(20 nodes) Mixed, incl. Pyridine nucleotide biosynthesis, and NAD synthase network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000006120	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like. (224 aa)
	LOC107583111	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3-like. (249 aa)
	ENSSGRP00000012336	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like. (211 aa)
	NADSYN1	NAD synthetase 1. (551 aa)
	nudt12	Peroxisomal NADH pyrophosphatase NUDT12. (278 aa)
	ENSSGRP00000029182	Glutamine-dependent NAD(+) synthetase-like. (567 aa)
	nmnat1	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1. (274 aa)
	NMNAT3	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3-like. (249 aa)
	ENSSGRP00000045402	5'-nucleotidase-like. (569 aa)
	LOC107590159	Nicotinamide phosphoribosyltransferase-like. (522 aa)
	LOC107557267	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2. (304 aa)
	naprt	Nicotinate phosphoribosyltransferase isoform X1. (549 aa)
	LOC107568197	NAD-dependent protein lipoamidase sirtuin-4, mitochondrial-like. (309 aa)
	LOC107553976	NAD-dependent protein deacetylase sirtuin-3-like. (380 aa)
	nampt	Nicotinamide phosphoribosyltransferase. (493 aa)
	ENSSGRP00000086024	Nicotinate phosphoribosyltransferase-like. (512 aa)
	LOC107549391	Nicotinamide/nicotinate riboside kinase. (202 aa)
	LOC107550476	Nicotinamide phosphoribosyltransferase-like. (498 aa)
	ENSSGRP00000101525	NAD-dependent protein deacetylase sirtuin-6-like. (362 aa)
	LOC107581358	Probable 8-oxo-dGTP diphosphatase NUDT15. (172 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000006120	ENSSGRP00000012336	ENSSGRP00000006120	ENSSGRP00000012336	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like.	0.909
ENSSGRP00000006120	ENSSGRP00000029182	ENSSGRP00000006120	ENSSGRP00000029182	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Glutamine-dependent NAD(+) synthetase-like.	0.939
ENSSGRP00000006120	ENSSGRP00000101525	ENSSGRP00000006120	ENSSGRP00000101525	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	NAD-dependent protein deacetylase sirtuin-6-like.	0.662
ENSSGRP00000006120	LOC107550476	ENSSGRP00000006120	ENSSGRP00000099006	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Nicotinamide phosphoribosyltransferase-like.	0.715
ENSSGRP00000006120	LOC107553976	ENSSGRP00000006120	ENSSGRP00000064449	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	NAD-dependent protein deacetylase sirtuin-3-like.	0.684
ENSSGRP00000006120	LOC107557267	ENSSGRP00000006120	ENSSGRP00000048640	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2.	0.742
ENSSGRP00000006120	LOC107568197	ENSSGRP00000006120	ENSSGRP00000061050	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	NAD-dependent protein lipoamidase sirtuin-4, mitochondrial-like.	0.586
ENSSGRP00000006120	LOC107583111	ENSSGRP00000006120	ENSSGRP00000009102	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3-like.	0.742
ENSSGRP00000006120	LOC107590159	ENSSGRP00000006120	ENSSGRP00000048146	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Nicotinamide phosphoribosyltransferase-like.	0.715
ENSSGRP00000006120	NADSYN1	ENSSGRP00000006120	ENSSGRP00000013695	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	NAD synthetase 1.	0.415
ENSSGRP00000006120	NMNAT3	ENSSGRP00000006120	ENSSGRP00000043716	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3-like.	0.742
ENSSGRP00000006120	nampt	ENSSGRP00000006120	ENSSGRP00000085030	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Nicotinamide phosphoribosyltransferase.	0.741
ENSSGRP00000006120	nmnat1	ENSSGRP00000006120	ENSSGRP00000031385	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1.	0.742
ENSSGRP00000006120	nudt12	ENSSGRP00000006120	ENSSGRP00000019333	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Peroxisomal NADH pyrophosphatase NUDT12.	0.916
ENSSGRP00000012336	ENSSGRP00000006120	ENSSGRP00000012336	ENSSGRP00000006120	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like.	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	0.909
ENSSGRP00000012336	ENSSGRP00000029182	ENSSGRP00000012336	ENSSGRP00000029182	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like.	Glutamine-dependent NAD(+) synthetase-like.	0.909
ENSSGRP00000012336	ENSSGRP00000045402	ENSSGRP00000012336	ENSSGRP00000045402	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like.	5'-nucleotidase-like.	0.524
ENSSGRP00000012336	ENSSGRP00000101525	ENSSGRP00000012336	ENSSGRP00000101525	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like.	NAD-dependent protein deacetylase sirtuin-6-like.	0.913
ENSSGRP00000012336	LOC107550476	ENSSGRP00000012336	ENSSGRP00000099006	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like.	Nicotinamide phosphoribosyltransferase-like.	0.941
ENSSGRP00000012336	LOC107553976	ENSSGRP00000012336	ENSSGRP00000064449	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1-like.	NAD-dependent protein deacetylase sirtuin-3-like.	0.918