(48 nodes) Sema4D induced cell migration and growth-cone collapse, and Plexin cytoplasmic RasGAP domain network (Sinocyclocheilus grahami)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107593332	Semaphorin-4E-like. (796 aa)
	ENSSGRP00000006713	Rho-associated protein kinase 2-like. (144 aa)
	ENSSGRP00000007186	Plexin-B2-like. (1873 aa)
	ENSSGRP00000009213	Semaphorin-4E-like. (517 aa)
	LOC107556503	Rho-related GTP-binding protein RhoA-B-like. (200 aa)
	ENSSGRP00000017155	Rho-associated protein kinase 1-like. (1295 aa)
	LOC107599253	Semaphorin-4E-like. (757 aa)
	ENSSGRP00000035917	Plexin-B2-like. (238 aa)
	LOC107586348	Plexin-B1-like isoform X1. (2207 aa)
	LOC107600972	Rho-related GTP-binding protein RhoE-like. (243 aa)
	gna12	Guanine nucleotide-binding protein subunit alpha-12. (379 aa)
	ENSSGRP00000042491	Rho guanine nucleotide exchange factor (GEF) 11. (1366 aa)
	SEMA4D	Semaphorin-4D-like. (872 aa)
	ENSSGRP00000043383	annotation not available (114 aa)
	ENSSGRP00000043386	annotation not available (113 aa)
	ENSSGRP00000043915	Plexin-B1-like. (2017 aa)
	ENSSGRP00000044176	annotation not available (93 aa)
	ENSSGRP00000049486	T-lymphoma invasion and metastasis-inducing protein 1-like. (1520 aa)
	ENSSGRP00000052380	Rho guanine nucleotide exchange factor 18-like. (824 aa)
	LOC107586959	Rho-related GTP-binding protein RhoE. (243 aa)
	LOC107591763	Rho-related GTP-binding protein RhoA-D-like. (193 aa)
	LOC107555625	Rho-associated protein kinase 2-like isoform X1. (1497 aa)
	LOC107591788	Rho-related GTP-binding protein RhoA-B. (193 aa)
	LOC107586415	Semaphorin-4E-like isoform X1. (816 aa)
	PTPRC-2	Protein tyrosine phosphatase receptor type C. (1160 aa)
	ENSSGRP00000064186	Rho-associated protein kinase 2-like. (1382 aa)
	ENSSGRP00000064947	annotation not available (104 aa)
	LOC107563659	Rho-related GTP-binding protein Rho6-like. (232 aa)
	rnd3	Rho-related GTP-binding protein RhoE. (226 aa)
	ENSSGRP00000069320	Rho-associated, coiled-coil containing protein kinase 2a. (1333 aa)
	LOC107554062	Guanine nucleotide-binding protein subunit alpha-13-like. (376 aa)
	LOC107602474	Rho-associated protein kinase 2-like. (1158 aa)
	ENSSGRP00000074534	Rho guanine nucleotide exchange factor (GEF) 12a. (1166 aa)
	ENSSGRP00000076490	Rho guanine nucleotide exchange factor 18-like. (1142 aa)
	ENSSGRP00000077351	Plexin-B1-like isoform X1. (2125 aa)
	LOC107600769	Rho guanine nucleotide exchange factor 12-like isoform X1. (1482 aa)
	LOC107595767	Rho guanine nucleotide exchange factor 1-like isoform X1. (1038 aa)
	LOC107562777	Rho-related GTP-binding protein RhoA-D-like isoform X1. (193 aa)
	ENSSGRP00000094364	Semaphorin-4D-like isoform X1. (887 aa)
	LOC107586229	Rho guanine nucleotide exchange factor 12-like isoform X1. (1425 aa)
	ENSSGRP00000100518	annotation not available (261 aa)
	ENSSGRP00000100519	annotation not available (382 aa)
	ENSSGRP00000102054	LOW QUALITY PROTEIN: plexin-B1-like. (2210 aa)
	LOC107587155	Plexin-B2-like. (1865 aa)
	LOC107584085	Guanine nucleotide-binding protein subunit alpha-13-like. (388 aa)
	ENSSGRP00000106541	Rho guanine nucleotide exchange factor (GEF) 12b. (1407 aa)
	ENSSGRP00000108836	LIM domain kinase 1-like. (646 aa)
