(51 nodes) Heme metabolic process, and Iron import into the mitochondrion network (Sinocyclocheilus grahami)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107596028	Delta-aminolevulinic acid dehydratase-like. (348 aa)
	ENSSGRP00000003904	Heme oxygenase-like. (606 aa)
	ENSSGRP00000004690	annotation not available (113 aa)
	ENSSGRP00000005026	Porphobilinogen deaminase-like. (137 aa)
	CNNM1	Cyclin and CBS domain divalent metal cation transport mediator 1. (496 aa)
	ENSSGRP00000007734	Cytochrome c-type heme lyase-like. (169 aa)
	ENSSGRP00000010164	Uroporphyrinogen-III synthase-like. (102 aa)
	ENSSGRP00000012154	annotation not available (182 aa)
	LOC107559740	Delta-aminolevulinic acid dehydratase-like. (331 aa)
	cp	Ceruloplasmin. (1128 aa)
	ENSSGRP00000016006	Hydroxymethylbilane synthase a. (338 aa)
	ENSSGRP00000016504	annotation not available (142 aa)
	LOC107599292	Biliverdin reductase A-like. (333 aa)
	LOC107585846	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial-like. (446 aa)
	ENSSGRP00000019885	Solute carrier family 25 member 38-B isoform X1. (299 aa)
	ENSSGRP00000020439	Spermatogenesis associated 20. (663 aa)
	LOC107551169	Solute carrier family 25 member 39 isoform X1. (359 aa)
	LOC107550392	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial-like. (444 aa)
	ENSSGRP00000026491	Solute carrier family 25 member 39-like isoform X1. (376 aa)
	LOC107597563	Porphobilinogen deaminase-like. (358 aa)
	LOC107572806	Solute carrier family 25 member 38-A-like. (311 aa)
	ppox	Protoporphyrinogen/coproporphyrinogen III oxidase. (477 aa)
	LOC107559231	Heme oxygenase-like. (272 aa)
	LOC107552914	ATP-binding cassette sub-family B member 10, mitochondrial-like. (651 aa)
	LOC107601050	Solute carrier family 25 (mitochondrial iron transporter), member 28/37. (396 aa)
	fech	Protoporphyrin/coproporphyrin ferrochelatase. (442 aa)
	LOC107601585	Heme oxygenase 2-like isoform X1. (320 aa)
	LOC107594665	Cytochrome c-type heme lyase-like isoform X1. (277 aa)
	LOC107550203	Transmembrane protein 14C. (116 aa)
	LOC107596696	Magnesium transporter MRS2 homolog, mitochondrial-like. (423 aa)
	spata20	Spermatogenesis-associated protein 20 isoform X1. (818 aa)
	ENSSGRP00000066068	annotation not available (314 aa)
	Uros	Uroporphyrinogen-III synthase. (195 aa)
	ENSSGRP00000070463	Cytochrome c-type heme lyase-like. (311 aa)
	COX10	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1. (443 aa)
	LOC107566667	Heme oxygenase 2-like. (290 aa)
	ENSSGRP00000076975	Porphobilinogen deaminase-like. (252 aa)
	ENSSGRP00000077666	Hydroxymethylbilane synthase, b. (301 aa)
	ENSSGRP00000078017	Solute carrier family 25 member 28. (198 aa)
	ENSSGRP00000079716	Solute carrier family 22 member 4. (403 aa)
	ENDOV	Endonuclease V isoform X1. (252 aa)
	blvrb	Biliverdin reductase / flavin reductase. (207 aa)
	LOC107559458	Solute carrier family 25 (mitochondrial iron transporter), member 28/37. (351 aa)
	ENSSGRP00000086299	Heme oxygenase-like. (268 aa)
	urod	Uroporphyrinogen decarboxylase isoform X1. (374 aa)
	LOC107563742	Solute carrier family 25 member 38-A. (274 aa)
	LOC107553648	Heme oxygenase 2-like isoform X1. (332 aa)
	LOC107553129	Solute carrier family 25 (mitochondrial iron transporter), member 28/37. (307 aa)
	LOC107601852	ATP-binding cassette sub-family B member 10, mitochondrial-like. (715 aa)
	blvra	Biliverdin reductase A. (293 aa)
	LOC107552663	Transmembrane protein 14C-like isoform X1. (107 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COX10	ENDOV	ENSSGRP00000072400	ENSSGRP00000084165	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Endonuclease V isoform X1.	0.636
COX10	ENSSGRP00000003904	ENSSGRP00000072400	ENSSGRP00000003904	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Heme oxygenase-like.	0.908
COX10	ENSSGRP00000005026	ENSSGRP00000072400	ENSSGRP00000005026	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Porphobilinogen deaminase-like.	0.510
COX10	ENSSGRP00000007734	ENSSGRP00000072400	ENSSGRP00000007734	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Cytochrome c-type heme lyase-like.	0.970
COX10	ENSSGRP00000010164	ENSSGRP00000072400	ENSSGRP00000010164	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Uroporphyrinogen-III synthase-like.	0.627
COX10	ENSSGRP00000012154	ENSSGRP00000072400	ENSSGRP00000012154	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	annotation not available	0.511
COX10	ENSSGRP00000016006	ENSSGRP00000072400	ENSSGRP00000016006	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Hydroxymethylbilane synthase a.	0.510
COX10	ENSSGRP00000070463	ENSSGRP00000072400	ENSSGRP00000070463	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Cytochrome c-type heme lyase-like.	0.970
COX10	ENSSGRP00000076975	ENSSGRP00000072400	ENSSGRP00000076975	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Porphobilinogen deaminase-like.	0.510
COX10	ENSSGRP00000077666	ENSSGRP00000072400	ENSSGRP00000077666	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Hydroxymethylbilane synthase, b.	0.510
COX10	ENSSGRP00000086299	ENSSGRP00000072400	ENSSGRP00000086299	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Heme oxygenase-like.	0.908
COX10	LOC107550392	ENSSGRP00000072400	ENSSGRP00000025139	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial-like.	0.636
COX10	LOC107553648	ENSSGRP00000072400	ENSSGRP00000091744	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Heme oxygenase 2-like isoform X1.	0.908
COX10	LOC107559231	ENSSGRP00000072400	ENSSGRP00000035317	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Heme oxygenase-like.	0.908
COX10	LOC107559740	ENSSGRP00000072400	ENSSGRP00000014328	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Delta-aminolevulinic acid dehydratase-like.	0.647
COX10	LOC107566667	ENSSGRP00000072400	ENSSGRP00000073704	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Heme oxygenase 2-like.	0.908
COX10	LOC107585846	ENSSGRP00000072400	ENSSGRP00000018459	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial-like.	0.636
COX10	LOC107594665	ENSSGRP00000072400	ENSSGRP00000058899	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Cytochrome c-type heme lyase-like isoform X1.	0.970
COX10	LOC107596028	ENSSGRP00000072400	ENSSGRP00000001595	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Delta-aminolevulinic acid dehydratase-like.	0.647
COX10	LOC107597563	ENSSGRP00000072400	ENSSGRP00000027209	Protoheme IX farnesyltransferase, mitochondrial-like isoform X1.	Porphobilinogen deaminase-like.	0.510