(91 nodes) ECM-receptor interaction, and Type I hemidesmosome assembly network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107593980	Tetraspanin-11-like. (260 aa)
	ENSSGRP00000000721	annotation not available (126 aa)
	LOC107592710	Vascular cell adhesion protein 1-like. (833 aa)
	ENSSGRP00000005029	Collagen alpha-1(I) chain-like. (1188 aa)
	LOC107580050	Integrin beta-1-B-like. (428 aa)
	ENSSGRP00000005966	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2. (665 aa)
	ENSSGRP00000007361	Tenascin-like isoform X1. (447 aa)
	ENSSGRP00000007795	Integrin beta-3-like. (117 aa)
	ENSSGRP00000010712	Collagen alpha-4(IV) chain-like. (1464 aa)
	itgb3	Integrin beta 3. (806 aa)
	LOC107552753	Chondroadherin-like. (365 aa)
	tnr	Tenascin-R isoform X1. (1364 aa)
	LOC107601390	Integrin alpha-4-like isoform X1. (1016 aa)
	thbs1	Thrombospondin 1. (1174 aa)
	ENSSGRP00000014440	Thrombospondin 2/3/4/5. (986 aa)
	LOC107560736	Tetraspanin-11-like. (254 aa)
	ENSSGRP00000015858	Integrin alpha-2-like. (574 aa)
	ENSSGRP00000017783	Focal adhesion kinase 1-like isoform X1. (1020 aa)
	ENSSGRP00000018705	Collagen alpha-1(II) chain-like. (1280 aa)
	ENSSGRP00000019531	annotation not available (587 aa)
	ENSSGRP00000022404	Thrombospondin 2/3/4/5. (199 aa)
	ITGA7	Integrin subunit alpha 7. (1046 aa)
	ENSSGRP00000025383	Fibronectin-like. (2463 aa)
	LOC107573726	Integrin alpha-9-like. (567 aa)
	ENSSGRP00000029598	Integrin, beta 1a. (794 aa)
	LOC107568499	Thrombospondin-1-like. (1213 aa)
	ENSSGRP00000033151	Integrin beta-8-like. (763 aa)
	LOC107566918	Integrin beta-1-like isoform X1. (798 aa)
	thbs4	Thrombospondin 2/3/4/5. (954 aa)
	ENSSGRP00000035470	Collagen alpha-1(II) chain isoform X1. (1212 aa)
	ENSSGRP00000035958	Integrin alpha-5-like. (75 aa)
	ENSSGRP00000036078	Thrombospondin 2/3/4/5. (1174 aa)
	ENSSGRP00000039366	Proto-oncogene tyrosine-protein kinase Src-like isoform X1. (505 aa)
	LOC107587566	Syndecan-4-like. (215 aa)
	LOC107599356	Thrombospondin-4-B-like. (950 aa)
	ENSSGRP00000041858	Integrin alpha-8-like. (1032 aa)
	ENSSGRP00000041897	Thrombospondin-4-B-like isoform X1. (948 aa)
	ENSSGRP00000042345	Integrin alpha-5-like. (1030 aa)
	ENSSGRP00000045405	Meiosis-specific, MEI4 homolog (S. cerevisiae). (370 aa)
	Itgav	Integrin alpha V. (925 aa)
	ENSSGRP00000048698	CD151 antigen-like. (178 aa)
	tnn	Tenascin-N isoform X1. (1020 aa)
	LOC107549089	Thrombospondin-1-like. (1210 aa)
	ENSSGRP00000054799	Integrin alpha-4-like. (1022 aa)
	ENSSGRP00000055606	Integrin alpha-11-like. (1173 aa)
	cd151	CD151 antigen isoform X1. (254 aa)
	ENSSGRP00000057351	Collagen alpha-1(I) chain-like. (1218 aa)
	ENSSGRP00000062140	Integrin, alpha 6b. (1019 aa)
	ENSSGRP00000062886	Vitronectin-like. (393 aa)
	ENSSGRP00000063088	LOW QUALITY PROTEIN: von Willebrand factor-like. (2661 aa)
	LOC107601250	Integrin alpha-3-like isoform X1. (1058 aa)
	ENSSGRP00000068027	Collagen alpha-6(VI) chain-like. (1714 aa)
	ENSSGRP00000068707	Integrin alpha-11-like. (1166 aa)
	itga3	Integrin alpha 3. (999 aa)
	Col1a2	Collagen alpha-2(I) chain. (1297 aa)
	LOC107588061	Vascular cell adhesion protein 1-like. (812 aa)
	Itga8	Integrin alpha 8. (1044 aa)
	LOC107548575	Vitronectin-like isoform X1. (512 aa)
	LOC107582760	Chondroadherin-like. (363 aa)
	LOC107557321	Integrin alpha-3-like. (914 aa)
	ENSSGRP00000085656	Platelet glycoprotein 4-like. (372 aa)
	Comp	Cartilage oligomeric matrix protein. (725 aa)
	ENSSGRP00000087283	Integrin beta-3-like. (91 aa)
	LOC107590984	Platelet glycoprotein 4-like. (469 aa)
	LOC107585629	Thrombospondin-4-B isoform X1. (950 aa)
	ENSSGRP00000092607	Collagen alpha-2(IV) chain-like. (1446 aa)
	ENSSGRP00000092617	Collagen alpha-1(IV) chain-like. (961 aa)
	LOC107556289	Fibronectin-like isoform X1. (2495 aa)
	ENSSGRP00000094028	Thrombospondin 2/3/4/5. (870 aa)
	ENSSGRP00000094448	Collagen alpha-1(IV) chain-like isoform X1. (1160 aa)
	LOC107563813	Integrin beta-1-A-like. (825 aa)
