-tetrahydrofolate synthase, cytoplasmic isoform X1. (951 aa)
	LOC107600162	Glycine cleavage system H protein, mitochondrial-like. (181 aa)
	LOC107585466	Folylpolyglutamate synthase, mitochondrial-like. (575 aa)
	LOC107553959	Dihydrofolate reductase-like isoform X1. (193 aa)
	LOC107564915	Glycine cleavage system H protein, mitochondrial-like. (174 aa)
	gldc	Glycine dehydrogenase (decarboxylating), mitochondrial. (1020 aa)
	ENSSGRP00000072187	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (334 aa)
	ENSSGRP00000072753	Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase. (329 aa)
	ENSSGRP00000082871	LOW QUALITY PROTEIN: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like. (904 aa)
	Dhfr	Dihydrofolate reductase. (184 aa)
	LOC107558017	Putative transferase CAF17 homolog, mitochondrial. (347 aa)
	LOC107596429	Methionyl-tRNA formyltransferase, mitochondrial-like. (398 aa)
	LOC107593877	Putative transferase CAF17 homolog, mitochondrial. (360 aa)
	LOC107565988	Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase. (347 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Amt	Dhfr	ENSSGRP00000058788	ENSSGRP00000088520	Aminomethyltransferase, mitochondrial.	Dihydrofolate reductase.	0.973
Amt	ENSSGRP00000004123	ENSSGRP00000058788	ENSSGRP00000004123	Aminomethyltransferase, mitochondrial.	annotation not available	0.849
Amt	ENSSGRP00000006866	ENSSGRP00000058788	ENSSGRP00000006866	Aminomethyltransferase, mitochondrial.	annotation not available	0.824
Amt	ENSSGRP00000026999	ENSSGRP00000058788	ENSSGRP00000026999	Aminomethyltransferase, mitochondrial.	Dihydrofolate reductase-like.	0.973
Amt	ENSSGRP00000031541	ENSSGRP00000058788	ENSSGRP00000031541	Aminomethyltransferase, mitochondrial.	Glycine dehydrogenase (decarboxylating).	0.996
Amt	ENSSGRP00000050275	ENSSGRP00000058788	ENSSGRP00000050275	Aminomethyltransferase, mitochondrial.	Thymidylate synthetase.	0.824
Amt	ENSSGRP00000052543	ENSSGRP00000058788	ENSSGRP00000052543	Aminomethyltransferase, mitochondrial.	Glycine cleavage system H protein, mitochondrial-like.	0.998
Amt	ENSSGRP00000053716	ENSSGRP00000058788	ENSSGRP00000053716	Aminomethyltransferase, mitochondrial.	Serine hydroxymethyltransferase, mitochondrial-like.	0.985
Amt	ENSSGRP00000059735	ENSSGRP00000058788	ENSSGRP00000059735	Aminomethyltransferase, mitochondrial.	Methylenetetrahydrofolate reductase (NADPH).	0.988
Amt	ENSSGRP00000072187	ENSSGRP00000058788	ENSSGRP00000072187	Aminomethyltransferase, mitochondrial.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.	0.923
Amt	ENSSGRP00000072753	ENSSGRP00000058788	ENSSGRP00000072753	Aminomethyltransferase, mitochondrial.	Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase.	0.992
Amt	ENSSGRP00000082871	ENSSGRP00000058788	ENSSGRP00000082871	Aminomethyltransferase, mitochondrial.	LOW QUALITY PROTEIN: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like.	0.957
Amt	LOC107553959	ENSSGRP00000058788	ENSSGRP00000064462	Aminomethyltransferase, mitochondrial.	Dihydrofolate reductase-like isoform X1.	0.973
Amt	LOC107556039	ENSSGRP00000058788	ENSSGRP00000057895	Aminomethyltransferase, mitochondrial.	Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase.	0.992
Amt	LOC107558017	ENSSGRP00000058788	ENSSGRP00000096520	Aminomethyltransferase, mitochondrial.	Putative transferase CAF17 homolog, mitochondrial.	0.873
Amt	LOC107564915	ENSSGRP00000058788	ENSSGRP00000067835	Aminomethyltransferase, mitochondrial.	Glycine cleavage system H protein, mitochondrial-like.	0.998
Amt	LOC107565988	ENSSGRP00000058788	ENSSGRP00000111762	Aminomethyltransferase, mitochondrial.	Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase.	0.992
Amt	LOC107581728	ENSSGRP00000058788	ENSSGRP00000045083	Aminomethyltransferase, mitochondrial.	Serine hydroxymethyltransferase, cytosolic-like.	0.985
Amt	LOC107584586	ENSSGRP00000058788	ENSSGRP00000012355	Aminomethyltransferase, mitochondrial.	Folylpolyglutamate synthase, mitochondrial-like.	0.681
Amt	LOC107584745	ENSSGRP00000058788	ENSSGRP00000012696	Aminomethyltransferase, mitochondrial.	Glycine cleavage system H protein, mitochondrial-like.	0.998