(13 nodes) Mixed, incl. PI3-kinase family, p85-binding domain, and Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000002662	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta. (430 aa)
	LOC107595995	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta. (727 aa)
	LOC107574159	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta. (1069 aa)
	LOC107598784	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like isoform X1. (1067 aa)
	ENSSGRP00000037164	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like. (1002 aa)
	ENSSGRP00000046124	RAC-gamma serine/threonine-protein kinase-like. (332 aa)
	LOC107552371	Insulin receptor substrate 2-like. (1037 aa)
	LOC107567258	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like isoform X1. (1073 aa)
	ENSSGRP00000081422	RAC-beta serine/threonine-protein kinase-like. (362 aa)
	LOC107557843	RAC-beta serine/threonine-protein kinase-like. (479 aa)
	LOC107586063	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta. (701 aa)
	LOC107596473	Insulin receptor substrate 2-B-like. (1155 aa)
	LOC107551943	Ras-related protein M-Ras-like isoform X1. (215 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000002662	ENSSGRP00000037164	ENSSGRP00000002662	ENSSGRP00000037164	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like.	0.841
ENSSGRP00000002662	ENSSGRP00000046124	ENSSGRP00000002662	ENSSGRP00000046124	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	RAC-gamma serine/threonine-protein kinase-like.	0.843
ENSSGRP00000002662	ENSSGRP00000081422	ENSSGRP00000002662	ENSSGRP00000081422	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	RAC-beta serine/threonine-protein kinase-like.	0.830
ENSSGRP00000002662	LOC107551943	ENSSGRP00000002662	ENSSGRP00000112385	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	Ras-related protein M-Ras-like isoform X1.	0.738
ENSSGRP00000002662	LOC107552371	ENSSGRP00000002662	ENSSGRP00000060417	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	Insulin receptor substrate 2-like.	0.881
ENSSGRP00000002662	LOC107557843	ENSSGRP00000002662	ENSSGRP00000088545	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	RAC-beta serine/threonine-protein kinase-like.	0.830
ENSSGRP00000002662	LOC107567258	ENSSGRP00000002662	ENSSGRP00000080212	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like isoform X1.	0.844
ENSSGRP00000002662	LOC107574159	ENSSGRP00000002662	ENSSGRP00000013844	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.841
ENSSGRP00000002662	LOC107596473	ENSSGRP00000002662	ENSSGRP00000109385	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	Insulin receptor substrate 2-B-like.	0.881
ENSSGRP00000002662	LOC107598784	ENSSGRP00000002662	ENSSGRP00000022121	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like isoform X1.	0.844
ENSSGRP00000037164	ENSSGRP00000002662	ENSSGRP00000037164	ENSSGRP00000002662	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.841
ENSSGRP00000037164	ENSSGRP00000046124	ENSSGRP00000037164	ENSSGRP00000046124	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like.	RAC-gamma serine/threonine-protein kinase-like.	0.841
ENSSGRP00000037164	ENSSGRP00000081422	ENSSGRP00000037164	ENSSGRP00000081422	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like.	RAC-beta serine/threonine-protein kinase-like.	0.841
ENSSGRP00000037164	LOC107551943	ENSSGRP00000037164	ENSSGRP00000112385	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like.	Ras-related protein M-Ras-like isoform X1.	0.859
ENSSGRP00000037164	LOC107552371	ENSSGRP00000037164	ENSSGRP00000060417	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like.	Insulin receptor substrate 2-like.	0.830
ENSSGRP00000037164	LOC107557843	ENSSGRP00000037164	ENSSGRP00000088545	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like.	RAC-beta serine/threonine-protein kinase-like.	0.841
ENSSGRP00000037164	LOC107586063	ENSSGRP00000037164	ENSSGRP00000099434	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.762
ENSSGRP00000037164	LOC107595995	ENSSGRP00000037164	ENSSGRP00000012677	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.841
ENSSGRP00000037164	LOC107596473	ENSSGRP00000037164	ENSSGRP00000109385	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like.	Insulin receptor substrate 2-B-like.	0.830
ENSSGRP00000046124	ENSSGRP00000002662	ENSSGRP00000046124	ENSSGRP00000002662	RAC-gamma serine/threonine-protein kinase-like.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.843