	LOC107555359	Rho-related GTP-binding protein RhoE-like. (226 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000006713	ENSSGRP00000042491	ENSSGRP00000006713	ENSSGRP00000042491	Rho-associated protein kinase 2-like.	Rho guanine nucleotide exchange factor (GEF) 11.	0.431
ENSSGRP00000006713	ENSSGRP00000074534	ENSSGRP00000006713	ENSSGRP00000074534	Rho-associated protein kinase 2-like.	Rho guanine nucleotide exchange factor (GEF) 12a.	0.431
ENSSGRP00000006713	ENSSGRP00000100518	ENSSGRP00000006713	ENSSGRP00000100518	Rho-associated protein kinase 2-like.	annotation not available	0.431
ENSSGRP00000006713	ENSSGRP00000100519	ENSSGRP00000006713	ENSSGRP00000100519	Rho-associated protein kinase 2-like.	annotation not available	0.431
ENSSGRP00000006713	ENSSGRP00000106541	ENSSGRP00000006713	ENSSGRP00000106541	Rho-associated protein kinase 2-like.	Rho guanine nucleotide exchange factor (GEF) 12b.	0.431
ENSSGRP00000006713	ENSSGRP00000108836	ENSSGRP00000006713	ENSSGRP00000108836	Rho-associated protein kinase 2-like.	LIM domain kinase 1-like.	0.753
ENSSGRP00000006713	LOC107554062	ENSSGRP00000006713	ENSSGRP00000073137	Rho-associated protein kinase 2-like.	Guanine nucleotide-binding protein subunit alpha-13-like.	0.416
ENSSGRP00000006713	LOC107555359	ENSSGRP00000006713	ENSSGRP00000110777	Rho-associated protein kinase 2-like.	Rho-related GTP-binding protein RhoE-like.	0.643
ENSSGRP00000006713	LOC107555625	ENSSGRP00000006713	ENSSGRP00000057591	Rho-associated protein kinase 2-like.	Rho-associated protein kinase 2-like isoform X1.	0.901
ENSSGRP00000006713	LOC107556503	ENSSGRP00000006713	ENSSGRP00000014115	Rho-associated protein kinase 2-like.	Rho-related GTP-binding protein RhoA-B-like.	0.934
ENSSGRP00000006713	LOC107562777	ENSSGRP00000006713	ENSSGRP00000083742	Rho-associated protein kinase 2-like.	Rho-related GTP-binding protein RhoA-D-like isoform X1.	0.904
ENSSGRP00000006713	LOC107563659	ENSSGRP00000006713	ENSSGRP00000066322	Rho-associated protein kinase 2-like.	Rho-related GTP-binding protein Rho6-like.	0.643
ENSSGRP00000006713	LOC107584085	ENSSGRP00000006713	ENSSGRP00000104627	Rho-associated protein kinase 2-like.	Guanine nucleotide-binding protein subunit alpha-13-like.	0.416
ENSSGRP00000006713	LOC107586229	ENSSGRP00000006713	ENSSGRP00000099190	Rho-associated protein kinase 2-like.	Rho guanine nucleotide exchange factor 12-like isoform X1.	0.431
ENSSGRP00000006713	LOC107586959	ENSSGRP00000006713	ENSSGRP00000056105	Rho-associated protein kinase 2-like.	Rho-related GTP-binding protein RhoE.	0.643
ENSSGRP00000006713	LOC107591763	ENSSGRP00000006713	ENSSGRP00000056909	Rho-associated protein kinase 2-like.	Rho-related GTP-binding protein RhoA-D-like.	0.904
ENSSGRP00000006713	LOC107591788	ENSSGRP00000006713	ENSSGRP00000060217	Rho-associated protein kinase 2-like.	Rho-related GTP-binding protein RhoA-B.	0.934
ENSSGRP00000006713	LOC107595767	ENSSGRP00000006713	ENSSGRP00000081376	Rho-associated protein kinase 2-like.	Rho guanine nucleotide exchange factor 1-like isoform X1.	0.431
ENSSGRP00000006713	LOC107600769	ENSSGRP00000006713	ENSSGRP00000080969	Rho-associated protein kinase 2-like.	Rho guanine nucleotide exchange factor 12-like isoform X1.	0.431
ENSSGRP00000006713	LOC107600972	ENSSGRP00000006713	ENSSGRP00000039225	Rho-associated protein kinase 2-like.	Rho-related GTP-binding protein RhoE-like.	0.643