(6 nodes) PTK6 Down-Regulation, and PTK6 Activates STAT3 network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000017275	Signal transducing adaptor family member 2a. (358 aa)
	ENSSGRP00000017278	Uncharacterized protein LOC107599279. (270 aa)
	ENSSGRP00000040436	Tyrosine-protein kinase SRK3-like. (274 aa)
	ENSSGRP00000040437	annotation not available (192 aa)
	ENSSGRP00000066377	Tyrosine-protein kinase Srms-like. (158 aa)
	ENSSGRP00000105113	Signal-transducing adaptor protein 2-like. (364 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
ENSSGRP00000017275	ENSSGRP00000040436	Signal transducing adaptor family member 2a.	Tyrosine-protein kinase SRK3-like.	0.623
ENSSGRP00000017275	ENSSGRP00000040437	Signal transducing adaptor family member 2a.	annotation not available	0.623
ENSSGRP00000017275	ENSSGRP00000066377	Signal transducing adaptor family member 2a.	Tyrosine-protein kinase Srms-like.	0.623
ENSSGRP00000017278	ENSSGRP00000040436	Uncharacterized protein LOC107599279.	Tyrosine-protein kinase SRK3-like.	0.623
ENSSGRP00000017278	ENSSGRP00000040437	Uncharacterized protein LOC107599279.	annotation not available	0.623
ENSSGRP00000017278	ENSSGRP00000066377	Uncharacterized protein LOC107599279.	Tyrosine-protein kinase Srms-like.	0.623
ENSSGRP00000040436	ENSSGRP00000017275	Tyrosine-protein kinase SRK3-like.	Signal transducing adaptor family member 2a.	0.623
ENSSGRP00000040436	ENSSGRP00000017278	Tyrosine-protein kinase SRK3-like.	Uncharacterized protein LOC107599279.	0.623
ENSSGRP00000040436	ENSSGRP00000105113	Tyrosine-protein kinase SRK3-like.	Signal-transducing adaptor protein 2-like.	0.623
ENSSGRP00000040437	ENSSGRP00000017275	annotation not available	Signal transducing adaptor family member 2a.	0.623
ENSSGRP00000040437	ENSSGRP00000017278	annotation not available	Uncharacterized protein LOC107599279.	0.623
ENSSGRP00000040437	ENSSGRP00000105113	annotation not available	Signal-transducing adaptor protein 2-like.	0.623
ENSSGRP00000066377	ENSSGRP00000017275	Tyrosine-protein kinase Srms-like.	Signal transducing adaptor family member 2a.	0.623
ENSSGRP00000066377	ENSSGRP00000017278	Tyrosine-protein kinase Srms-like.	Uncharacterized protein LOC107599279.	0.623
ENSSGRP00000066377	ENSSGRP00000105113	Tyrosine-protein kinase Srms-like.	Signal-transducing adaptor protein 2-like.	0.623
ENSSGRP00000105113	ENSSGRP00000040436	Signal-transducing adaptor protein 2-like.	Tyrosine-protein kinase SRK3-like.	0.623
ENSSGRP00000105113	ENSSGRP00000040437	Signal-transducing adaptor protein 2-like.	annotation not available	0.623
ENSSGRP00000105113	ENSSGRP00000066377	Signal-transducing adaptor protein 2-like.	Tyrosine-protein kinase Srms-like.	0.623