(25 nodes) Rap protein signal transduction, and Rap/ran-GAP network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107599760	Ras-related protein Rap-2B. (183 aa)
	ENSSGRP00000011191	annotation not available (117 aa)
	ENSSGRP00000013556	annotation not available (182 aa)
	ENSSGRP00000013564	RAP1 GTPase activating protein. (502 aa)
	ENSSGRP00000019340	RAP1 GTPase activating protein 2b. (695 aa)
	ENSSGRP00000020463	RAP1 GTPase activating protein. (636 aa)
	LOC107559797	Ras-related protein Rap-2A. (183 aa)
	ENSSGRP00000027656	Rap1 GTPase-activating protein 2-like isoform X1. (700 aa)
	ENSSGRP00000027863	Rap guanine nucleotide exchange factor 6-like. (1188 aa)
	ENSSGRP00000037061	RAP2A, member of RAS oncogene family a. (84 aa)
	DIRAS2	DIRAS family, GTP-binding Ras-like 2. (199 aa)
	rap1gap2	Rap1 GTPase-activating protein 2 isoform X1. (773 aa)
	ENSSGRP00000042482	Rap guanine nucleotide exchange factor (GEF) 3. (775 aa)
	ENSSGRP00000043078	Ras-related protein Rap-2b-like. (148 aa)
	rap1b	RAP1B, member of RAS oncogene family. (185 aa)
	LOC107601176	RAS guanyl-releasing protein 2-like. (625 aa)
	ENSSGRP00000070418	annotation not available (626 aa)
	ENSSGRP00000076063	RAP1B, member of RAS oncogene family. (126 aa)
	ENSSGRP00000085165	annotation not available (569 aa)
	LOC107549783	Ras-related protein Rap-2a-like. (183 aa)
	LOC107556193	DIRAS family, GTP-binding Ras-like 1. (195 aa)
	LOC107557907	Ras-related protein Rap-1A-like. (185 aa)
	ENSSGRP00000095202	Zgc:171558. (896 aa)
	ENSSGRP00000098575	Rap guanine nucleotide exchange factor (GEF) 4. (987 aa)
	ENSSGRP00000110619	annotation not available (701 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DIRAS2	ENSSGRP00000013556	ENSSGRP00000040710	ENSSGRP00000013556	DIRAS family, GTP-binding Ras-like 2.	annotation not available	0.565
DIRAS2	ENSSGRP00000013564	ENSSGRP00000040710	ENSSGRP00000013564	DIRAS family, GTP-binding Ras-like 2.	RAP1 GTPase activating protein.	0.565
DIRAS2	ENSSGRP00000019340	ENSSGRP00000040710	ENSSGRP00000019340	DIRAS family, GTP-binding Ras-like 2.	RAP1 GTPase activating protein 2b.	0.565
DIRAS2	ENSSGRP00000020463	ENSSGRP00000040710	ENSSGRP00000020463	DIRAS family, GTP-binding Ras-like 2.	RAP1 GTPase activating protein.	0.565
DIRAS2	ENSSGRP00000027656	ENSSGRP00000040710	ENSSGRP00000027656	DIRAS family, GTP-binding Ras-like 2.	Rap1 GTPase-activating protein 2-like isoform X1.	0.565
DIRAS2	ENSSGRP00000027863	ENSSGRP00000040710	ENSSGRP00000027863	DIRAS family, GTP-binding Ras-like 2.	Rap guanine nucleotide exchange factor 6-like.	0.480
DIRAS2	ENSSGRP00000042482	ENSSGRP00000040710	ENSSGRP00000042482	DIRAS family, GTP-binding Ras-like 2.	Rap guanine nucleotide exchange factor (GEF) 3.	0.504
DIRAS2	ENSSGRP00000070418	ENSSGRP00000040710	ENSSGRP00000070418	DIRAS family, GTP-binding Ras-like 2.	annotation not available	0.565
DIRAS2	ENSSGRP00000085165	ENSSGRP00000040710	ENSSGRP00000085165	DIRAS family, GTP-binding Ras-like 2.	annotation not available	0.565
DIRAS2	ENSSGRP00000095202	ENSSGRP00000040710	ENSSGRP00000095202	DIRAS family, GTP-binding Ras-like 2.	Zgc:171558.	0.504
DIRAS2	ENSSGRP00000098575	ENSSGRP00000040710	ENSSGRP00000098575	DIRAS family, GTP-binding Ras-like 2.	Rap guanine nucleotide exchange factor (GEF) 4.	0.751
DIRAS2	ENSSGRP00000110619	ENSSGRP00000040710	ENSSGRP00000110619	DIRAS family, GTP-binding Ras-like 2.	annotation not available	0.751
DIRAS2	LOC107601176	ENSSGRP00000040710	ENSSGRP00000059744	DIRAS family, GTP-binding Ras-like 2.	RAS guanyl-releasing protein 2-like.	0.589
DIRAS2	rap1gap2	ENSSGRP00000040710	ENSSGRP00000041952	DIRAS family, GTP-binding Ras-like 2.	Rap1 GTPase-activating protein 2 isoform X1.	0.565
ENSSGRP00000011191	ENSSGRP00000013556	ENSSGRP00000011191	ENSSGRP00000013556	annotation not available	annotation not available	0.565
ENSSGRP00000011191	ENSSGRP00000013564	ENSSGRP00000011191	ENSSGRP00000013564	annotation not available	RAP1 GTPase activating protein.	0.565
ENSSGRP00000011191	ENSSGRP00000019340	ENSSGRP00000011191	ENSSGRP00000019340	annotation not available	RAP1 GTPase activating protein 2b.	0.565
ENSSGRP00000011191	ENSSGRP00000020463	ENSSGRP00000011191	ENSSGRP00000020463	annotation not available	RAP1 GTPase activating protein.	0.565
ENSSGRP00000011191	ENSSGRP00000027656	ENSSGRP00000011191	ENSSGRP00000027656	annotation not available	Rap1 GTPase-activating protein 2-like isoform X1.	0.565
ENSSGRP00000011191	ENSSGRP00000027863	ENSSGRP00000011191	ENSSGRP00000027863	annotation not available	Rap guanine nucleotide exchange factor 6-like.	0.480