(11 nodes) Mixed, incl. Reelin-mediated signaling pathway, and Serine rich protein interaction domain network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107583722	Breast cancer anti-estrogen resistance protein 1-like isoform X1. (953 aa)
	LOC107599366	Rap guanine nucleotide exchange factor 1-like. (1099 aa)
	anapc7	Rap guanine nucleotide exchange factor 1-like. (1029 aa)
	ENSSGRP00000054500	Rap guanine nucleotide exchange factor 1-like. (601 aa)
	LOC107591716	Proto-oncogene C-crk. (305 aa)
	LOC107585573	Adapter molecule crk-like. (311 aa)
	LOC107582780	Rho-related GTP-binding protein RhoQ-like. (205 aa)
	LOC107589229	Proto-oncogene C-crk. (302 aa)
	ENSSGRP00000093131	Rap guanine nucleotide exchange factor 1-like. (1080 aa)
	LOC107596915	Breast cancer anti-estrogen resistance protein 1-like isoform X1. (936 aa)
	LOC107592606	Adapter molecule crk-like. (308 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000054500	ENSSGRP00000093131	ENSSGRP00000054500	ENSSGRP00000093131	Rap guanine nucleotide exchange factor 1-like.	Rap guanine nucleotide exchange factor 1-like.	0.901
ENSSGRP00000054500	LOC107582780	ENSSGRP00000054500	ENSSGRP00000086430	Rap guanine nucleotide exchange factor 1-like.	Rho-related GTP-binding protein RhoQ-like.	0.951
ENSSGRP00000054500	LOC107583722	ENSSGRP00000054500	ENSSGRP00000033236	Rap guanine nucleotide exchange factor 1-like.	Breast cancer anti-estrogen resistance protein 1-like isoform X1.	0.755
ENSSGRP00000054500	LOC107585573	ENSSGRP00000054500	ENSSGRP00000082168	Rap guanine nucleotide exchange factor 1-like.	Adapter molecule crk-like.	0.991
ENSSGRP00000054500	LOC107589229	ENSSGRP00000054500	ENSSGRP00000088376	Rap guanine nucleotide exchange factor 1-like.	Proto-oncogene C-crk.	0.991
ENSSGRP00000054500	LOC107591716	ENSSGRP00000054500	ENSSGRP00000054907	Rap guanine nucleotide exchange factor 1-like.	Proto-oncogene C-crk.	0.991
ENSSGRP00000054500	LOC107592606	ENSSGRP00000054500	ENSSGRP00000104456	Rap guanine nucleotide exchange factor 1-like.	Adapter molecule crk-like.	0.991
ENSSGRP00000054500	LOC107596915	ENSSGRP00000054500	ENSSGRP00000097109	Rap guanine nucleotide exchange factor 1-like.	Breast cancer anti-estrogen resistance protein 1-like isoform X1.	0.755
ENSSGRP00000093131	ENSSGRP00000054500	ENSSGRP00000093131	ENSSGRP00000054500	Rap guanine nucleotide exchange factor 1-like.	Rap guanine nucleotide exchange factor 1-like.	0.901
ENSSGRP00000093131	LOC107582780	ENSSGRP00000093131	ENSSGRP00000086430	Rap guanine nucleotide exchange factor 1-like.	Rho-related GTP-binding protein RhoQ-like.	0.951
ENSSGRP00000093131	LOC107583722	ENSSGRP00000093131	ENSSGRP00000033236	Rap guanine nucleotide exchange factor 1-like.	Breast cancer anti-estrogen resistance protein 1-like isoform X1.	0.781
ENSSGRP00000093131	LOC107585573	ENSSGRP00000093131	ENSSGRP00000082168	Rap guanine nucleotide exchange factor 1-like.	Adapter molecule crk-like.	0.991
ENSSGRP00000093131	LOC107589229	ENSSGRP00000093131	ENSSGRP00000088376	Rap guanine nucleotide exchange factor 1-like.	Proto-oncogene C-crk.	0.991
ENSSGRP00000093131	LOC107591716	ENSSGRP00000093131	ENSSGRP00000054907	Rap guanine nucleotide exchange factor 1-like.	Proto-oncogene C-crk.	0.991
ENSSGRP00000093131	LOC107592606	ENSSGRP00000093131	ENSSGRP00000104456	Rap guanine nucleotide exchange factor 1-like.	Adapter molecule crk-like.	0.991
ENSSGRP00000093131	LOC107596915	ENSSGRP00000093131	ENSSGRP00000097109	Rap guanine nucleotide exchange factor 1-like.	Breast cancer anti-estrogen resistance protein 1-like isoform X1.	0.781
LOC107582780	ENSSGRP00000054500	ENSSGRP00000086430	ENSSGRP00000054500	Rho-related GTP-binding protein RhoQ-like.	Rap guanine nucleotide exchange factor 1-like.	0.951
LOC107582780	ENSSGRP00000093131	ENSSGRP00000086430	ENSSGRP00000093131	Rho-related GTP-binding protein RhoQ-like.	Rap guanine nucleotide exchange factor 1-like.	0.951
LOC107582780	LOC107585573	ENSSGRP00000086430	ENSSGRP00000082168	Rho-related GTP-binding protein RhoQ-like.	Adapter molecule crk-like.	0.943
LOC107582780	LOC107589229	ENSSGRP00000086430	ENSSGRP00000088376	Rho-related GTP-binding protein RhoQ-like.	Proto-oncogene C-crk.	0.943