	ENSSGRP00000097848	Thrombospondin 2/3/4/5. (1111 aa)
	ENSSGRP00000098128	Muscle-specific beta 1 integrin binding protein 2. (201 aa)
	ENSSGRP00000098954	Collagen alpha-1(I) chain-like. (1199 aa)
	ENSSGRP00000099117	Thrombospondin-1-like. (1178 aa)
	ENSSGRP00000099127	Collagen alpha-1(I) chain-like isoform X1. (1359 aa)
	ITGA6	Integrin subunit alpha 6. (1081 aa)
	ENSSGRP00000101015	Fibronectin-like. (2387 aa)
	LOC107595421	Syndecan-4-like. (208 aa)
	LOC107564862	Integrin beta-6-like. (709 aa)
	ENSSGRP00000102365	Integrin beta-6-like. (416 aa)
	ENSSGRP00000103723	Dystonin-like. (6868 aa)
	ENSSGRP00000106099	Plectin-like. (4541 aa)
	ENSSGRP00000106373	Collagen alpha-2(I) chain-like. (1297 aa)
	itgb7	Integrin beta-7 isoform X1. (767 aa)
	ENSSGRP00000108497	Multiple EGF-like-domains 11. (1065 aa)
	ENSSGRP00000108829	Integrin, alpha 3a. (835 aa)
	ENSSGRP00000109402	Collagen alpha-5(IV) chain-like. (1680 aa)
	COL4A6	Collagen alpha-6(IV) chain-like isoform X1. (1583 aa)
	Col4a5	Collagen alpha-5(IV) chain isoform X1. (1389 aa)
	ENSSGRP00000110102	Collagen alpha-6(IV) chain-like isoform X1. (1549 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COL4A6	Col4a5	ENSSGRP00000109440	ENSSGRP00000110088	Collagen alpha-6(IV) chain-like isoform X1.	Collagen alpha-5(IV) chain isoform X1.	0.617
COL4A6	ENSSGRP00000007795	ENSSGRP00000109440	ENSSGRP00000007795	Collagen alpha-6(IV) chain-like isoform X1.	Integrin beta-3-like.	0.705
COL4A6	ENSSGRP00000015858	ENSSGRP00000109440	ENSSGRP00000015858	Collagen alpha-6(IV) chain-like isoform X1.	Integrin alpha-2-like.	0.700
COL4A6	ENSSGRP00000033151	ENSSGRP00000109440	ENSSGRP00000033151	Collagen alpha-6(IV) chain-like isoform X1.	Integrin beta-8-like.	0.682
COL4A6	ENSSGRP00000035958	ENSSGRP00000109440	ENSSGRP00000035958	Collagen alpha-6(IV) chain-like isoform X1.	Integrin alpha-5-like.	0.699
COL4A6	ENSSGRP00000041858	ENSSGRP00000109440	ENSSGRP00000041858	Collagen alpha-6(IV) chain-like isoform X1.	Integrin alpha-8-like.	0.699
COL4A6	ENSSGRP00000042345	ENSSGRP00000109440	ENSSGRP00000042345	Collagen alpha-6(IV) chain-like isoform X1.	Integrin alpha-5-like.	0.699
COL4A6	ENSSGRP00000054799	ENSSGRP00000109440	ENSSGRP00000054799	Collagen alpha-6(IV) chain-like isoform X1.	Integrin alpha-4-like.	0.696
COL4A6	ENSSGRP00000055606	ENSSGRP00000109440	ENSSGRP00000055606	Collagen alpha-6(IV) chain-like isoform X1.	Integrin alpha-11-like.	0.696
COL4A6	ENSSGRP00000068707	ENSSGRP00000109440	ENSSGRP00000068707	Collagen alpha-6(IV) chain-like isoform X1.	Integrin alpha-11-like.	0.696
COL4A6	ENSSGRP00000087283	ENSSGRP00000109440	ENSSGRP00000087283	Collagen alpha-6(IV) chain-like isoform X1.	Integrin beta-3-like.	0.705
COL4A6	ENSSGRP00000102365	ENSSGRP00000109440	ENSSGRP00000102365	Collagen alpha-6(IV) chain-like isoform X1.	Integrin beta-6-like.	0.682
COL4A6	ENSSGRP00000109402	ENSSGRP00000109440	ENSSGRP00000109402	Collagen alpha-6(IV) chain-like isoform X1.	Collagen alpha-5(IV) chain-like.	0.434
COL4A6	Itga8	ENSSGRP00000109440	ENSSGRP00000074087	Collagen alpha-6(IV) chain-like isoform X1.	Integrin alpha 8.	0.699
COL4A6	Itgav	ENSSGRP00000109440	ENSSGRP00000046449	Collagen alpha-6(IV) chain-like isoform X1.	Integrin alpha V.	0.699
COL4A6	LOC107557321	ENSSGRP00000109440	ENSSGRP00000083902	Collagen alpha-6(IV) chain-like isoform X1.	Integrin alpha-3-like.	0.710
COL4A6	LOC107563813	ENSSGRP00000109440	ENSSGRP00000096716	Collagen alpha-6(IV) chain-like isoform X1.	Integrin beta-1-A-like.	0.702
COL4A6	LOC107564862	ENSSGRP00000109440	ENSSGRP00000102256	Collagen alpha-6(IV) chain-like isoform X1.	Integrin beta-6-like.	0.702
COL4A6	LOC107566918	ENSSGRP00000109440	ENSSGRP00000033427	Collagen alpha-6(IV) chain-like isoform X1.	Integrin beta-1-like isoform X1.	0.702
COL4A6	LOC107573726	ENSSGRP00000109440	ENSSGRP00000026417	Collagen alpha-6(IV) chain-like isoform X1.	Integrin alpha-9-like.	0.696