(32 nodes) Sterol biosynthetic process, and 3-beta-hydroxy-delta5-steroid dehydrogenase activity network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000002511	Squalene epoxidase b. (371 aa)
	SDR42E1	Short-chain dehydrogenase/reductase family 42E member 1. (353 aa)
	LOC107580338	5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase-like. (510 aa)
	fdft1	Farnesyl-diphosphate farnesyltransferase. (451 aa)
	ENSSGRP00000013239	annotation not available (43 aa)
	ENSSGRP00000013630	7-dehydrocholesterol reductase-like isoform X1. (470 aa)
	LOC107567893	Cholesterol 25-hydroxylase-like protein 1, member 2. (276 aa)
	LOC107548349	Methylsterol monooxygenase 1-like. (291 aa)
	LOC107584736	7-dehydrocholesterol reductase. (457 aa)
	LOC107568024	Lanosterol 14-alpha demethylase. (503 aa)
	ENSSGRP00000034181	Sigma non-opioid intracellular receptor 1-like. (201 aa)
	LOC107555490	3-hydroxy-3-methylglutaryl-coenzyme A reductase-like. (906 aa)
	ENSSGRP00000042886	Lanosterol synthase-like. (386 aa)
	LOC107552346	Phosphoethanolamine N-methyltransferase 3-like isoform X1. (500 aa)
	ENSSGRP00000052410	Squalene synthase-like. (294 aa)
	LOC107573076	Sigma non-opioid intracellular receptor 1. (222 aa)
	hmgcs1	Hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1. (580 aa)
	ENSSGRP00000072389	Short chain dehydrogenase/reductase family 42E, member 1. (376 aa)
	ENSSGRP00000076529	Cholesterol 25-hydroxylase like 1, tandem duplicate 1. (232 aa)
	LOC107554123	3 beta-hydroxysteroid dehydrogenase type 7-like isoform X1. (367 aa)
	Faxdc2	Fatty acid hydroxylase domain-containing protein 2. (236 aa)
	nsdhl	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating. (383 aa)
	LOC107561054	Delta7-sterol 5-desaturase. (298 aa)
	LOC107596343	Phosphoethanolamine N-methyltransferase 3-like isoform X1. (498 aa)
	ENSSGRP00000096012	Squalene monooxygenase-like. (535 aa)
	LOC107558014	5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase-like. (510 aa)
	ERG28	Probable ergosterol biosynthetic protein 28. (143 aa)
	LOC107548136	Delta7-sterol 5-desaturase. (362 aa)
	LOC107584572	Cholesterol 25-hydroxylase-like protein 2. (290 aa)
	LOC107556968	Squalene monooxygenase-like. (557 aa)
	LOC107566150	Delta(24)-sterol reductase-like isoform X1. (516 aa)
	LOC107551038	17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase. (359 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000002511	ENSSGRP00000013239	ENSSGRP00000002511	ENSSGRP00000013239	Squalene epoxidase b.	annotation not available	0.922
ENSSGRP00000002511	ENSSGRP00000013630	ENSSGRP00000002511	ENSSGRP00000013630	Squalene epoxidase b.	7-dehydrocholesterol reductase-like isoform X1.	0.908
ENSSGRP00000002511	ENSSGRP00000034181	ENSSGRP00000002511	ENSSGRP00000034181	Squalene epoxidase b.	Sigma non-opioid intracellular receptor 1-like.	0.953
ENSSGRP00000002511	ENSSGRP00000042886	ENSSGRP00000002511	ENSSGRP00000042886	Squalene epoxidase b.	Lanosterol synthase-like.	0.995
ENSSGRP00000002511	ENSSGRP00000052410	ENSSGRP00000002511	ENSSGRP00000052410	Squalene epoxidase b.	Squalene synthase-like.	0.922
ENSSGRP00000002511	ENSSGRP00000072389	ENSSGRP00000002511	ENSSGRP00000072389	Squalene epoxidase b.	Short chain dehydrogenase/reductase family 42E, member 1.	0.877
ENSSGRP00000002511	ENSSGRP00000076529	ENSSGRP00000002511	ENSSGRP00000076529	Squalene epoxidase b.	Cholesterol 25-hydroxylase like 1, tandem duplicate 1.	0.899
ENSSGRP00000002511	ERG28	ENSSGRP00000002511	ENSSGRP00000101122	Squalene epoxidase b.	Probable ergosterol biosynthetic protein 28.	0.719
ENSSGRP00000002511	Faxdc2	ENSSGRP00000002511	ENSSGRP00000082382	Squalene epoxidase b.	Fatty acid hydroxylase domain-containing protein 2.	0.899
ENSSGRP00000002511	LOC107548136	ENSSGRP00000002511	ENSSGRP00000103611	Squalene epoxidase b.	Delta7-sterol 5-desaturase.	0.865
ENSSGRP00000002511	LOC107548349	ENSSGRP00000002511	ENSSGRP00000024478	Squalene epoxidase b.	Methylsterol monooxygenase 1-like.	0.905
ENSSGRP00000002511	LOC107551038	ENSSGRP00000002511	ENSSGRP00000113050	Squalene epoxidase b.	17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase.	0.818
ENSSGRP00000002511	LOC107552346	ENSSGRP00000002511	ENSSGRP00000048257	Squalene epoxidase b.	Phosphoethanolamine N-methyltransferase 3-like isoform X1.	0.684
ENSSGRP00000002511	LOC107554123	ENSSGRP00000002511	ENSSGRP00000082154	Squalene epoxidase b.	3 beta-hydroxysteroid dehydrogenase type 7-like isoform X1.	0.877
ENSSGRP00000002511	LOC107555490	ENSSGRP00000002511	ENSSGRP00000040207	Squalene epoxidase b.	3-hydroxy-3-methylglutaryl-coenzyme A reductase-like.	0.904
ENSSGRP00000002511	LOC107558014	ENSSGRP00000002511	ENSSGRP00000096522	Squalene epoxidase b.	5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase-like.	0.747
ENSSGRP00000002511	LOC107561054	ENSSGRP00000002511	ENSSGRP00000091783	Squalene epoxidase b.	Delta7-sterol 5-desaturase.	0.865
ENSSGRP00000002511	LOC107566150	ENSSGRP00000002511	ENSSGRP00000112696	Squalene epoxidase b.	Delta(24)-sterol reductase-like isoform X1.	0.640
ENSSGRP00000002511	LOC107567893	ENSSGRP00000002511	ENSSGRP00000021617	Squalene epoxidase b.	Cholesterol 25-hydroxylase-like protein 1, member 2.	0.899
ENSSGRP00000002511	LOC107568024	ENSSGRP00000002511	ENSSGRP00000032183	Squalene epoxidase b.	Lanosterol 14-alpha demethylase.	0.986